M-Hydroxyanisole: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is M-Hydroxyanisole?

M-Hydroxyanisole, also known as 3-methoxyphenol, is a small aromatic compound that comes from phenol, a simple plant-related molecule. By attaching a methoxy group to the third position on the phenol ring, chemists create M-Hydroxyanisole with a slight sweet scent and good stability. First explored in flavor and fragrance work, it found a place in cosmetics when formulators noticed its skin-friendly profile and mild antioxidant traits.

Today manufacturers produce it through controlled lab synthesis, starting with phenol and adding methanol in the presence of a catalyst. This route keeps purity high and ensures the final ingredient is free from unwanted residues.

M-Hydroxyanisole turns up in a range of topical products where a smooth feel and skin care boost are desired. You may spot it in leave-on moisturizers, anti-aging creams, sheet masks, soothing serums and specialty treatments aimed at improving overall skin texture.

M-Hydroxyanisole’s Cosmetic Benefits/Uses

The main reason formulators reach for M-Hydroxyanisole is its role as a skin-conditioning agent that helps products leave the skin softer and more supple. It supports the skin’s surface by enhancing moisture retention and promoting a comfortable feel, so the finished formula glides on easily and leaves a pleasant after-touch.

Who Can Use M-Hydroxyanisole

M-Hydroxyanisole suits most skin types including normal, dry, combination and oily because it is light and non-greasy. Sensitive skin usually tolerates it as well, though anyone with a known phenol allergy should stay cautious since the molecule is phenol-based.

The ingredient is made synthetically from simple lab chemicals, not animal-derived substances, so it is appropriate for vegans and vegetarians.

Current data does not flag M-Hydroxyanisole as harmful during pregnancy or breastfeeding when used in typical cosmetic amounts, but this is not medical advice. Expectant or nursing mothers should show any product containing it to their doctor before adding it to a routine.

M-Hydroxyanisole is not known to cause photosensitivity, so daytime use does not require extra sun precautions beyond a normal broad-spectrum sunscreen.

Potential Side Effects/Adverse Reactions

Responses to topical M-Hydroxyanisole differ from person to person. The points below outline potential side effects that could happen, yet most people will not run into these issues when the ingredient is properly formulated and used as directed.

  • Mild skin irritation
  • Temporary redness
  • Stinging or warmth right after application
  • Allergic contact dermatitis in those sensitive to phenolic compounds

If any of these reactions occur, stop using the product and consult a healthcare professional or dermatologist for guidance.

Comedogenic Rating

Rating: 0

M-Hydroxyanisole is a very small, lightweight molecule that does not form an occlusive film on the skin and has no oily or waxy residues, so it is highly unlikely to block pores. Because of this, it is generally suitable for people prone to acne or breakouts. No data suggest that it interferes with sebum flow or bacterial balance, further supporting its non-comedogenic status. Formulation context still matters since combining it with heavier butters or oils could change the overall pore-clogging potential of the finished product.

Summary

M-Hydroxyanisole acts mainly as a skin-conditioning ingredient, helping formulas keep the skin soft, smooth and comfortably hydrated. It achieves this by binding light moisture to the skin surface and improving the slip of the final product so it spreads evenly.

While not a headline ingredient, it appears in a modest number of moisturizers, serums and masks where formulators need a gentle conditioning agent that will not weigh down texture.

Current safety assessments show it is low risk when used at cosmetic levels with only rare reports of mild irritation or allergy. As with any new skincare addition, patch testing is a smart move to make sure your skin agrees with the product.

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