Hydrolyzed Beta-Glucan: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Hydrolyzed Beta-Glucan?

Hydrolyzed beta-glucan is a broken-down form of beta-glucan, a natural sugar found in the cell walls of oats, barley, mushrooms and some yeasts. Through hydrolysis the long beta-glucan chains are cut into shorter pieces that dissolve more easily in water and can be taken up by the skin. This smaller size helps the ingredient slip into the outer layers of skin where it can get to work.

Beta-glucan first gained attention in the 1960s for its soothing effect on irritated skin. Early cosmetic chemists used whole beta-glucan but soon noticed it was too large to work well on the surface. By the 1990s manufacturers began hydrolyzing beta-glucan with gentle acids or enzymes, creating the form most common in skincare today.

To make it, the raw beta-glucan is soaked in water, treated with a food-grade acid or an enzyme, then neutralized and filtered. The result is a clear liquid or light powder that blends smoothly into creams, gels and serums.

You will spot hydrolyzed beta-glucan in moisturizers, anti-aging serums, sheet masks, after-sun gels and soothing treatments aimed at reducing redness or tightness.

Hydrolyzed Beta-Glucan’s Cosmetic Benefits/Uses

In formulas, hydrolyzed beta-glucan serves one main role that delivers several visible perks for skin.

Skin conditioning: It forms a light film that pulls water to the surface and holds it there, helping skin feel smoother and look plumper. Regular use can soften rough patches, ease the appearance of fine lines and support a calm balanced complexion.

Who Can Use Hydrolyzed Beta-Glucan

This moisturising sugar fragment is gentle enough for every skin type including sensitive, dry, oily and combination skin. Because it is water soluble and non occlusive it rarely triggers breakouts or excess oil, making it a friendly option for acne-prone complexions as well. No specific skin type is known to be incompatible with hydrolyzed beta-glucan.

Most commercial sources come from plants or fermentation so the ingredient is typically free of animal derivatives, which makes it suitable for vegans and vegetarians. Anyone following a cruelty-free lifestyle should still check the overall product for animal testing policies.

The molecule has no known hormone-like activity so it is generally viewed as safe during pregnancy and breastfeeding. This is not medical advice and pregnant or nursing women should show any skincare product they plan to use to a doctor to be on the safe side.

Hydrolyzed beta-glucan does not increase photosensitivity. Normal daytime sun protection habits are still recommended when using any skincare routine.

Potential Side Effects/Adverse Reactions

Responses to topical hydrolyzed beta-glucan can vary between individuals. The effects listed below are potential issues that may occur in rare cases. When the ingredient is formulated properly most people will not experience negative reactions.

  • Redness or itching due to individual sensitivity
  • Mild stinging on compromised or freshly exfoliated skin
  • Allergic contact dermatitis in those with a specific beta-glucan allergy
  • Breakout or congestion if combined with highly occlusive bases
  • Irritation linked to other ingredients in the final product such as fragrances or preservatives

If any of these reactions occur stop using the product and seek guidance from a healthcare professional.

Comedogenic Rating

Rating: 0/5 – Hydrolyzed beta-glucan is a water-soluble sugar fragment that does not leave an oily or occlusive film likely to block pores. Because it sits lightly on the surface and rinses away easily, it carries virtually no risk of trapping sebum or dead cells that can spark breakouts. This makes it a safe pick for acne-prone or congestion-prone skin. Unless the finished formula contains other pore-clogging ingredients, hydrolyzed beta-glucan itself will not trigger comedones.

One extra note: some products pair it with heavy plant oils or butters for added richness. If you are sensitive to those richer bases check the full ingredient list to be sure the overall product still fits your needs.

Summary

Hydrolyzed beta-glucan is mainly a skin-conditioning agent that boosts hydration by attracting water and forming a light protective veil. Its smaller, hydrolyzed size lets it sink into the upper skin layers where it plumps, softens and helps calm visible redness.

The ingredient sits in the happy middle of popularity: not as famous as hyaluronic acid yet common enough to show up in moisturizers, soothing serums and sheet masks from both boutique and drugstore brands. Formulators like it because it plays well with most actives and thickeners and offers a clean label appeal.

Overall safety is high. It is non-comedogenic, non-photo-sensitizing and suitable for nearly all skin types including sensitive, acne-prone and pregnant users. As with any new skincare product do a quick patch test to rule out personal sensitivities before applying it to a larger area.

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