Human Placental Lipids: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Human Placental Lipids?

Human Placental Lipids are fats taken from healthy placentas that are collected after childbirth. Once the placentas are tested and cleared, lipid specialists separate the fat fraction using gentle solvents and low heat. The result is a blend rich in phospholipids, cholesterol and essential fatty acids, all of which are naturally present in our own skin and hair.

Interest in placental extracts started in the middle of the twentieth century when beauty brands looked for biologically active materials that could give skin a youthful look. Over time companies refined the process, keeping only the lipid portion to reduce the risk of irritation and to focus on the ingredients that support the skin barrier and hair cuticle.

Today the ingredient shows up in leave-on and rinse-off hair conditioners, restorative scalp treatments, anti aging face creams, nutrient-dense masks and rich night moisturizers. Manufacturers value its compatibility with human tissue and its ability to blend easily into oils, butters and emulsions.

Human Placental Lipids’s Cosmetic Benefits/Uses

In formulas Human Placental Lipids offer two key benefits

  • Hair Conditioning: The lipids coat the hair shaft helping to smooth rough cuticles, add softness and reduce static. This can make hair feel silkier and look shinier while improving combability.
  • Skin Conditioning: Because their fatty acid profile is similar to that of skin sebum, these lipids reinforce the skin barrier, curb moisture loss and leave the surface feeling supple. They can also give creams a richer feel without making them greasy.

Who Can Use Human Placental Lipids

Because the lipid profile mirrors that of natural sebum most skin types, including dry, normal and mature skin, tend to tolerate Human Placental Lipids well. Very oily or acne-prone complexions might find rich lipid formulas too occlusive, so lightweight products or lower concentrations are advised for those users.

The ingredient comes from human afterbirth which means it is not suitable for vegans or vegetarians who avoid animal-derived materials.

No specific data show harm to women who are pregnant or breastfeeding when the ingredient is applied to intact skin, yet research is limited. This is not medical advice and anyone who is pregnant or nursing should run products containing Human Placental Lipids past a qualified doctor just to be safe.

The ingredient does not increase photosensitivity so it can be used day or night without added sun sensitivity concerns.

Potential Side Effects/Adverse Reactions

Side effects and reactions can vary from person to person. The points below describe potential issues that are unlikely for the average user when the ingredient is formulated and used correctly.

  • Contact irritation – mild redness, itching or stinging in individuals sensitive to biological extracts
  • Allergic reaction – very rare immune response leading to swelling, rash or hives
  • Breakouts or pore congestion – possible in those who are highly acne-prone when using rich leave-on products
  • Ethical or emotional discomfort – some users may feel uneasy about the human origin and choose to avoid it

If any negative effect occurs stop using the product and consult a healthcare professional or dermatologist.

Comedogenic Rating

Rating: 2 out of 5

Human Placental Lipids are rich in cholesterol and essential fatty acids that integrate well with skin sebum, yet they are not as heavy or waxy as ingredients like cocoa butter or coconut oil. This places them in the low to moderate clogging range. Most users should not see an uptick in blackheads or whiteheads, but highly acne-prone individuals may notice congestion if the formula is very rich or layered under occlusive products. Overall the ingredient is generally acceptable for breakout-prone skin if used in lightweight or rinse-off formats.

Comedogenicity can vary depending on the finished formula. When combined with non-pore-clogging oils or used in small amounts the risk of breakouts drops further.

Summary

Human Placental Lipids condition hair by forming a smoothing film over the cuticle that boosts shine and reduces static. On skin they reinforce the natural lipid barrier, slow moisture loss and leave a supple afterfeel. These effects come from their blend of phospholipids, cholesterol and fatty acids which mimic the skin’s own protective oils.

The ingredient enjoys a niche but steady presence in premium hair masks, scalp serums and anti aging creams. Its effectiveness is appreciated by formulators, yet sourcing limitations and ethical concerns keep it from mass popularity.

When sourced from screened afterbirth and properly purified the safety record is good with irritation or allergy being rare. As with any new cosmetic ingredient, do a small patch test before regular use to make sure your skin or scalp agrees with it.

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