Methyl Glucose Dioleate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Methyl Glucose Dioleate?

Methyl Glucose Dioleate is a plant-derived ingredient created by attaching two molecules of oleic acid, a fatty acid from vegetable oils, to a methyl glucose backbone obtained from corn or sugar. The resulting compound, officially named D-Glucopyranoside methyl 2,6-dioleate, looks like a pale yellow viscous liquid that dissolves well in oils and disperses easily in water-based formulas. It first appeared in personal care labs in the late 1980s when chemists looked for gentler alternatives to mineral oil derivatives. Because its raw materials are renewable and its synthesis involves simple esterification steps under controlled heat and pressure, the ingredient quickly gained popularity with brands focused on mildness and sustainability. Today you can spot Methyl Glucose Dioleate in moisturizers, leave-on conditioners, cleansing balms, sheet masks, after-sun gels and many anti-aging creams where it helps keep skin soft and hydrated.

Methyl Glucose Dioleate’s Cosmetic Benefits/Uses

This multitasking ingredient improves both the feel and performance of many formulas.

  • Humectant: Attracts and binds water from the environment so the product delivers lasting hydration to skin or hair
  • Skin conditioning: Forms a light, flexible film that smooths rough spots and supports the skin barrier making the surface feel supple
  • Emollient: Adds slip and a velvety texture helping creams spread easily while reducing the greasy after-feel often linked to heavier oils

Who Can Use Methyl Glucose Dioleate

This ingredient is gentle enough for all skin types including dry, normal, combination and oily. Its light emollient film helps lock in moisture without feeling heavy which makes it a good pick for sensitive or easily irritated skin as well. Because it has a plant origin and does not contain animal by-products it is suitable for both vegans and vegetarians.

Pregnant or breastfeeding women can generally use products that contain Methyl Glucose Dioleate since no studies have linked it to hormone disruption or developmental harm. That said this is not medical advice and anyone who is expecting or nursing should ask a healthcare professional before starting new skincare just to be safe.

The ingredient does not make skin more likely to burn in the sun and it does not interfere with sunscreen filters. It also plays well with most other cosmetic actives so you will seldom run into layering issues.

Potential Side Effects/Adverse Reactions

Responses to topical Methyl Glucose Dioleate differ from person to person. The points below list potential issues that could appear though most people will not notice any of them when the ingredient is used at normal levels in a well-formulated product.

  • Mild skin irritation such as redness or stinging
  • Itching or tightness if the formula is heavily fragranced or contains other sensitizers
  • Rare allergic contact dermatitis for those with a specific sensitivity to sugar-derived esters
  • Clogged pores or small breakouts in individuals who are extremely acne prone and react to richer emollients

If you notice any of these reactions stop using the product and consult a healthcare provider or dermatologist for guidance

Comedogenic Rating

Rating: 1/5. Methyl Glucose Dioleate is a lightweight ester that sits mostly on the surface and has a branched structure that makes it harder to plug pores. It contains oleic acid chains, but they are bound to a sugar backbone which reduces their tendency to thicken inside follicles. Most people, even those with combination or oily skin, can use it without seeing extra blackheads or pimples.

Because its rating is so low, the ingredient is generally fine for acne-prone skin, though extremely reactive individuals may still prefer to stick with formulas labeled non-comedogenic.

Keep in mind that a final product’s pore-clogging risk depends on the full recipe, concentration and how often you apply it, so look at the whole ingredient list rather than focusing on one component.

Summary

Methyl Glucose Dioleate works as a humectant, skin conditioner and emollient. The sugar part attracts water and holds it against the skin, the twin oleic chains create a silky film that smooths rough patches and the overall molecule adds slip so creams spread easily without greasiness. Thanks to these multitasking skills and its plant origin, many brands focused on gentle or eco-minded formulas reach for it, although it is still less mainstream than household names like glycerin or shea butter.

Safety data show it is well tolerated with only rare irritation or allergy reports. It scores low on the comedogenic scale and has no known hormonal or photosensitivity issues. Still, everyone’s skin is different so perform a quick patch test when trying a new product that contains it to make sure it plays nicely with your complexion.

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