Lysophosphatidylcholinylchlorin E6: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Lysophosphatidylcholinylchlorin E6?

Lysophosphatidylcholinylchlorin E6 is a lab crafted molecule that blends a lipid part, called lysophosphatidylcholine, with chlorin E6, a plant derived pigment related to chlorophyll. By merging the two, chemists created an ingredient that is oil compatible yet still carries the light sensitive and antioxidant traits of natural chlorins.

The idea of linking a chlorin to a skin friendly lipid surfaced in the late 2000s when researchers looked for gentler ways to manage excess oil on the skin while adding free-radical protection. Early studies showed that the hybrid stayed stable in creams and did not break down quickly when exposed to air or light, making it a good fit for everyday skincare.

Production starts with extracting chlorin E6 from plant matter such as spinach leaves. The pigment is purified then chemically attached to a lysophosphatidylcholine backbone sourced from soy or sunflower lecithin. The final compound is filtered, tested for purity and blended into a water-free concentrate that cosmetic labs can easily mix into formulas.

You will most often spot Lysophosphatidylcholinylchlorin E6 in clay or sheet masks aimed at shiny or breakout-prone skin, lightweight moisturizers for combination skin, anti-aging serums that promise antioxidant support and targeted T-zone treatments like blotting lotions and primers.

Lysophosphatidylcholinylchlorin E6’s Cosmetic Benefits/Uses

This multitasking ingredient offers two key actions that make it valuable in modern skincare.

  • Anti-Sebum – Helps balance the skin’s oil production so the face looks less shiny during the day. By keeping sebum in check it can reduce the risk of clogged pores and make makeup last longer.
  • Antioxidant – Neutralizes free radicals triggered by UV light and pollution which can cause dullness and early signs of aging. Regular use supports a healthier looking complexion and helps other sensitive ingredients stay stable in the formula.

Who Can Use Lysophosphatidylcholinylchlorin E6

The ingredient’s light, oil balancing nature makes it most appealing for normal, combination and oily skin. Dry or very sensitive types can still use it as part of a hydrating formula but may want to pair it with richer moisturizers since the sebum regulating effect could feel a bit tight if the skin is already short on oil.

Lysophosphatidylcholinylchlorin E6 is sourced from plant material so it fits vegan and vegetarian standards. The lipid portion comes from soy or sunflower lecithin and no animal by products are used during synthesis or purification.

Current data does not flag any specific concerns for people who are pregnant or breastfeeding. That said this is not medical advice and anyone expecting or nursing should review new skincare products with a qualified health professional before adding them to a routine.

The chlorin part of the molecule is naturally light sensitive but once bound to the lipid it becomes far less photo reactive. Everyday use has not been linked to heightened photosensitivity though wearing a daily sunscreen is still wise for overall skin health.

Potential Side Effects/Adverse Reactions

Responses to topical Lysophosphatidylcholinylchlorin E6 vary from person to person. The issues below are possible yet unlikely when the ingredient is formulated and used as intended.

  • Mild redness or warmth especially on very reactive skin during the first few uses
  • Temporary dryness if applied in high amounts on skin that is already low in oil
  • Rare photosensitivity in individuals with a history of light triggered reactions
  • Allergic contact dermatitis triggered by sensitivity to soy or sunflower derived lipids

Discontinue use and consult a healthcare professional if any persistent irritation or unusual reaction occurs

Comedogenic Rating

Rating: 1 / 5 – Lysophosphatidylcholinylchlorin E6 is carried by a lightweight phospholipid that sinks in quickly and does not linger as a heavy film. It helps curb excess oil rather than add to it and has shown little tendency to trap dead skin or debris in lab tests. Because the chlorin portion stays locked to the lipid it does not behave like a waxy pigment that could block pores.

This very low score means the ingredient is generally suitable for acne-prone or breakout-prone skin.

Keep in mind the full formula still matters. If the product pairs this molecule with rich butters or thick silicones overall pore-clogging risk can rise.

Summary

Lysophosphatidylcholinylchlorin E6 balances oil and shields skin from free radicals. The lipid end slips into the skin’s outer layer and signals sebaceous glands to ease up on sebum output while the chlorin end mops up reactive molecules formed by sunlight and pollution. Together these actions help keep shine down, pores clearer and early aging signs at bay.

It is a niche ingredient found mostly in modern K-beauty style masks, matte finish moisturizers and a handful of anti-aging serums though it has yet to hit the same popularity as niacinamide or vitamin C.

Current research and user feedback point to a strong safety profile with only rare reports of mild irritation. As with any new skincare step it is smart to run a quick patch test before full use just to be safe.

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