Isobutyroyl C10-40 Hydroxyacid C10-40 Isoalkyl Esters: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Isobutyroyl C10-40 Hydroxyacid C10-40 Isoalkyl Esters?

Isobutyroyl C10-40 Hydroxyacid C10-40 Isoalkyl Esters is a lab-crafted blend of long-chain fatty acids that have been linked to isobutyric acid. The result is a silky ester that behaves like a lightweight oil. Because these fatty chains range from 10 to 40 carbons, the ingredient offers both spreadability and a soft, cushiony feel on skin.

Although the compound itself is modern, the idea behind it grew from the cosmetic industry’s long-standing use of fatty acid esters to mimic skin’s own lipids. Chemists began pairing isobutyric acid with mid- to long-chain fatty acids in the early 2000s to improve texture without relying on heavier plant oils. The ingredient is produced through esterification: purified fatty acids from vegetable sources react with isobutyric acid under controlled heat then are filtered to remove any impurities. The finished material is clear, odorless and stable, making it easy to add near the end of a formulation.

You’ll most often spot Isobutyroyl C10-40 Hydroxyacid C10-40 Isoalkyl Esters in products that aim to leave skin feeling soft and supple. These include daily moisturizers, night creams, facial masks, anti-aging serums, body lotions, lightweight sun care bases and even some hair conditioners where extra slip is desired.

Isobutyroyl C10-40 Hydroxyacid C10-40 Isoalkyl Esters’s Cosmetic Benefits/Uses

In formulas this ingredient is classified as a skin conditioning agent, meaning it helps keep the skin surface smooth, hydrated and comfortable. Its silky texture creates a breathable film that reduces moisture loss, improves spreadability of the product and leaves a soft non-greasy finish that many people find pleasant for daily wear.

Who Can Use Isobutyroyl C10-40 Hydroxyacid C10-40 Isoalkyl Esters

This silky ester is generally suitable for most skin types. Dry and normal skin tend to benefit the most from its moisture-locking film while combination and oily skin usually appreciate its lightweight feel that does not leave a heavy residue. Those who are extremely acne-prone should still monitor how their skin responds because any occlusive material, even a light one, can occasionally trap excess oil and debris.

The fatty acids used to create this ingredient are sourced from plants, not animals, so products containing it are typically vegan and vegetarian friendly. Brands can legitimately label such formulas cruelty free as long as no animal testing is involved elsewhere in the production chain.

Current safety data indicate no special restrictions for pregnant or breastfeeding individuals, but this information is not medical advice. Anyone who is expecting or nursing should run the full ingredient list of any cosmetic product past a qualified healthcare professional before adding it to a routine just to be safe.

Isobutyroyl C10-40 Hydroxyacid C10-40 Isoalkyl Esters is not known to increase photosensitivity, meaning it will not make skin more likely to burn in the sun. It also plays well with common active ingredients like retinol, vitamin C and chemical sunscreens so formulators often use it to improve texture without impacting efficacy.

Potential Side Effects/Adverse Reactions

Reactions to topical Isobutyroyl C10-40 Hydroxyacid C10-40 Isoalkyl Esters vary from person to person. The points below outline potential side effects only and most users will not experience them when the ingredient is used correctly in a well-formulated product.

Transient redness or warmth

Mild stinging on freshly exfoliated or compromised skin

Clogged pores in individuals who are very oily or acne-prone

Rare allergic contact dermatitis for those sensitive to isobutyric acid derivatives

If any of these reactions occur discontinue use at once and consult a healthcare professional for personalized guidance.

Comedogenic Rating

Rating: 2 out of 5 – Isobutyroyl C10-40 Hydroxyacid C10-40 Isoalkyl Esters is a lightweight ester that forms a soft breathable film rather than a thick occlusive barrier. Its branching (isoalkyl) structure keeps the molecule from packing tightly into pores, reducing the risk of blockages compared with heavier straight-chain oils. That said, the presence of mid- to long-chain fatty portions still gives it a mild potential to trap sebum in very oily skin. Overall it is considered low to moderate in pore-clogging likelihood, so most acne-prone users can tolerate it though highly reactive skin types might prefer a true non-comedogenic alternative. Extra factors such as formula concentration, presence of other rich emollients and individual skin chemistry will influence the final outcome.

Summary

Isobutyroyl C10-40 Hydroxyacid C10-40 Isoalkyl Esters acts primarily as a skin conditioning agent, lending slip, softness and a light occlusive veil that slows water loss. Its branched ester structure spreads easily, improves the sensory feel of creams and lotions and leaves a non-greasy finish while still reinforcing the skin’s lipid layer. Though not a headline ingredient it is gaining quiet popularity among formulators who want to replace heavier plant oils and silicones with something vegan friendly and biodegradable.

Current data show the ingredient is safe for topical use at the levels found in cosmetics with only rare reports of irritation or allergy. As with any new product it is smart to perform a patch test first to make sure your skin agrees with the full formula.

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