Hydroxypropyl Bisisostearamide Mea: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Hydroxypropyl Bisisostearamide Mea?

Hydroxypropyl Bisisostearamide Mea is a lab made ingredient created by linking two fatty acid molecules derived from isostearic acid with a small hydroxypropyl and ethanolamine backbone. This gives it the character of a soft, skin friendly oil yet it stays in a solid or semi solid form, which makes it handy for creams and balms. The compound first appeared in the late 1990s when formulators were looking for plant based substitutes for mineral oil thickeners. By using fatty acids that can be sourced from vegetable oils such as rapeseed or soybean, manufacturers built a more sustainable alternative that still delivers a silky feel. Production involves reacting purified isostearic acid with hydroxypropyl diamine, then neutralizing the mix with monoethanolamine to achieve the final amide structure. After purification the material is supplied as a waxy pellet or paste.

Thanks to its cushiony texture and high melting point, Hydroxypropyl Bisisostearamide Mea shows up in a range of leave on products. You will often see it in rich face moisturizers, all purpose body creams, lip balms, hand butters, overnight masks, anti aging serums, solid cleansing sticks and even some color cosmetics like cream blushes and foundations where it helps the formula glide smoothly.

Hydroxypropyl Bisisostearamide Mea’s Cosmetic Benefits/Uses

As an emollient Hydroxypropyl Bisisostearamide Mea softens skin by filling in tiny gaps on the surface, which leaves it feeling smooth and supple. It adds a pleasant slip during application, reduces moisture loss by forming a light barrier and enhances the luxurious feel of a product without making it greasy.

Who Can Use Hydroxypropyl Bisisostearamide Mea

Most skin types can enjoy this ingredient because it is a gentle fatty substance that mimics the skin’s own lipids. Dry and mature skin benefit the most from its cushioning feel while normal and combination skin can use it without feeling weighed down. Oily or very blemish prone skin may prefer lighter textures yet low use levels in a well balanced formula rarely cause extra shine.

The compound is typically produced from plant derived isostearic acid so it is suitable for vegetarians and vegans. As always those who follow a strict lifestyle should confirm the sourcing policy with the brand.

Current safety data does not flag Hydroxypropyl Bisisostearamide Mea as a concern for pregnant or breastfeeding women. This is not medical advice and anyone who is expecting or nursing should show the full ingredient list of any product to their doctor or midwife just to be on the safe side.

The ingredient does not make skin more sensitive to sunlight and has no known interactions with common actives like retinoids or acids. It is also fragrance free which helps minimize the risk of scent related sensitivity.

Potential Side Effects/Adverse Reactions

Side effects and reactions to the topical application of Hydroxypropyl Bisisostearamide Mea can vary from person to person. The points below outline potential issues yet they are unlikely to occur for the average user when the ingredient is formulated correctly.

  • Mild redness or stinging in people with highly reactive skin
  • Allergic contact dermatitis in the rare case of a specific sensitivity to fatty amides
  • Clogged pores or small breakouts if used in very heavy formulas on acne prone skin
  • Temporary eye irritation if the product accidentally gets into the eyes

If you experience any persistent discomfort discontinue use and seek advice from a healthcare professional or dermatologist.

Comedogenic Rating

Rating: 2 / 5

This low to moderate score reflects the ingredient’s fatty acid roots, which can theoretically sit on the skin and block pores, yet its bulky amide structure keeps it from penetrating deeply or feeling overly greasy. In most formulas it is used at low levels and is balanced with lighter emollients so it rarely causes problems for the average user.

Suitable for acne prone skin when included in lightweight or well balanced products, though very oily complexions may still prefer formulas that leave out richer waxes altogether.

Because it stays solid at room temperature it can build up if applied in heavy layers, so cleansing thoroughly at night helps avoid congestion.

Summary

Hydroxypropyl Bisisostearamide Mea is mainly an emollient that softens skin, boosts slip, reduces water loss and lends a rich, cushiony texture to creams balms and sticks. It does this by forming a thin, breathable lipid layer that mimics the skin’s own protective oils.

It is a niche but growing alternative to mineral oil thickeners, appreciated by formulators looking for plant derived ingredients that give a silky feel without greasiness.

Current safety data shows a very low risk of irritation or systemic toxicity, making it a dependable choice for most skin types. As with any new ingredient it is smart to patch test a product first to make sure your skin agrees with it.

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