Hydrolyzed Placental Extract: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Hydrolyzed Placental Extract?

Hydrolyzed Placental Extract is made from the placenta of healthy pigs that are raised for the food industry. After birth the placentas are collected, cleaned and broken down with gentle acids or natural enzymes. This process, called hydrolysis, chops large proteins into smaller peptides and free amino acids that skin can recognize and use. Along with these building blocks the extract also contains vitamins, minerals and trace growth factors that are naturally present in placental tissue.

The idea of using placental material in beauty care is not new. Early versions appeared in European skin creams in the 1950s and later gained popularity in East Asian sheet masks and essences. Modern methods focus on safety and purity, using controlled sourcing and pharmaceutical style filtration to remove unwanted particles while keeping the active components.

Once the liquid is filtered and sterilized it can be dried into a powder or kept as a concentrated solution. Formulators add it to anti aging serums, rich moisturizers, brightening lotions, eye creams and sheet masks where it can help refresh tired skin and support a smoother appearance.

Hydrolyzed Placental Extract’s Cosmetic Benefits/Uses

This ingredient is valued for one primary role in skincare formulas.

Skin conditioning: The mix of peptides and amino acids helps soften and hydrate the surface of the skin. By supporting the skin’s natural protein structure it can improve elasticity, give a firmer feel and promote a healthy looking glow.

Who Can Use Hydrolyzed Placental Extract

Most skin types can tolerate this ingredient. Normal, dry and mature skin often enjoy the hydrating and firming feel. Oily or acne-prone skin can still use it because the extract itself is lightweight, yet the finished product’s overall richness might be a better fit for night use only. Very sensitive skin should start slowly since animal proteins can occasionally prompt redness.

The extract is not suitable for vegans or vegetarians because it is sourced from porcine placenta, an animal by-product. People who avoid pork for cultural or religious reasons will also want to skip it.

Current data shows no direct risk for women who are pregnant or breastfeeding when the ingredient is used topically, yet this is not medical advice. Anyone expecting or nursing should ask their doctor before adding new skincare products to their routine.

Hydrolyzed Placental Extract does not make skin more prone to sunburn so it is not considered photosensitizing. It works well alongside broad spectrum sunscreen during the day.

Potential Side Effects/Adverse Reactions

Responses to topical Hydrolyzed Placental Extract vary from person to person. The following list covers potential but uncommon effects. When the product is made and used correctly most people will not notice any problems.

  • Redness or irritation in sensitive skin
  • Allergic reaction in individuals with pork allergies
  • Mild itching or stinging on first applications
  • Breakouts if the finished formula is too heavy for acne-prone skin
  • Discomfort with the scent if a natural meaty odor is not fully masked

If any discomfort, rash or swelling occurs stop using the product and seek medical advice.

Comedogenic Rating

Rating: 1/5

Hydrolyzed Placental Extract itself is a water soluble mixture of peptides and amino acids with very little oil or wax so it rarely clogs pores. Any breakouts people report usually come from richer emollients or occlusive agents that surround it in a finished cream, not from the extract. Because its own rating sits at 1 it is generally suitable for acne-prone or easily congested skin, though overall formula texture still matters. If the product feels heavy or greasy it may not be the best choice for those battling frequent blemishes.

Keep in mind that comedogenic scales are guides, not guarantees. Individual skin chemistry, climate and layering habits can all influence whether a pore gets blocked.

Summary

Hydrolyzed Placental Extract conditions the skin by delivering small proteins and amino acids that support collagen, improve elasticity and boost surface hydration. These molecules act like building blocks the skin can readily use, which translates to a softer, firmer and more radiant look.

Once a niche ingredient in European spa creams it is now moderately popular in Asian sheet masks and high end anti aging serums, yet it remains less common than familiar actives like hyaluronic acid or peptides from plants.

Topically, it shows a solid safety profile with low irritation risk for most users, though anyone with pork allergies, very reactive skin or ethical concerns should avoid it. As with any new skincare ingredient, patch test first to make sure your skin is happy before applying it to your whole face.

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