Isopropanolamine: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Isopropanolamine?

Isopropanolamine, also known as 1-aminopropan-2-ol, is a small water-soluble molecule that belongs to a group of ingredients called amino alcohols. Most of the supply used in cosmetics is made in labs, starting with propylene that is converted to propylene oxide then reacted with ammonia to form the amine-alcohol blend. Careful distillation separates the different grades so formulators can choose the purity and concentration they need.

First used in industrial cleaning products to help keep formulas stable, its gentle pH-balancing talent soon caught the eye of cosmetic chemists. As regulations for safer household and personal care products tightened in the 1980s and 1990s, companies looked for reliable pH adjusters with a good safety record. Isopropanolamine fit that role and has been a quiet workhorse in beauty labs ever since.

Today you can spot it on ingredient lists in many rinse-off and leave-on items. Common examples include facial cleansers, clay or cream masks, lightweight lotions, thicker creams, exfoliating toners, hair conditioners, shampoos and even a few styling gels. Whenever a formula needs its acidity gently nudged into the skin-friendly zone, isopropanolamine is one of the options a chemist might reach for.

Isopropanolamine’s Cosmetic Benefits/Uses

In skin and hair care formulas this ingredient has one main job that delivers several practical benefits.

Buffering: Isopropanolamine helps keep the product’s pH in the ideal range during manufacturing and throughout its shelf life. A stable pH protects delicate actives from breaking down, prevents irritation that can come from an overly acidic or alkaline product and supports the skin’s own acid mantle so the user enjoys consistent results from the first pump to the last.

Who Can Use Isopropanolamine

Because it is mainly a pH stabilizer rather than an active treatment, isopropanolamine is considered gentle enough for most skin types including dry, oily, combination and sensitive. People with highly compromised or broken skin should still proceed cautiously since even mild ingredients can sting when the barrier is damaged.

The ingredient used in cosmetics is produced synthetically from petrochemical sources so it contains no animal derived components. That makes it suitable for both vegans and vegetarians, provided the finished product is also certified cruelty free.

Current safety reviews have not flagged topical isopropanolamine as a concern for women who are pregnant or breastfeeding, but this is not medical advice. Anyone who is expecting or nursing should show the full ingredient list of their skincare products to a healthcare professional before use to be safe.

Isopropanolamine is not known to increase photosensitivity, so it will not make skin more prone to sunburn. Standard daytime sun protection is still recommended for overall skin health.

Potential Side Effects/Adverse Reactions

Reactions to topical isopropanolamine vary from person to person. The issues listed below are only potential side effects and are unlikely to occur for most users when the ingredient is formulated correctly.

  • Transient redness or tingling on very sensitive skin
  • Mild eye irritation if the product accidentally gets into the eyes
  • Rare allergic contact dermatitis marked by itching or small bumps
  • Slight dryness in hair when used in high concentrations in hair care products

If any of these effects occur discontinue use and consult a healthcare professional.

Comedogenic Rating

Rating: 0 – 1 (very low)

Isopropanolamine is fully water soluble so it does not linger on the skin surface or trap sebum inside pores. It functions as a pH buffer rather than an emollient or thickener and is used at small percentages, giving it practically no clogging potential.

Because of this it is generally considered safe for people who are prone to acne or regular breakouts.

No notable research or user reports link the ingredient to increased blackheads, whiteheads or cystic flare-ups, even in leave-on formulas.

Summary

Isopropanolamine is a lab-made amino alcohol that keeps cosmetic formulas in their target pH range. By buffering acidity it protects delicate actives, helps prevent irritation and supports the skin’s natural acid mantle. Although it is a quiet background player rather than a buzzworthy hero ingredient, its reliability keeps it in steady rotation in cleansers, masks, lotions and hair care.

Safety evaluations rate it as low-risk for the vast majority of users with only rare reports of mild irritation. As with any new skincare ingredient a quick patch test is a smart habit before applying a full-sized dose.

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