Hydrogenated Lysophosphatidylcholine: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Hydrogenated Lysophosphatidylcholine?

Hydrogenated Lysophosphatidylcholine is a modified phospholipid created by adding hydrogen to lysophosphatidylcholine, a naturally occurring component of cell membranes. Manufacturers usually start with plant-derived lecithin from soybeans or sunflower seeds, although egg yolk can be a source as well. The lecithin is first refined to isolate lysophosphatidylcholine, then exposed to hydrogen gas in the presence of a catalyst. This hydrogenation step saturates the fatty acid portion, making the molecule more stable against oxidation and heat.

Cosmetic chemists first explored phospholipids in the 1970s for their affinity with skin lipids. Over time they learned that hydrogenating the molecule extends shelf life and widens the range of formulas it can tolerate. Today you will spot Hydrogenated Lysophosphatidylcholine in facial cleansers, micellar waters, makeup removers, lightweight lotions, nourishing creams, sheet masks, anti-aging serums and after-sun treatments.

Hydrogenated Lysophosphatidylcholine’s Cosmetic Benefits/Uses

Below are the main reasons formulators turn to this multitasking ingredient

  • Cleansing – Its amphiphilic structure attracts both water and oil, helping lift away dirt, sunscreen and makeup without leaving a heavy residue
  • Skin conditioning – Because it resembles the skin’s own lipids it can support the moisture barrier, leaving skin feeling soft and comfortable
  • Emulsifying – It helps water and oil mix smoothly, creating stable creams and lotions with an elegant, non-greasy feel

Who Can Use Hydrogenated Lysophosphatidylcholine

This ingredient is generally well tolerated by most skin types. Dry and sensitive skin often benefit from its barrier supporting qualities while normal and combination skin appreciate its light feel. Oily or acne prone skin can usually use it without problems since it does not add heavy grease, though those extremely prone to breakouts may still prefer patch testing first.

Hydrogenated Lysophosphatidylcholine can be derived from soybeans, sunflower seeds or egg yolk. If the product is certified vegan or specifies plant based sourcing it is suitable for vegans and vegetarians. When the label is unclear people following plant only lifestyles should contact the manufacturer for confirmation.

No data links this ingredient to problems during pregnancy or breastfeeding when used topically. Still this is not medical advice and anyone who is pregnant or nursing should have a doctor review their entire skincare routine to be safe.

It does not increase photosensitivity so you do not have to worry about heightened sun reaction solely from this ingredient. Those with a known soy or egg allergy should check source information since trace proteins could remain and trigger a response.

Potential Side Effects/Adverse Reactions

Reactions to topical Hydrogenated Lysophosphatidylcholine differ from person to person. The points below outline potential issues. These events are uncommon when the ingredient is formulated and used correctly.

  • Mild redness or stinging on very sensitive or broken skin
  • Allergic contact dermatitis in individuals sensitive to soy or egg derived materials
  • Rare clogged pores in users highly prone to comedones
  • Eye irritation if the product accidentally gets into the eyes

If you notice any of the above discontinue use and seek advice from a healthcare professional.

Comedogenic Rating

Rating: 1 out of 5. Hydrogenated Lysophosphatidylcholine is a lightweight phospholipid that integrates easily with skin lipids without forming an occlusive, greasy film. Its molecular structure is similar to natural skin components, so it tends to sit on the surface and rinse away rather than clog pores. Most published ingredient lists show it used at low concentrations, which further limits the chance of buildup. This makes it suitable for people who are prone to acne or frequent breakouts. If a formula also contains heavy oils or waxes those other ingredients will have more influence on pore clogging than this phospholipid.

Summary

Hydrogenated Lysophosphatidylcholine acts as a gentle cleanser, skin conditioner and emulsifier. Its amphiphilic head attracts water while its saturated tail grabs oils, lifting grime and makeup when rinsed. Because the molecule resembles the lipids in our own skin it can slip into the outer layer and help reinforce the moisture barrier, leaving skin soft. In emulsions it positions itself at the water-oil border and holds formulas stable so lotions feel light rather than greasy.

The ingredient sits in the middle ground of popularity. It appears consistently in micellar waters and upgraded cleansers, yet it is not as common as mainstream surfactants like coco-glucoside so you may need to read labels to spot it.

Current research and decades of cosmetic use show a low risk of irritation or sensitization for most people. Still every skin is unique so it is smart to perform a simple patch test when you try a new product that contains Hydrogenated Lysophosphatidylcholine.

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