Glyceryl Pentadecanoate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Glyceryl Pentadecanoate?

Glyceryl Pentadecanoate is the monoester formed when glycerin, a well known skin friendly humectant, reacts with pentadecanoic acid, a 15-carbon saturated fatty acid sometimes found in dairy fat and certain plant oils. This pairing yields a waxy, skin compatible ingredient that carries traits of both its parents: the slip and moisturising feel of glycerin based esters plus the mild surface activity of medium-chain fatty acids.

The ingredient appeared in cosmetic labs in the late twentieth century when formulators began searching for gentle alternatives to traditional detergents. Glyceryl esters offered a way to cleanse and stabilise products without the tight, dry after-feel linked to stronger surfactants, so Glyceryl Pentadecanoate quickly joined the roster of multifunctional helpers used in skincare.

Commercial production relies on an esterification process. Vegetable or dairy sourced pentadecanoic acid is heated with plant derived glycerin in the presence of a food grade catalyst. Once the reaction reaches completion the mixture is purified, yielding a nearly odourless off-white solid that melts easily into cosmetic bases.

You will spot Glyceryl Pentadecanoate in facial cleansers, creams, body lotions, masks, sunscreens, lightweight serums and even some hair conditioners. Its ability to both lift away grime and hold oil and water phases together makes it valuable across rinse-off and leave-on products.

Glyceryl Pentadecanoate’s Cosmetic Benefits/Uses

In formulas this ingredient shines because it can play more than one role

  • Cleansing: Its fatty acid backbone allows it to attach to oils and impurities while the glycerin portion keeps it mild and moisturising. This combination helps dissolve makeup and excess sebum without stripping the skin’s natural barrier
  • Emulsifying: Acting as a bridge between oil and water, it stabilises creams and lotions so they stay smooth and uniform over time. A stable emulsion spreads better, feels lighter and delivers actives more evenly

Who Can Use Glyceryl Pentadecanoate

Glyceryl Pentadecanoate is generally considered friendly for most skin types including dry, normal, combination and sensitive skin, thanks to its mild cleansing action and low likelihood of disrupting the moisture barrier. Very oily or acne prone users may want lighter textures since fatty esters can occasionally feel rich on skin already producing excess sebum.

The ingredient itself can be suitable for vegans and vegetarians if both the glycerin and pentadecanoic acid are sourced from plants. Some manufacturers still use dairy derived pentadecanoic acid, so anyone avoiding animal by-products should verify the supply chain or look for a vegan label.

Current safety data shows no known issues for pregnant or breastfeeding women when the ingredient is used in normal cosmetic concentrations. This is not medical advice and anyone who is expecting or nursing should discuss new skincare products with their healthcare provider to be on the safe side.

Glyceryl Pentadecanoate is not known to cause photosensitivity and does not increase the skin’s vulnerability to the sun. Standard daily sunscreen habits are still recommended for overall skin health.

Potential Side Effects/Adverse Reactions

Side effects from topical Glyceryl Pentadecanoate can vary from person to person. The points below list potential reactions yet most users will not experience them when the ingredient is formulated correctly.

  • Mild redness or irritation
  • Allergic contact dermatitis in individuals sensitive to fatty esters
  • Temporary eye stinging if the product accidentally gets into the eyes
  • Clogged pores or breakouts in very acne prone skin when used in heavy, occlusive formulas

If you notice any discomfort, stop using the product and consult a healthcare professional for guidance.

Comedogenic Rating

Rating: 2 out of 5

Glyceryl Pentadecanoate sits on the lower side of the scale because its glycerin segment keeps it lightweight while the 15-carbon fatty acid tail can still linger on skin and mix with sebum. In most balanced formulations it rinses or absorbs without blocking pores, yet thicker occlusive products containing high levels of this ester may feel heavy on skin that already overproduces oil.

Acne-prone users can generally tolerate the ingredient in well-formulated, lighter products but should steer clear of dense balms or rich creams where the concentration is higher.

Comedogenicity also depends on the full formula. When paired with fast-absorbing oils or used at low percentages the clogging risk drops even further.

Summary

Glyceryl Pentadecanoate acts as a mild cleanser and reliable emulsifier. The glycerin part draws water and cushions the skin while the pentadecanoic acid segment grabs onto oils, letting the molecule lift away grime and hold oil and water together in smooth, stable blends.

It is not as famous as flashier actives like hyaluronic acid or niacinamide but formulators appreciate its multitasking nature so you will quietly find it in a variety of cleansers, lotions and sunscreens.

Current research and decades of use show it is generally safe for most people with only a small chance of irritation or pore blockage. As with any new cosmetic, perform a simple patch test when trying a product that contains Glyceryl Pentadecanoate to make sure your skin agrees with it.

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