Lauryl Methyl Gluceth-10 Hydroxypropyldimonium Chloride: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Lauryl Methyl Gluceth-10 Hydroxypropyldimonium Chloride?

Lauryl Methyl Gluceth-10 Hydroxypropyldimonium Chloride is a plant-derived conditioning agent created by linking natural glucose to a lauryl chain, then adding ethylene oxide units and a quaternary ammonium group. The glucose often comes from corn or sugar beet while the lauryl part is sourced from coconut or palm kernel oil. Chemists began exploring sugar-based surfactants in the late 20th century as a gentler alternative to harsher cleansing and conditioning ingredients, and this molecule is one of the results. Production involves first methylating glucose, reacting it with ethylene oxide to reach an average of ten units, then attaching a lauryl dimethylamine and finally quaternizing the amine to give the positively charged chloride salt. That positive charge is what lets it bond to negatively charged hair surfaces, giving it its main benefits. You will most often see this ingredient in rinse-off and leave-on hair products such as shampoos, conditioners, masks, co-wash formulas and anti-frizz creams. It also appears in some body washes and gentle cleansing milks where added softness is desired.

Lauryl Methyl Gluceth-10 Hydroxypropyldimonium Chloride’s Cosmetic Benefits/Uses

This sugar-based quaternary compound offers two key functions that improve the performance and feel of many personal care formulas.

  • Antistatic – Its cationic charge neutralizes the static electricity that builds up on hair fibers. This helps reduce flyaways, improves combability and leaves hair looking smoother and more controlled.
  • Hair conditioning – The molecule forms a light film over each strand, locking in moisture and enhancing softness without heavy buildup. It can boost shine, make detangling easier and give hair a silkier touch.

Who Can Use Lauryl Methyl Gluceth-10 Hydroxypropyldimonium Chloride

Because this quaternary sugar derivative is mild and water soluble it suits most skin and hair types, including oily, balanced, dry and color-treated hair. People with very sensitive or allergy-prone skin may still prefer to scan ingredient lists for anything quaternary if they have reacted to similar conditioning agents in the past, but Lauryl Methyl Gluceth-10 Hydroxypropyldimonium Chloride is generally considered low risk.

The raw materials come from plant sources such as corn, sugar beet, coconut or palm so the ingredient itself is compatible with vegan and vegetarian lifestyles. Formulators may pair it with other animal-derived ingredients though, so anyone avoiding animal products should review the full label.

No specific warnings exist for pregnant or breastfeeding women using rinse-off or leave-on products that contain this ingredient. Still, this is not medical advice and those who are pregnant or nursing should run any new cosmetic routine past their doctor to be safe.

Lauryl Methyl Gluceth-10 Hydroxypropyldimonium Chloride does not absorb UV light or make skin more sun sensitive. It is also non-volatile so it will not contribute to inhalation issues during normal use. The ingredient is usually found at low concentrations, typically below 5%, which further supports its broad suitability.

Potential Side Effects/Adverse Reactions

Side effects from topical use of Lauryl Methyl Gluceth-10 Hydroxypropyldimonium Chloride vary from person to person. The points below outline potential issues, but most users will not experience them when the ingredient is formulated correctly and used as directed.

  • Mild skin or scalp irritation such as redness, itching or a stinging sensation
  • Allergic contact dermatitis in individuals already sensitized to quaternary ammonium compounds
  • Eye irritation if shampoo or conditioner accidentally gets into the eyes
  • Product buildup that can leave hair feeling heavy or greasy when used in very rich formulas without adequate rinsing

If you notice any of these effects stop using the product and seek advice from a healthcare professional or dermatologist.

Comedogenic Rating

Rating: 1/5. Lauryl Methyl Gluceth-10 Hydroxypropyldimonium Chloride is highly water soluble and designed to rinse away cleanly, leaving only a light conditioning film on hair rather than on facial skin. Its sugar backbone and quaternary structure make it far less likely to clog pores than oily or waxy emollients. Because it is usually present at low levels and primarily in hair products that are washed off, the chance of it trapping sebum or dead skin cells is minimal.

This low score means the ingredient is generally suitable for people prone to acne or breakouts. Only in rare cases where a very rich leave-on formula is applied directly to facial skin might congestion occur.

Summary

Lauryl Methyl Gluceth-10 Hydroxypropyldimonium Chloride acts mainly as an antistatic and hair conditioning agent. Its positive charge lets it cling to the negatively charged surface of hair, smoothing the cuticle, cutting down static and improving softness and shine. Because the molecule is partly derived from natural sugars and is water soluble, it delivers these benefits without a heavy or greasy feel.

The ingredient is moderately popular in modern hair care, especially in sulfate-free shampoos, co-washes and lightweight conditioners where formulators want gentle plant-based alternatives to traditional quats. It is less common in skin care but may pop up in creamy body washes for added slip.

Safety profiles rate it low risk with only occasional reports of mild irritation in sensitive individuals. As with any new cosmetic product it is wise to perform a quick patch test before full use to make sure your skin or scalp agrees with the formula.

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