Methoxy Peg-113 Ascorbic Acid: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Methoxy Peg-113 Ascorbic Acid?

Methoxy Peg-113 Ascorbic Acid is a modified form of vitamin C in which a single methoxy polyethylene glycol chain containing 113 repeating units is linked to ascorbic acid. This pegylation shields the fragile vitamin C core from air and light, helping it stay potent longer while also making it freely soluble in water based formulas. The raw materials start with pharmaceutical grade ascorbic acid and a controlled length PEG polymer. Through a series of esterification and purification steps the two are joined, then the finished ingredient is filtered and dried into a fine white powder ready for cosmetic use.

Scientists began experimenting with pegylated vitamin C derivatives in the early 2000s when they noticed that traditional L-ascorbic acid lost activity quickly in creams and lotions. By attaching the PEG chain they created a more stable, easy to formulate antioxidant that could survive on store shelves and still deliver skin benefits. Since then Methoxy Peg-113 Ascorbic Acid has appeared in a growing number of products aimed at brightness and youthfulness.

You will most often spot it in water based serums, gel moisturizers, brightening masks, anti-aging creams, eye treatments and sheet masks where long term stability and a light feel are priorities.

Methoxy Peg-113 Ascorbic Acid’s Cosmetic Benefits/Uses

This versatile derivative offers several advantages in modern skincare formulas

  • Antioxidant: Helps neutralize environmental free radicals that can weaken collagen and trigger dullness so skin looks fresher and more resilient
  • Humectant: Draws and holds moisture on the skin’s surface boosting hydration levels and giving a soft supple feel without heaviness
  • Skin Conditioning: Supports a smoother touch and improved overall texture which can enhance the application and wear of makeup or other topical products

Who Can Use Methoxy Peg-113 Ascorbic Acid

This gentle vitamin C derivative is generally well tolerated by all skin types including oily, combination, normal and dry. Sensitive skin usually does fine because the pegylation softens the acidic punch of pure ascorbic acid yet anyone with a history of reacting to polyethylene glycol should proceed cautiously. Acne-prone users appreciate its non-greasy texture which hydrates lightly without clogging pores.

The ingredient is synthetic and does not rely on animal-derived components so it suits both vegans and vegetarians. Reputable suppliers also avoid animal testing making it a cruelty-free choice when sourcing policies are verified.

Current research shows no specific risks for pregnant or breastfeeding women when Methoxy Peg-113 Ascorbic Acid is applied topically at typical cosmetic levels. That said this information is not medical advice and individuals who are expecting or nursing should have their doctor review any skincare product they plan to use.

The molecule itself does not increase photosensitivity and can actually lend mild daytime antioxidant support when worn under sunscreen. Standard sun protection is still advised as part of any routine.

Potential Side Effects/Adverse Reactions

Responses to Methoxy Peg-113 Ascorbic Acid vary from person to person. The points below outline potential side effects yet most users experience none when the ingredient is correctly formulated and used as directed.

  • Mild tingling or transient stinging on application especially on compromised or freshly exfoliated skin
  • Temporary redness or warmth if the formula contains a high percentage of the derivative
  • Rare allergic contact dermatitis presenting as itching rash or swelling in those sensitive to PEG compounds
  • Potential enhanced irritation if layered with strong exfoliating acids or retinoids without adequate buffering time

If any persistent discomfort rash or swelling occurs discontinue use and seek guidance from a healthcare professional.

Comedogenic Rating

Rating: 0–1 (virtually non-comedogenic)

Methoxy Peg-113 Ascorbic Acid is a large water-soluble molecule that does not form an occlusive film or leave oily residue on the skin. Its polyethylene glycol backbone rinses clean and is readily diluted within lightweight serums so it has little tendency to lodge inside pores. Because of this it is considered safe for people who are prone to acne or breakouts. Formulation partners like silicones or rich oils could alter a finished product’s pore-clogging potential so the overall recipe still matters.

Summary

Methoxy Peg-113 Ascorbic Acid delivers three key actions: antioxidant protection by neutralising free radicals before they weaken collagen, humectant hydration by binding water to the skin’s surface and conditioning benefits that smooth texture for a softer feel. Pegylation keeps the vitamin C core stable in water-based formulas so it stays effective over time.

While not as famous as pure L-ascorbic acid or trendy derivatives like THD ascorbate this ingredient is gaining fans among formulators who want an easy-to-use vitamin C that remains potent on the shelf. Consumers will most often encounter it in modern serums masks and gel creams aimed at brightness and early anti-ageing care.

Topical use at cosmetic levels is viewed as very safe with low irritation risk for most skin types. As with any new skincare ingredient it is wise to perform a patch test before full-face application to confirm personal compatibility.

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