Hexoxyethyl Diethylammonium Phosphate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Hexoxyethyl Diethylammonium Phosphate?

Hexoxyethyl Diethylammonium Phosphate is a specialized blend made from hexyloxyethanol, diethylamine and phosphoric acid. When these three parts react they form a phosphate ester that acts as a shield against metal damage. It first drew attention in industrial coatings where keeping metal tools free from rust is critical. Cosmetic chemists later noticed that the same protective skill could help formulas stay stable when stored in metal tanks or delivered through metal pumps.

The ingredient is produced by carefully mixing hexyloxyethanol with phosphoric acid to create a partial ester, then neutralizing the mix with diethylamine. The result is a clear liquid that dissolves well in water and many solvents, making it easy to add during the cooling stage of a batch.

Today you are most likely to spot Hexoxyethyl Diethylammonium Phosphate in water based sprays, serums, toners and sheet mask essences that sit in aluminum or tinplate packaging. It also shows up in refill pouches and bulk salon products that spend months inside stainless steel drums before being poured into retail bottles.

Hexoxyethyl Diethylammonium Phosphate’s Cosmetic Benefits/Uses

In everyday beauty items this ingredient serves one clear purpose: it works as an anticorrosive agent. By forming a microscopic barrier between the formula and any metal surface it helps stop rust particles from leaching into the product. This keeps the color and scent true, prevents gritty specks from forming and extends shelf life so the user enjoys the product exactly as intended until the last drop.

Who Can Use Hexoxyethyl Diethylammonium Phosphate

Because it sits in the formula to protect against metal corrosion instead of acting directly on the skin, this ingredient is considered neutral for all skin types including dry, oily, combination and sensitive. It is water soluble, used at very low levels and does not leave a film so even acne prone or reactive complexions usually tolerate it well.

Hexoxyethyl Diethylammonium Phosphate is synthetically produced without any animal derived raw materials which makes it suitable for both vegetarians and vegans.

Current safety data shows no reproductive or developmental hazards so products containing it are generally viewed as compatible with use during pregnancy or while breastfeeding. That said this is not medical advice and anyone who is pregnant or nursing should show the full ingredient list of any product to a qualified health professional before using it.

The molecule does not absorb UV light or make skin more sensitive to sunlight so it is not considered photosensitising.

Potential Side Effects/Adverse Reactions

Reactions to topical Hexoxyethyl Diethylammonium Phosphate vary from person to person. The points below describe potential side effects that may occur in rare cases. Assuming the ingredient is used at appropriate levels most users will not experience these problems.

  • Mild skin irritation – a temporary feeling of warmth stinging or itchiness that subsides after rinsing
  • Contact dermatitis – small red bumps or patches in people with a known sensitivity to phosphate esters or amine salts
  • Eye irritation – watering or mild burning if the product accidentally gets into the eyes
  • Allergic reaction – very rare swelling or hives in individuals already allergic to related compounds

If any of these issues arise discontinue use and seek medical advice if symptoms persist or worsen.

Comedogenic Rating

Rating: 0 / 5

Hexoxyethyl Diethylammonium Phosphate sits dissolved in the water phase and is present at very low concentrations, so it does not leave oily residues that could block pores. It has no fatty chains known to clog follicles and it quickly rinses away with normal cleansing, which is why it earns a solid zero on the comedogenic scale.

That means the ingredient is generally considered safe for people who are prone to acne or frequent breakouts.

Because it is used mainly to protect the formula rather than interact with skin, its presence does not alter sebum production or skin texture, two factors often linked to clogged pores.

Summary

Hexoxyethyl Diethylammonium Phosphate is a behind-the-scenes helper that guards water based cosmetics from metal-induced discoloration, off odors and shortened shelf life. It does this by forming a thin ionic layer that blocks contact between the formula and any metal surface it touches, stopping rust before it can start.

The ingredient is far from a household name and you will mostly see it in niche or professional products that rely on metal packaging, so its overall popularity is modest compared with headline act ingredients like hyaluronic acid or niacinamide.

Current data shows it to be low risk for irritation, noncomedogenic and vegan friendly, making it a safe bet for most users. Still, everyone’s skin is unique so it is wise to patch test any new product that lists Hexoxyethyl Diethylammonium Phosphate, just to be sure it agrees with you.

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