Laurylglucosides Hydroxypropyltrimonium Chloride: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Laurylglucosides Hydroxypropyltrimonium Chloride?

Laurylglucosides Hydroxypropyltrimonium Chloride is a plant based ingredient created by joining a mild sugar derived cleanser called lauryl glucoside with a positively charged group known as a quaternary ammonium salt. The sugar part usually comes from renewable crops such as corn, wheat or potatoes while the fatty alcohol portion often comes from coconut or palm kernel oil. The finished molecule carries both water loving and oil loving parts, which lets it mix oils, dirt and water with ease.

Developers first explored sugar based surfactants in the 1990s when brands wanted gentler options than the sulfates used in earlier decades. Chemists later modified lauryl glucoside to include a conditioning “quat” head, giving us Laurylglucosides Hydroxypropyltrimonium Chloride. This tweak added extra softness on skin and hair without losing the original mildness, so the ingredient started showing up in shampoos and body washes in the early 2000s and has grown in popularity ever since.

The production process begins with fermenting plant sugars to form glucose units, then linking them to lauryl alcohol to make lauryl glucoside. This base is reacted with a small molecule that carries both hydroxyl and trimethylammonium groups, creating the final quaternized compound. Manufacturers favor this route because it keeps harsh solvents out and produces a biodegradable product.

You will find Laurylglucosides Hydroxypropyltrimonium Chloride in gentle shampoos, daily conditioners, sulfate free body washes, baby cleansers, micellar waters, makeup removing wipes, creamy face washes and leave on lotions aimed at sensitive or dry skin.

Laurylglucosides Hydroxypropyltrimonium Chloride’s Cosmetic Benefits/Uses

This multitasking ingredient offers two main benefits in personal care formulas

  • Skin Conditioning: The positive charge in the molecule is attracted to the negatively charged surface of skin and hair. It forms a light, smooth film that helps skin feel soft, reduces static on hair and boosts overall slip without heaviness.
  • Cleansing: Its sugar based surfactant backbone lifts away dirt, oil and makeup while staying gentle on the skin barrier. This makes it useful in cleansers meant for daily use or for people with easily irritated skin.

Who Can Use Laurylglucosides Hydroxypropyltrimonium Chloride

This gentle cleansing conditioner is generally suitable for all skin types including dry, sensitive, normal, combination and oily skin. Its mild nature helps preserve the skin barrier so even people who flush or sting easily often tolerate it well. Those with a known allergy to quaternary ammonium compounds or who need an ultra deep, squeaky-clean feel might prefer to avoid it or use it only in rinse-off products.

The ingredient is plant derived and does not rely on animal by-products so it fits vegan and vegetarian lifestyles. Most suppliers also avoid animal testing but if cruelty-free status is important it is best to check the finished brand’s policy.

Pregnant or breastfeeding women are not expected to face special risks because topical absorption is minimal and no hormonal action is known. This is not medical advice and anyone expecting or nursing should still show the full ingredient list to a qualified healthcare professional before use just to be safe.

Laurylglucosides Hydroxypropyltrimonium Chloride does not make skin more sensitive to sunlight and can be used both morning and night without changing your usual SPF habits.

Potential Side Effects/Adverse Reactions

Responses to any cosmetic ingredient vary from person to person. The points below outline potential side effects that have been reported in rare cases. When the ingredient is properly formulated most users will not notice any of these issues.

  • Mild skin irritation such as redness or a tight feeling
  • Temporary itching or burning if applied to broken skin
  • Eye stinging or watering when the product is accidentally rubbed into the eye area
  • Allergic contact dermatitis in individuals sensitive to quaternary ammonium compounds
  • Hair limpness or buildup when used in very high concentrations in leave-on products

If you notice any discomfort stop using the product and seek advice from a healthcare professional or pharmacist.

Comedogenic Rating

Rating: 1 out of 5

Laurylglucosides Hydroxypropyltrimonium Chloride is highly water soluble and rinses clean, so it does not linger on pores or leave an oily film. The slight conditioning layer it forms is breathable and lightweight, which keeps pore clogging risk very low, yet not quite zero because any film-forming agent can occasionally trap debris if used in heavy leave-on formulas.

The ingredient is generally suitable for acne-prone or breakout-prone skin.

Because it is usually used in rinse-off products and at modest levels, its comedogenic impact in real-world use is minimal.

Summary

Laurylglucosides Hydroxypropyltrimonium Chloride cleanses by lifting away oil and dirt with its sugar-based surfactant tail while its quaternary head lightly conditions skin and hair, leaving a soft feel. This dual action lets formulators replace harsher sulfates and separate conditioning agents with one plant derived molecule.

The ingredient has become a quiet workhorse in gentle shampoos, body washes and micellar waters, popular among brands aiming for mild sulfate-free labels though it is not yet a household name.

Safety data and user experience show it is low risk for irritation or clogged pores when properly formulated. As with any new product, a small patch test is wise to make sure your individual skin agrees with it.

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