Myreth-3 Ethylhexanoate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Myreth-3 Ethylhexanoate?

Myreth-3 Ethylhexanoate is the cosmetic name for polyoxyethylene (3) myristyl ether octanoate, an ingredient created by joining a fatty alcohol from coconut or palm oil with ethylhexanoic acid and three small units of ethylene oxide. The result is a silky liquid that spreads easily on skin and mixes well with both water and oil. Chemists first explored this class of materials in the late 1960s when formulators wanted lighter feeling alternatives to heavy oils. Thanks to its smooth touch and quick absorption it soon found a place in lotions and creams.

The manufacturing process starts with myristyl alcohol, a fatty alcohol, that is reacted with ethylene oxide to add three “polyoxyethylene” links. This step boosts water compatibility. The modified alcohol is then esterified with ethylhexanoic acid to create the final ester. Each stage is done under controlled heat and vacuum to keep the product pure and colorless.

Today you will spot Myreth-3 Ethylhexanoate in many leave-on products such as everyday moisturizers, lightweight facial oils, body lotions, hand creams, after sun gels, anti-aging serums and even some wash-off masks and scrubs. Its ability to soften and smooth without a greasy feel makes it a favorite in formulas that promise fast absorption and a soft finish.

Myreth-3 Ethylhexanoate’s Cosmetic Benefits/Uses

Formulators reach for Myreth-3 Ethylhexanoate because it brings more than one useful property to the table.

  • Skin conditioning: It leaves a soft conditioned feel on the surface of the skin helping it look smoother and feel more supple after application
  • Emollient: It fills in tiny gaps between skin cells which reduces dryness flaking and rough texture while giving products a light non oily slip

Who Can Use Myreth-3 Ethylhexanoate

This lightweight ester suits most skin types including normal, dry, oily and combination because it delivers softness without a heavy oil film. People with sensitive or redness-prone skin usually tolerate it well since it contains no fragrance or strong actives that commonly trigger stinging, though individual responses can still vary. Acne-prone users often appreciate its low occlusive nature which helps limit pore congestion.

The raw materials come from plant oils so Myreth-3 Ethylhexanoate is generally considered suitable for vegans and vegetarians, provided the finished product has not been tested on animals and the manufacturer has confirmed plant sourcing.

No studies indicate special risks for women who are pregnant or breastfeeding when this ingredient is used topically in cosmetic amounts. That said this is not medical advice and anyone who is expecting or nursing should show any skincare product to a qualified healthcare provider before use.

The molecule does not make skin more sensitive to sunlight so it is not classed as photosensitising. It also has no known interactions with common cosmetic actives like retinol or vitamin C which means it can be layered freely in a routine.

Potential Side Effects/Adverse Reactions

Side effects and reactions to the topical application of Myreth-3 Ethylhexanoate can differ from person to person. The points below describe potential issues that could occur but they are uncommon when the ingredient is used at typical cosmetic levels.

  • Mild skin irritation such as temporary redness or itching especially on compromised or freshly exfoliated skin
  • Allergic contact dermatitis in individuals with a specific sensitivity to the ester or trace impurities
  • Transient eye stinging if the product accidentally gets into the eyes
  • Breakouts in very clog-prone skin when the overall formula contains multiple rich ingredients

If any of these effects occur stop using the product and consult a healthcare professional for personalised guidance.

Comedogenic Rating

Rating: 1 / 5 — Myreth-3 Ethylhexanoate is considered very low on the comedogenic scale because its small molecular size, partial water solubility and light texture make it unlikely to form a heavy film that traps oil and debris in pores. It spreads thinly, absorbs quickly and rinses away more easily than thicker plant butters or mineral oils, which keeps the chance of pore blockage minimal.

For most people prone to acne or breakouts this ingredient is generally acceptable, though overall formula composition and individual skin response still matter.

Keep in mind that comedogenic ratings are guides, not guarantees. A product loaded with several low-risk ingredients can still clog pores if used too often or layered with other rich products.

Summary

Myreth-3 Ethylhexanoate acts chiefly as a skin-conditioning agent and emollient. It slips between rough surface cells to smooth dry patches while leaving a barely there lipid layer that softens and helps prevent moisture loss. Its partial affinity for water also lets it blend seamlessly into lotions without making them feel greasy so skin is left silky instead of coated.

Though not as famous as jojoba oil or squalane this ester pops up in plenty of everyday moisturizers, hand creams and after sun gels because chemists value its light touch and compatibility with both aqueous and oily phases.

Safety profiles are strong: irritation or allergy is rare at cosmetic use levels and studies have not flagged any systemic concerns. Still, skin can be unpredictable so it is wise to patch test any new product featuring Myreth-3 Ethylhexanoate before full-face use.

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