Lactobacillus/Barley Extract Ferment Extract Lysate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Lactobacillus/Barley Extract Ferment Extract Lysate?

Lactobacillus/Barley Extract Ferment Extract Lysate is a fermented skincare ingredient that comes from combining barley, a nutrient rich grain, with Lactobacillus, a type of probiotic bacteria often used to make yogurt. During a controlled fermentation process the bacteria break down the barley extract into smaller molecules, then the cells are gently lysed, or opened, to release a cocktail of peptides, amino acids and sugars that can benefit the skin. Fermented ingredients jumped into the spotlight in East Asian beauty labs during the 1990s and early 2000s as brands searched for milder, more bioavailable actives, and this lysate soon followed as formulators noticed its ability to soften and comfort stressed skin. To manufacture it, producers steep barley to draw out its natural compounds, add a starter culture of Lactobacillus, maintain a warm temperature for several hours or days, filter the liquid and finally use mechanical or enzymatic steps to burst the bacteria so their contents blend with the barley nutrients. The finished ingredient is a clear to pale amber liquid that slips easily into water based formulas. You will most often spot it in lightweight serums, sheet masks, calming creams, hydrating lotions, post shave balms and anti aging blends that focus on strengthening the skin barrier.

Lactobacillus/Barley Extract Ferment Extract Lysate’s Cosmetic Benefits/Uses

In beauty products Lactobacillus/Barley Extract Ferment Extract Lysate serves one core purpose: skin conditioning. By helping skin hold on to moisture and delivering soothing compounds it can improve softness, suppleness and overall comfort. Regular use may also support a stronger barrier, which in turn can make skin look smoother and more even toned.

Who Can Use Lactobacillus/Barley Extract Ferment Extract Lysate

This ferment filtrate is mild enough for dry, oily, combination and sensitive skin because it hydrates without leaving a heavy residue and it contains soothing by-products from the probiotic step. Most people tolerate it well yet anyone with a known barley or grain allergy should proceed carefully since trace proteins could linger in the extract. The ingredient is produced from barley and a plant-friendly strain of Lactobacillus so it is generally suitable for vegetarians and vegans, provided the final formula does not include beeswax, lanolin or other animal additives. As it is free of drug-level actives like retinoids or strong exfoliating acids women who are pregnant or breastfeeding can usually use it, but this is not medical advice and those individuals should show the full product list to their doctor before regular use. The lysate does not make skin more prone to sunburn and it pairs well with sunscreen and other daytime products.

Potential Side Effects/Adverse Reactions

Side effects from topical Lactobacillus/Barley Extract Ferment Extract Lysate vary from person to person. The points below outline potential issues yet most users will not notice any problems when the ingredient is included at an appropriate level in a well-made product.

Transient tingling or mild warmth upon application

Temporary redness or irritation in highly reactive skin

Allergic response in individuals sensitive to barley proteins or probiotic fragments

Rare clogged pores or breakouts if the overall formula is very rich and the user is acne-prone

Contamination-related infection if a DIY product lacks proper preservation

If any negative reaction occurs stop using the product and consult a healthcare professional or dermatologist.

Comedogenic Rating

Rating: 0 (non-comedogenic)

Lactobacillus/Barley Extract Ferment Extract Lysate is a thin water soluble liquid with no oily residues or waxes that could block pores. It is used at low concentrations and is rapidly absorbed, leaving little behind that acne-causing bacteria can feed on. As a result formulators consider it non-comedogenic.

Bottom line: generally safe for acne-prone skin.

Keep in mind the finished product matters; if the lysate is blended into a rich cream full of heavy butters the overall formula could still clog pores.

Summary

Lactobacillus/Barley Extract Ferment Extract Lysate is a fermented active that conditions skin by boosting moisture levels, calming irritation and reinforcing the barrier through a mix of peptides, amino acids and sugars produced during fermentation. It slips easily into serums, lotions and masks so brands use it to create gentle hydrating products.

While it is not the hottest buzzword on shelves it has a quiet following among formulators who want mild bioavailable ingredients that suit sensitive skin. You will often find it partnering with humectants like glycerin or hyaluronic acid to give an extra cushion of comfort.

Safety reviews show a low risk of irritation or clogging for most users, and it is considered pregnancy friendly. As with any new cosmetic it is wise to patch test a fresh product to rule out personal sensitivities before slathering it all over your face.

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