Maackiasin: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Maackiasin?

Maackiasin is a plant-derived polyphenol most commonly sourced from the bark and heartwood of the Maackia tree, a leguminous species native to East Asia. Chemically it belongs to the isoflavone family and features multiple hydroxyl groups that give it strong water-binding and antioxidant traits. The compound first drew attention in the 1990s when researchers studying traditional herbal extracts noticed its ability to hold moisture and guard against oxidative stress. Modern cosmetic labs obtain maackiasin either by gentle solvent extraction of sustainably harvested wood chips or through controlled synthesis that links phenolic building blocks in a sterile facility, a method that guarantees high purity and batch-to-batch consistency.

Because of its multitasking profile maackiasin appears in a range of leave-on products such as hydrating serums, sheet masks, anti-aging creams, after-sun lotions and barrier-repair treatments. Formulators value its stability in water-based systems and its compatibility with common emollients, making it easy to slot into both lightweight gels and richer emulsions.

Maackiasin’s Cosmetic Benefits/Uses

In formulations maackiasin performs several helpful roles

  • Humectant – its hydroxyl groups attract and bind water from the surrounding environment helping skin stay plump and comfortably hydrated throughout the day
  • Skin Conditioning – by enhancing the moisture content of the stratum corneum it leaves the surface feeling softer smoother and more supple which can improve the look of fine lines caused by dryness
  • Skin Protecting – its antioxidant activity helps neutralize free radicals generated by UV exposure pollution and daily stressors supporting the skin’s natural defense system and reducing signs of premature aging

Who Can Use Maackiasin

Maackiasin is gentle enough for most skin types. Dry and normal skins benefit from its strong water-holding ability while oily and combination skins appreciate that it hydrates without adding heavy oils. Because it is low on the irritation scale and contains soothing antioxidants, even sensitive skin usually tolerates it well. There are no known issues for darker skin tones or for people prone to hyperpigmentation.

The ingredient is sourced from plants or produced through fermentation so it is suitable for vegans and vegetarians, with no animal by-products involved at any stage of manufacturing.

Current research shows no specific risks for pregnant or breastfeeding women when maackiasin is used in typical cosmetic concentrations. That said this is not medical advice and anyone who is expecting or nursing should run new skincare products past a doctor to be safe.

Maackiasin does not make skin more sensitive to sunlight and has no known phototoxic properties. It also plays nicely with common actives like niacinamide and hyaluronic acid so formulators can layer it without worry.

Potential Side Effects/Adverse Reactions

Responses to topical maackiasin differ from person to person. The following points list potential side effects which are considered uncommon when the ingredient is used at standard cosmetic levels.

  • Mild redness or warmth at the application site
  • Temporary stinging or tingling, especially on compromised skin
  • Allergic contact dermatitis marked by itching or small bumps
  • Interaction with strong acids or retinoids that might amplify dryness in very reactive skin

If you experience any discomfort or unusual reaction stop using the product and seek advice from a healthcare professional.

Comedogenic Rating

Rating: 0–1

Maackiasin is a water-soluble polyphenol with no oily or waxy residues, so it does not linger in pores or create the kind of occlusive film that can trap sebum and debris. Its molecule is relatively small and breaks down readily in water-based formulas further reducing any clogging potential. Because of these characteristics it sits at the very bottom of the comedogenic scale.

Suitable for acne-prone or breakout-prone skin.

Most commercial formulations include Maackiasin at low concentrations alongside lightweight humectants which keeps the overall product texture non-greasy. Only when paired with highly occlusive carriers such as heavy butters could pore blockage become a remote concern and even then the culprit would likely be the carrier not Maackiasin itself.

Summary

Maackiasin works as a multitasking humectant skin-conditioning and skin-protecting agent. Its multiple hydroxyl groups latch onto water molecules to boost surface hydration while its antioxidant core scavenges free radicals helping defend the skin from environmental stress. This dual action leaves skin feeling soft smooth and resilient.

Although it is not a household name like hyaluronic acid its use is slowly growing in niche hydrating serums and barrier creams thanks to its clean plant origin and well-rounded benefits.

Current data shows Maackiasin to be low risk for irritation sensitization or pore blockage making it safe for most users including sensitive and acne-prone skin. As with any new skincare ingredient a simple patch test is wise to rule out personal sensitivities.

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