Hydrolyzed Silk Gland Extract: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Hydrolyzed Silk Gland Extract?

Hydrolyzed Silk Gland Extract comes from the silk glands of the silkworm, most often Bombyx mori. Inside these glands are proteins such as fibroin and sericin that give silk its famous strength and softness. When the raw gland material is broken down with water, enzymes or mild acids, the long protein chains split into much smaller peptides and amino acids. This process, called hydrolysis, creates a lightweight water-soluble ingredient that skin can readily absorb.

The beauty world first took notice of silk proteins in the 1990s after textile research showed that workers handling silk often had smooth hydrated hands. Laboratories soon adapted the textile processing methods to produce cosmetic-grade hydrolyzed extracts. Today manufacturers collect the glands left over from silk production, purify them, then run controlled hydrolysis to reach a targeted molecular weight that balances skin feel and performance.

Thanks to its ability to bind water and leave a soft finish, Hydrolyzed Silk Gland Extract appears in a range of formulas such as sheet masks, hydrating serums, lightweight lotions, eye creams, anti-aging concentrates, overnight masks and even hair conditioners.

Hydrolyzed Silk Gland Extract’s Cosmetic Benefits/Uses

In topical products this ingredient is prized for one primary role.

Humectant: The small peptides and amino acids attract and hold moisture from the environment or deeper skin layers, increasing overall hydration. This added water can make the complexion look plumper, soften the feel of rough patches, support a healthy skin barrier and give formulas a smooth silk-like glide that users enjoy during application.

Who Can Use Hydrolyzed Silk Gland Extract

This ingredient is gentle enough for most skin types. Dry and mature skin often sees the biggest boost because the silk peptides pull in extra water, while oily and combination skin enjoy the lightweight feel that does not add grease. Sensitive skin usually tolerates it well, though anyone with a known silk or insect allergy should avoid it in case of cross reaction.

Because Hydrolyzed Silk Gland Extract comes from silkworms it is not considered vegan and some vegetarians may choose to skip it. Shoppers who follow a strict plant based lifestyle should look for a plant derived humectant instead.

No research shows that the ingredient poses a special risk to women who are pregnant or breastfeeding when used on intact skin. This is not medical advice and anyone expecting or nursing should show their routine to a qualified doctor to be safe.

The extract does not make skin more sensitive to the sun, so it is fine for daytime use. It also plays well with common actives such as vitamin C and niacinamide, making it an easy add-in to almost any regimen.

Potential Side Effects/Adverse Reactions

Reactions to Hydrolyzed Silk Gland Extract differ from person to person. The points below list potential issues, but most people who use products formulated correctly will not notice any problems.

  • Allergic contact dermatitis – rare itchiness, redness or swelling in people allergic to silk proteins
  • Mild stinging on broken or freshly exfoliated skin – short lived and usually subsides quickly
  • Eye irritation – possible if a high concentration serum drips into the eyes
  • Protein cross sensitivity – very uncommon flare-ups in users already reactive to other insect derived ingredients

If any discomfort, rash or lingering redness occurs stop use at once and consult a healthcare professional.

Comedogenic Rating

Rating: 1/5

Hydrolyzed Silk Gland Extract is a water-soluble humectant that does not leave an oily film or clog pores. Its small peptides rinse away easily and do not build up on the skin surface, which is why formulators consider it very low risk for causing blackheads or pimples.

Suitability for acne-prone skin: Generally safe for those prone to breakouts, especially when used in lightweight gels or serums.

Because its main job is moisture binding, any breakouts that occur are more likely due to other richer ingredients in the product rather than the silk extract itself.

Summary

Hydrolyzed Silk Gland Extract works primarily as a humectant, drawing water into the skin with its tiny peptides and amino acids. This hydration plumps fine lines, softens rough spots and gives formulas a smooth glide that users enjoy. While not as famous as hyaluronic acid or glycerin, it has carved out a steady spot in sheet masks, serums and elegant lotions for people who like a lightweight silky feel.

The ingredient is considered very safe for topical use with only rare allergy concerns. As with any new product it is wise to perform a quick patch test to make sure your skin agrees with it.

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