Hydrolyzed Horse Placenta Extract: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Hydrolyzed Horse Placenta Extract?

Hydrolyzed Horse Placenta Extract is a cosmetic ingredient obtained from the placenta of horses. The raw placental tissue is rich in proteins, amino acids, peptides, vitamins and minerals that support skin vitality. To turn this raw material into a skin-friendly ingredient the placenta is first cleaned and sterilized, then broken down through acid, enzymatic or other hydrolysis methods. This controlled breakdown reduces the size of the proteins so they can disperse easily in cosmetic formulas and absorb more readily into the skin.

The use of animal placenta in beauty has roots in traditional wellness practices, particularly in parts of Asia where placental treatments were prized for restoring a youthful look. Modern cosmetic science picked up on these traditions in the late 20th century, refining the extraction and hydrolysis steps to meet safety standards and create a stable ingredient suitable for mass-market products.

You’ll most often find Hydrolyzed Horse Placenta Extract in anti-aging creams, serums, sheet masks, high-performance moisturizers and post-treatment soothing products. Its small peptide content allows it to blend well with water-based or light emulsion formulas, making it popular in both luxury and clinical skin care lines.

Hydrolyzed Horse Placenta Extract’s Cosmetic Benefits/Uses

This ingredient is valued for one primary function within cosmetic formulas.

Skin protecting: The mix of peptides and amino acids forms a light conditioning layer on the skin surface that helps guard against environmental stressors and moisture loss. By supporting the skin’s natural barrier it can leave the complexion feeling softer, more resilient and better able to retain hydration, which in turn promotes a smoother more radiant appearance.

Who Can Use Hydrolyzed Horse Placenta Extract

Most skin types, including normal, dry and mature skin, generally tolerate Hydrolyzed Horse Placenta Extract well thanks to its mild barrier-supporting nature. Oily or acne-prone skin can also use it, though very sensitive or reactive complexions might prefer to proceed with caution since any biologically active protein mix has a small chance of triggering irritation.

The ingredient is animal-derived, so it is not suitable for vegans or strict vegetarians. Those who avoid animal by-products for ethical or religious reasons will want to skip formulas containing it.

No specific data suggests that topical use poses a risk to pregnant or breastfeeding women, but because the source is animal tissue and each pregnancy is unique it is best to consult a healthcare provider before adding products with this extract.

Hydrolyzed Horse Placenta Extract does not increase photosensitivity, so there is no additional sun-related caution beyond normal daily sunscreen use.

Potential Side Effects/Adverse Reactions

Individual responses to Hydrolyzed Horse Placenta Extract vary. The points below outline possible side effects, though most users will not encounter them when the ingredient is properly formulated.

  • Skin irritation – redness, stinging or burning can occur in very sensitive individuals
  • Allergic reaction – itching, swelling or rash due to immune sensitivity to animal proteins
  • Contact dermatitis – prolonged inflammation if the skin barrier is already compromised
  • Follicular congestion – rare instances of clogged pores in those highly prone to comedones

If any discomfort or visible reaction develops discontinue use and seek guidance from a medical professional

Comedogenic Rating

Rating: 1 / 5

Hydrolyzed Horse Placenta Extract is primarily made of small, water-soluble peptides and amino acids that do not leave a heavy residue on the skin. Because it lacks the rich oils or waxes known to block pores it earns a low comedogenic score of 1, meaning it is very unlikely to cause breakouts for most users. Those who are prone to acne can generally use products containing this extract without added concern, though overall formulation still matters. If the product also contains heavier emollients the risk of congestion may increase, so always check the full ingredient list.

Summary

Hydrolyzed Horse Placenta Extract works mainly as a skin-protecting agent. Its blend of peptides, amino acids, vitamins and minerals forms a light conditioning veil that reinforces the skin barrier, supports moisture retention and helps shield against day-to-day environmental stress. These benefits translate to a softer, more resilient and smoother-looking complexion.

The ingredient sits in a niche corner of skincare, appreciated in certain high-end anti-aging lines but less common in mainstream products due to sourcing costs and ethical preferences. For users comfortable with animal-derived components it offers a gentle yet effective way to bolster the skin’s defense system.

Current research and long-time cosmetic use suggest it is generally safe with low irritation potential when properly formulated. As with any new skincare ingredient it is wise to perform a patch test before full use to ensure personal compatibility.

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