Hydroxyceteth-60: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Hydroxyceteth-60?

Hydroxyceteth-60 is a synthetic, water-soluble ingredient created by attaching approximately 60 units of ethylene oxide to a fatty alcohol derived from cetyl alcohol. The resulting compound is a large, flexible molecule with both oil-loving and water-loving sections, which lets it interact easily with skin oils and rinse away with water. First explored in the late 20th century as formulators searched for milder alternatives to traditional soaps, it quickly found a place in personal care because it cleans effectively without leaving skin tight or dry. Production begins with plant- or petroleum-sourced cetyl alcohol that is reacted with ethylene oxide under controlled heat and pressure. This process, called ethoxylation, is carefully monitored to reach an average of 60 ethylene oxide units, giving the ingredient its characteristic balance of solubility and mildness. You will most often see Hydroxyceteth-60 in facial cleansers, micellar waters, makeup-removing wipes, baby washes and some hydrating body washes where a gentle yet thorough cleanse is needed.

Hydroxyceteth-60’s Cosmetic Benefits/Uses

Formulators turn to Hydroxyceteth-60 mainly for its cleansing ability. Its dual affinity for oil and water lifts away dirt, sunscreen and makeup then helps them rinse off easily with water. Because it is milder than many sulfate-based surfactants it supports formulas aimed at sensitive or dry skin, leaving the skin feeling soft instead of stripped.

Who Can Use Hydroxyceteth-60

Hydroxyceteth-60 is generally well tolerated by all skin types including oily, combination, normal and dry because its cleansing action is both effective and mild. Sensitive skin typically handles it better than harsher sulfates, though extremely reactive skin should still monitor for irritation since any surfactant has the potential to disturb a fragile barrier.

The ingredient is synthetic and derived from plant or petroleum sources, not animals, so it is suitable for vegans and vegetarians. Formulators commonly pair it with other vegan-friendly components, though anyone following a strict lifestyle should check the finished product for animal-derived additives.

No specific concerns have been flagged for use during pregnancy or breastfeeding. Current safety assessments show low absorption through intact skin, so routine facial cleansers or body washes containing Hydroxyceteth-60 are considered low risk. This is not medical advice and pregnant or nursing individuals should review any skincare routine with a healthcare professional to be safe.

The molecule does not make skin more sensitive to sunlight so it is not classified as photosensitizing. It is also fragrance-free and non-volatile which limits airborne irritation in wash-off formulas.

Potential Side Effects/Adverse Reactions

Side effects from topical use of Hydroxyceteth-60 vary from person to person. The points below cover potential reactions but most users will not experience them when the ingredient is formulated and used correctly.

  • Mild skin dryness if the cleanser is left on too long or used excessively
  • Temporary redness or stinging in people with compromised or highly sensitive skin
  • Eye irritation if the product accidentally enters the eyes
  • Allergic contact dermatitis in rare cases where the individual is sensitive to ethoxylated surfactants
  • Potential exposure to trace 1,4-dioxane if manufacturing purification is inadequate

If any adverse reaction occurs discontinue use immediately and consult a healthcare professional.

Comedogenic Rating

Rating: 1 out of 5 – Hydroxyceteth-60 is highly water soluble and designed to rinse away cleanly, leaving little to no residue that could block pores. Its large molecular size further limits penetration into follicles, keeping the likelihood of clogging very low. This makes it generally suitable for people prone to acne or breakouts. Because it is almost always used in wash-off products its skin contact time is brief, which reduces any pore-clogging risk even more.

Summary

Hydroxyceteth-60 functions primarily as a mild cleansing agent. Its balanced oil-attracting and water-attracting structure lifts away grime, sunscreen and makeup then carries them off with the rinse water, all while helping skin feel soft rather than stripped. Although not as famous as sulfates or newer sulfate-free surfactants, it holds a steady place in gentle facial washes, micellar waters and baby cleansers thanks to its reliable performance.

Overall safety profiles rate Hydroxyceteth-60 as low risk, with minimal absorption through intact skin and a low irritation potential when properly formulated. Still, individual sensitivities vary, so it is always wise to patch test any new product containing this ingredient before adding it to a regular routine.

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