Hylotelephium Cauticolum Callus Extract: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Hylotelephium Cauticolum Callus Extract?

Hylotelephium cauticolum is a hardy succulent often grown in rock gardens. Scientists learned that the plant’s callus tissue, the soft mass that forms when it repairs itself, is packed with moisture binding molecules and calming nutrients. By taking a small piece of the plant and growing it in a sterile culture, labs can create a steady supply of this tissue without harvesting whole plants. The cultured cells are then broken down with water or a gentle solvent and filtered, leaving a clear liquid known as Hylotelephium Cauticolum Callus Extract.

The extract is mainly made of natural sugars, amino acids and protective antioxidants that help skin hold water and stay comfortable. Because it is produced in controlled lab conditions, it is free from soil contaminants and seasonal changes, giving formulators a consistent ingredient every batch.

You will spot this extract in hydrating sheet masks, lightweight serums, daily moisturizers, after sun gels and many anti aging creams where long lasting hydration and a soothing feel are key selling points.

Hylotelephium Cauticolum Callus Extract’s Cosmetic Benefits/Uses

This plant based extract brings two main benefits to skin care formulas:

  • Humectant – pulls water from the air and the deeper layers of the skin to the surface so skin feels soft, plump and fresh for hours
  • Skin Conditioning – supplies nutrients that support a smooth surface, ease tightness and leave skin looking healthier overall

Who Can Use Hylotelephium Cauticolum Callus Extract

This ingredient is gentle enough for all skin types. Dry and mature skin appreciate its humectant punch while sensitive skin often tolerates it thanks to the low irritation profile of cultured plant cells. Oily or acne-prone users can also reach for it because it is lightweight and water based rather than oily or waxy.

Hylotelephium Cauticolum Callus Extract is grown entirely from plant cells in a sterile lab so it contains no animal input. That makes it suitable for both vegans and vegetarians.

No data points to risks for pregnant or breastfeeding women when the extract is used topically. It does not penetrate deeply or act hormonally, still this is not medical advice and anyone who is pregnant or nursing should clear any new skincare product with their doctor to be on the safe side.

The extract is not known to cause photosensitivity, so it can be used both day and night without increasing the skin’s sensitivity to sunlight.

Potential Side Effects/Adverse Reactions

Reactions to topical Hylotelephium Cauticolum Callus Extract vary from person to person. The issues listed below are only potential side effects and are highly unlikely to occur for the average user when the ingredient is formulated and preserved correctly.

Skin redness or flushing – a temporary warm look that subsides after rinsing

Mild itching or tingling – usually linked to very sensitive skin or overuse of multiple active products

Allergic contact dermatitis – rare but possible in individuals allergic to succulent plant proteins

Eye irritation – if the product accidentally gets into the eyes during application

If any of these effects appear stop using the product and consult a healthcare professional if symptoms persist or worsen.

Comedogenic Rating

Rating: 0 / 5

This extract is purely water based with no oily or waxy fractions, so it does not leave an occlusive film that can trap dead cells or sebum inside pores. Its key molecules are lightweight humectants that draw in moisture then evaporate or bind water within the upper layers of skin. Because the callus is grown in a controlled, sterile environment, there are no soil residues or heavy contaminants that could add to pore blockage.

For these reasons it is considered suitable for acne-prone or breakout-prone skin.

Keep in mind overall formula matters: if the product also contains rich plant oils or thick silicones pore clogging potential can rise even when this extract itself is non-comedogenic.

Summary

Hylotelephium Cauticolum Callus Extract works as a humectant and skin conditioning agent. Its natural sugars and amino acids pull water toward the surface while antioxidants and small peptides help keep the skin barrier calm and flexible. The result is a plumper, smoother feel that lasts beyond initial application.

The ingredient is still a niche addition so you will mostly find it in newer K-beauty hydrators, after sun gels and a handful of indie serums. As awareness of lab-grown botanical extracts spreads its presence is expected to grow.

Safety data show a very low risk of irritation or allergy and the extract is considered non-comedogenic, vegan friendly and pregnancy safe. Even so everyone’s skin is unique so it is smart to patch test any new product that contains it before applying over a larger area.

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