Hexyldecyl Myristoyl Methylaminopropionate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Hexyldecyl Myristoyl Methylaminopropionate?

Hexyldecyl Myristoyl Methylaminopropionate is a lab crafted ester made by joining a fatty alcohol (hexyldecanol) with myristic acid and a small amino acid-like linker. The result is a silky, oil-like liquid that spreads easily on skin without feeling greasy. It was first explored in the late 1990s when formulators searched for plant-friendly substitutes to mineral oil and silicones. By tweaking the ratio of fatty chains, chemists discovered this molecule delivered cushiony slip and a soft finish that consumers liked in premium skin care.

Production starts with renewable coconut or palm-derived fatty acids. These are reacted with hexyldecanol under controlled heat, then combined with methylaminopropionic acid and finally neutralized to reach a skin-friendly pH. The finished ingredient is clear to pale yellow and virtually odorless, making it easy to add to a wide range of personal care items.

You will most often spot Hexyldecyl Myristoyl Methylaminopropionate in moisturizers, hydrating masks, creamy cleansers, soothing after-sun lotions, nourishing eye creams and high-end anti-aging serums where a light, comforting skin feel is desired.

Hexyldecyl Myristoyl Methylaminopropionate’s Cosmetic Benefits/Uses

This multitasking ester improves both the feel and performance of topical products.

  • Skin conditioning – coats the surface in a thin protective layer that traps moisture, leaving skin softer and smoother
  • Emollient – fills in microscopic gaps between skin cells so formulas glide on effortlessly and dry patches feel less rough

Who Can Use Hexyldecyl Myristoyl Methylaminopropionate

This ingredient is generally well tolerated by all skin types including dry, normal, combination and oily because it provides lightweight moisture without a heavy or occlusive feel. Sensitive skin usually handles it well too thanks to its low odor and minimal irritant potential, though individuals with very reactive skin should still check the full product formula for other trigger ingredients.

Vegetarians and vegans can use products containing Hexyldecyl Myristoyl Methylaminopropionate because it is synthesized from plant sourced fatty acids like coconut or sustainable palm and contains no animal derived components.

Current safety data show no specific risks for women who are pregnant or breastfeeding when this ester is applied topically in normal cosmetic concentrations. That said this information is not medical advice and anyone who is expecting or nursing should review any skincare routine with a qualified healthcare professional.

The molecule is not known to cause photosensitivity, so it does not make skin more prone to sunburn. As always daily sunscreen is still recommended for overall skin health.

Potential Side Effects/Adverse Reactions

Reactions to topical Hexyldecyl Myristoyl Methylaminopropionate vary from person to person. The following list covers potential effects that could occur but they are uncommon when the ingredient is used correctly in a well formulated product.

  • Mild irritation a small number of users may notice transient redness or warmth especially if their skin barrier is already compromised
  • Contact dermatitis very rarely an allergic response can develop which may present as itching flaking or swelling
  • Eye stinging if the product accidentally gets into the eyes temporary discomfort or watering can occur
  • Acne flare although the ester is lightweight some people who are extremely acne prone may see clogged pores if they layer multiple heavy products

If any of these issues arise discontinue use and seek guidance from a healthcare professional if symptoms persist or worsen.

Comedogenic Rating

Rating: 1/5

Hexyldecyl Myristoyl Methylaminopropionate earns a low score of 1 because its branched structure and ester linkage keep it lightweight and help it spread thinly without forming a heavy film that can block pores. Studies on similar fatty esters show minimal pore clogging at typical use levels and consumer feedback rarely links this molecule to persistent breakouts.

Suitable for acne-prone skin, although exceptionally reactive or highly oily users might still prefer very low-oil formulas.

Because it softens skin and improves slip, it often replaces heavier plant oils in modern moisturizers which can further reduce clogging risk.

Summary

Hexyldecyl Myristoyl Methylaminopropionate is a plant-derived ester that conditions skin and acts as a feather-light emollient. It smooths rough areas by filling tiny gaps between cells and leaves a breathable protective layer that slows moisture loss.

While not as famous as squalane or jojoba oil, formulators value it for the silky afterfeel it brings to premium creams, masks and cleansers. Its moderate cost and easy compatibility with other ingredients mean its presence is quietly growing in new launches.

Current safety data show very low irritation or allergen potential. Still, skin is individual so it is smart to patch test any new product containing this ester before full-face use.

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