Hydrolyzed Sodium Hyaluronate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
Share:
Inside this article:

We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Hydrolyzed Sodium Hyaluronate?

Hydrolyzed Sodium Hyaluronate is a smaller, broken-down form of sodium hyaluronate, itself the salt version of the well-known hydrator hyaluronic acid. Most commercial material starts with plant-sourced glucose that is fermented by friendly bacteria to make high molecular weight hyaluronic acid. This acid is converted to sodium hyaluronate for stability, then carefully treated with acid or enzymes so the long chains split into shorter fragments. The result is a fine, water-soluble powder that keeps the moisture-binding power of the original molecule but in sizes better able to slip between skin cells.

Hyaluronic acid entered skincare in the late 1980s as a premium hydrator. Over time chemists learned that large molecules sit on the surface while smaller ones can travel a bit deeper, leading to the development of hydrolyzed grades in the early 2000s. Because it is gentler, clear and almost weightless it quickly became a favorite for modern formulas that aim for a light feel.

You will spot Hydrolyzed Sodium Hyaluronate in a wide range of leave-on products such as facial serums, sheet masks, daily moisturizers, anti aging creams, eye gels, after-sun lotions and even some hair conditioners where extra moisture is welcome.

Hydrolyzed Sodium Hyaluronate’s Cosmetic Benefits/Uses

This ingredient is prized for its ability to condition the skin, helping formulas deliver an instant and lasting sense of hydration.

As a skin-conditioning agent it binds water like a sponge, drawing it to the skin surface and holding it there. This added moisture makes skin feel softer and look smoother, temporarily plumps the look of fine lines and supports a healthy barrier. Because the hydrolyzed version is lightweight it absorbs quickly without leaving a sticky film, making it ideal for layering with other products and suitable for both oily and dry skin types.

Who Can Use Hydrolyzed Sodium Hyaluronate

Because it is lightweight and non greasy this humectant suits nearly every skin type including oily, combination, dry and sensitive skin. It does not clog pores or add oil so acne prone users generally tolerate it well. There are no known skin types that should avoid it outright unless a rare personal allergy exists.

The raw material is created through bacterial fermentation of plant sourced sugars rather than from animal tissue which makes it acceptable for vegans and vegetarians.

Current safety data shows no reason pregnant or breastfeeding women cannot use it in topical products, yet this is not medical advice and anyone expecting or nursing should check with a doctor before adding new skincare just to be safe.

Hydrolyzed Sodium Hyaluronate is not known to increase photosensitivity so there is no special need for extra sun precautions beyond your usual daily sunscreen.

It pairs well with most other skincare ingredients such as vitamin C, niacinamide and retinoids making it easy to slot into almost any routine.

Potential Side Effects/Adverse Reactions

Reactions to topical Hydrolyzed Sodium Hyaluronate vary from person to person. The points below list potential issues but most users will not experience them when the ingredient is used correctly in a well formulated product.

  • Temporary redness or stinging – very sensitive skin may feel a brief flush as water movement in the skin changes
  • Allergic contact dermatitis – an uncommon immune response that can lead to itching swelling or rash
  • Increased transepidermal water loss in very dry climates – if ambient humidity is extremely low the molecule may draw water from deeper layers rather than the air potentially leaving skin feeling tight

If any persistent irritation or discomfort occurs stop use and consult a healthcare professional.

Comedogenic Rating

Rating: 0 / 5. Hydrolyzed Sodium Hyaluronate is a water-soluble humectant that does not contain oils or waxes, so it has no tendency to block pores or trap sebum. Its molecular structure attracts and holds water rather than forming an occlusive film, which keeps follicles clear.

Because of this, it is generally considered safe for skin prone to acne and breakouts.

Comedogenicity can rise or fall depending on the full formula, so pore-clogging risks come more from the other ingredients or an overly heavy texture than from the hyaluronate itself.

Summary

Hydrolyzed Sodium Hyaluronate is mainly used to condition skin by binding moisture, boosting surface hydration and giving a quick plumping effect that softens fine lines. Its smaller size helps it settle comfortably between skin cells and absorb without stickiness.

The ingredient is popular in modern skincare because it delivers a lightweight hydrating feel that suits nearly every skin type, showing up in everything from budget serums to luxury creams.

Current research and decades of use point to a very safe profile with low risk of irritation or allergy for most people. Still, whenever you try a new product containing Hydrolyzed Sodium Hyaluronate it is smart to patch test first so you can spot any unexpected reaction before applying it to your whole face.

Was this article helpful?
More from Glooshi:
ADVERTISEMENT
Get all our top headlines in beauty.
Delivered right to your inbox each week. Zero spam, all goodness, opt-out at anytime.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Get the latest beauty news, top product recommendations & brand-exclusive discount codes direct to your inbox.
Send good feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Send bad feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Search