Glyceryl Palmitoleate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Glyceryl Palmitoleate?

Glyceryl Palmitoleate is an ester formed by joining glycerin with palmitoleic acid, a monounsaturated fatty acid found in sources such as macadamia nut oil, sea buckthorn oil and animal fats. Chemically known as 9-hexadecenoic acid, 2,3-dihydroxypropyl ester, it looks and behaves like a lightweight oily liquid. The cosmetic world first took interest in the ingredient in the late twentieth century when formulators searched for plant-derived alternatives to heavier animal-based emulsifiers. Today most Glyceryl Palmitoleate used in beauty products is produced through a controlled reaction that bonds vegetable-derived glycerin with purified palmitoleic acid under heat and vacuum, then refines the mixture to remove any impurities. You will spot it most often in moisturizers, anti-aging creams, nutrient-rich masks, creamy cleansers, and soothing after-sun lotions where a smooth non-greasy feel is desired.

Glyceryl Palmitoleate’s Cosmetic Benefits/Uses

In topical formulas Glyceryl Palmitoleate serves one key purpose that delivers several practical perks for both the product and the skin.

  • Emulsifying: It helps oil and water stay blended so the cream or lotion remains stable from the first pump to the last swipe. A well-emulsified product feels silky, spreads evenly, resists separation in the jar, and improves the delivery of other active ingredients for more consistent results.

Who Can Use Glyceryl Palmitoleate

Glyceryl Palmitoleate is generally suitable for dry, normal and combination skin since its lightweight fatty nature adds softness without leaving a heavy residue. Sensitive skin usually tolerates it well because it lacks common irritants or acids that can sting, yet those with very oily or acne prone skin may prefer lighter alternatives as fatty esters can occasionally feel too rich and contribute to congestion when used in high amounts.

The ingredient itself can be vegan friendly given that manufacturers commonly derive both the glycerin and palmitoleic acid from plant oils. That said some suppliers still source the fatty component from animal fats, so strict vegans and vegetarians should look for products that clearly state plant sourced or certified vegan on the label.

Current safety data show no known issues for pregnant or breastfeeding women when Glyceryl Palmitoleate is applied to the skin in standard cosmetic concentrations. This is not medical advice so anyone who is expecting or nursing should ask a healthcare professional before adding new products to their routine just to be safe.

The ester is not considered photosensitizing and will not make the skin more prone to sunburn. It also plays nicely with most other commonly used skincare ingredients and does not interfere with makeup or sunscreen wear.

Potential Side Effects/Adverse Reactions

Responses to topical Glyceryl Palmitoleate differ from person to person. The points below outline potential side effects but they are uncommon when the ingredient is properly formulated and used at typical cosmetic levels.

  • Mild irritation or redness
  • Allergic contact dermatitis in individuals sensitive to fatty esters or trace impurities
  • Acne flare ups in very oily or blemish prone skin when used in rich leave on formulas

If any of these reactions occur discontinue use and consult a qualified healthcare professional for guidance.

Comedogenic Rating

Rating: 2/5. Glyceryl Palmitoleate is a lightweight fatty ester, so it is less likely to clog pores than heavier waxes or butters, yet its oily nature can still linger on the skin. Most users will not notice breakouts at the low levels used in creams and lotions, but people who are highly prone to congestion could experience small bumps if the overall formula is already rich. In short, it is generally fine for mild to moderately acne prone skin but may not be ideal for very blemish prone complexions when included in high-oil products. The rating may vary slightly depending on what other ingredients share the same formula, since thicker occlusives can raise the overall pore-clogging potential.

Summary

Glyceryl Palmitoleate acts mainly as an emulsifier, letting oil and water blend into a smooth stable mixture while also lending a soft cushioned feel to the finished product. By pairing glycerin with palmitoleic acid, it anchors watery and oily phases together so creams stay homogenous and spread evenly on the skin.

The ingredient is moderately popular, showing up more often in natural or plant focused lines than in mass market formulas that tend to favor classic glyceryl stearate or PEG based emulsifiers. Its appeal lies in the light silky touch that avoids the waxy drag of heavier options.

Safety reviews find it non irritating for most skin types with a low risk of sensitization or toxicity when applied at cosmetic levels. As with any new skincare ingredient, it is smart to do a small patch test before full use to confirm personal compatibility.

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