Glycyrrhiza Uralensis Callus Extract: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Glycyrrhiza Uralensis Callus Extract?

Glycyrrhiza Uralensis Callus Extract comes from the licorice plant that grows across parts of Asia. Instead of harvesting the full grown root, scientists take a tiny piece of plant tissue and place it in a sterile nutrient solution. The tissue multiplies into a soft mass called a callus, which is then filtered and processed into an extract rich in the plant’s natural compounds. These compounds often include flavonoids and saponins known for calming and antioxidant properties.

Licorice root has been part of traditional beauty rituals for centuries, prized for its ability to soothe the skin and brighten tone. Callus culture technology is a modern spin on that history. By growing the tissue in a lab, manufacturers avoid soil contaminants, control potency and use far less farmland. The result is a consistent, eco-friendly ingredient that slots easily into water based cosmetic formulas.

You will most often find Glycyrrhiza Uralensis Callus Extract in lightweight serums, brightening essences, sheet masks, daily moisturizers, anti-aging creams and after-sun products where gentle soothing and conditioning are needed.

Glycyrrhiza Uralensis Callus Extract’s Cosmetic Benefits/Uses

This extract is mainly valued for one clear job in skin care formulations.

  • Skin conditioning: It helps keep skin soft, supple and balanced. The natural antioxidants support the skin’s barrier, the soothing agents can calm visible redness and the lightweight texture adds a touch of hydration without heaviness, making it suitable for both oil based and water based products.

Who Can Use Glycyrrhiza Uralensis Callus Extract

Thanks to its gentle nature and lightweight feel, Glycyrrhiza Uralensis Callus Extract suits almost every skin type including dry, normal, combination, oily and sensitive skin. Those prone to redness or irritation may find its calming properties particularly welcoming. The only group that might need to proceed with extra caution is anyone with a known allergy to licorice or other Fabaceae family plants as cross reactions, though uncommon, can happen.

The extract is plant based and produced in controlled lab conditions with no animal derived materials, so it is typically considered vegan and vegetarian friendly.

No studies flag this ingredient as a risk during pregnancy or breastfeeding when used topically in cosmetic amounts. Still, this is not medical advice and anyone who is pregnant or nursing should ask a qualified healthcare professional before adding new products to their routine.

Licorice derived ingredients are not known to cause photosensitivity. Standard daytime sun protection habits are still recommended but no special UV precautions are needed solely because of this extract.

Potential Side Effects/Adverse Reactions

Responses to Glycyrrhiza Uralensis Callus Extract differ from one person to another. The points below list potential side effects yet most users should not expect to encounter them when the ingredient is formulated and used as intended.

  • Mild redness or stinging in highly reactive skin, typically short lived
  • Allergic contact dermatitis in individuals sensitive to licorice or related plants
  • Unwanted lightening of dark spots if used alongside multiple brightening actives, though this is rare

If any discomfort, persistent redness or rash appears stop using the product and seek advice from a healthcare professional.

Comedogenic Rating

Rating: 0–1. Glycyrrhiza Uralensis Callus Extract is water based and contains virtually no oily or waxy fractions that would clog pores. Its primary constituents are soothing flavonoids and antioxidant molecules that sit lightly on the skin, so it earns a low score on the comedogenic scale. This makes the extract well suited to acne-prone or breakout-prone skin. As with any ingredient, overall pore-clogging risk depends on the entire product formula and how it is layered with other products.

Summary

Glycyrrhiza Uralensis Callus Extract conditions skin by supplying calming flavonoids, gentle antioxidants and a whisper of hydration that helps keep the barrier comfortable and balanced. It has become a quiet favorite in modern formulations that aim for clean, eco-minded sourcing though it is still less famous than powerhouse actives like niacinamide or vitamin C. Most safety reviews rate it as low risk for irritation or sensitization when used in normal cosmetic concentrations. That said, everyone’s skin is unique so it is smart to patch test any new product containing this licorice-derived extract before full-face use.

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