Lactulose: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Lactulose?

Lactulose is a sugary ingredient made from two natural sugars that come from milk: galactose and fructose. Chemists discovered it in the 1930s while studying dairy by-products, and it later found its way into skincare once experts noticed how well it holds water. Today most cosmetic-grade lactulose is produced by gently heating lactose with food-grade enzymes or acids, a process that rearranges the sugar bonds and creates this stable syrup-like molecule.

In cosmetic labs lactulose arrives as a clear to pale yellow liquid or a crystalline powder that dissolves easily in water. Formulators add it to leave-on and rinse-off products that need a surge of moisture such as sheet masks, hydrating serums, lightweight lotions, overnight creams and post-peel soothing gels. Because it is mild and non-irritating it also appears in sensitive-skin blends and baby care moisturizers.

Lactulose’s Cosmetic Benefits/Uses

When you spot lactulose on an ingredient list it is there to boost skin comfort and product feel. Its main roles are:

  • Humectant: Lactulose attracts water from the air and from deeper skin layers then locks it into the surface. This extra hydration plumps fine lines, smooths rough patches and gives skin a fresh, dewy look.
  • Skin conditioning: By keeping moisture levels balanced lactulose helps strengthen the outer skin barrier so it feels softer and less prone to flaking or tightness. It also improves the glide of creams and gels making them spread more evenly and absorb better.

Who Can Use Lactulose

Lactulose is gentle enough for most skin types including dry, normal, combination and oily. Its water-binding nature helps parched skin feel comfortable yet it is lightweight enough not to weigh down oilier complexions. Sensitive users usually tolerate it well since the molecule is non-acidic and free of common allergens.

Lactulose originates from milk sugars so standard cosmetic grades are not considered vegan. Vegetarians who consume dairy may be comfortable with it but strict vegans should look for products that clearly state the lactulose was produced by bacterial fermentation using plant-derived feedstocks, a newer though less common manufacturing route.

The ingredient is not known to interfere with pregnancy or breastfeeding when applied topically. That said this is not medical advice and anyone who is pregnant or nursing should have their doctor review any skincare routine to be safe.

Lactulose does not make skin more sensitive to sunlight and there are no special timing or SPF rules needed when using products that contain it.

Potential Side Effects/Adverse Reactions

Responses to topical lactulose can vary from person to person. The effects listed below are possible but uncommon when the ingredient is used correctly in a well-formulated product.

  • Mild stickiness
  • Transient tingling on very sensitive or compromised skin
  • Rare redness or itching in individuals with a sugar allergy or extreme sensitivity
  • Breakouts if layered with heavy occlusive products that trap sweat and oil

If you notice any persistent discomfort stop using the product and consult a healthcare professional or dermatologist.

Comedogenic Rating

Rating: 0

Lactulose is a small, fully water-soluble sugar that stays in the watery part of a formula rather than forming an oily film on skin. Because it neither blocks pores nor feeds acne bacteria it is classed as non-comedogenic.

As a result it is usually a safe choice for people who are prone to acne or breakouts.

Any clogging concerns are more likely to come from heavier oils, waxes or silicones included in the same product rather than from lactulose itself.

Summary

Lactulose works as a humectant and skin conditioner, drawing in moisture then holding it at the surface so skin looks plumper, smoother and more comfortable while improving the glide and absorption of the overall formula.

Though well known in the medical world its use in cosmetics is still relatively niche compared with staples like glycerin or hyaluronic acid, yet it offers formulators a gentle dairy derived alternative with strong water binding ability.

Topical safety data show a very low risk of irritation or allergy, but since every skin is different it is wise to patch test any new product that features lactulose before full application.

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