What Is Myricetin?
Myricetin is a naturally occurring flavonoid found in many fruits, vegetables, teas and medicinal plants. Chemically identified as 3,3′,4,4′,5′,7-hexahydro-2-phenyl-4H-chromen-4-one, it belongs to the same family of plant pigments that give berries their rich colors and provide protective benefits to the plants themselves. Interest in myricetin dates back to traditional herbal remedies, but its strong antioxidant profile soon attracted modern skincare researchers who began adding purified forms to cosmetic formulas in the late 1990s.
Commercially, myricetin can be obtained in two main ways. The first is gentle solvent extraction from plant sources such as bayberry bark or red wine grapes followed by purification. The second is controlled laboratory synthesis that reproduces the natural molecule at high purity for consistent performance. Both routes yield a fine yellowish powder that easily dissolves into cosmetic bases.
You will most often see myricetin in antioxidant serums, age-defying moisturizers, brightening masks, eye creams and after-sun treatments where its protective and skin-soothing qualities are prized.
Myricetin’s Cosmetic Benefits/Uses
In skincare formulas myricetin delivers two key actions that help keep skin looking healthy and resilient.
- Antioxidant: Myricetin neutralizes free radicals generated by UV exposure and pollution, helping reduce the look of premature lines and uneven tone. By limiting oxidative stress it also supports the stability of other delicate ingredients such as vitamins C and E in the same product.
- Skin Conditioning: The molecule forms a light, breathable layer that leaves skin feeling smoother and better hydrated. Regular use can improve softness and give a more supple appearance which is especially beneficial in dry or mature skin products.
Who Can Use Myricetin
Because myricetin is lightweight and non-greasy it suits most skin types including oily, combination, normal and dry complexions. Sensitive skin generally tolerates it well thanks to its soothing nature, though anyone with a known allergy to plant flavonoids should proceed with caution.
The ingredient is sourced from plants or produced synthetically without animal derivatives, making it appropriate for vegans and vegetarians.
Current research shows no specific concerns for topical use during pregnancy or while breastfeeding, but this is not medical advice and anyone expecting or nursing should confirm product choices with a qualified healthcare professional to be safe.
Myricetin does not trigger photosensitivity so daytime use is fine when paired with your usual sunscreen. It also layers comfortably under make-up and other active treatments, giving formulators flexibility in different product types.
Potential Side Effects/Adverse Reactions
Responses to topical myricetin vary from person to person. The points below outline potential but uncommon side effects that could appear even when the ingredient is used correctly in a well-formulated product.
- Mild redness or stinging on very sensitive skin
- Temporary dryness if combined with multiple exfoliating acids
- Allergic contact dermatitis in individuals allergic to flavonoids or certain botanicals
- Possible interaction with copper peptides that may reduce the effectiveness of either ingredient when layered together
If any of these reactions occur stop using the product and consult a healthcare professional for guidance.
Comedogenic Rating
Rating: 0 (non-comedogenic). Myricetin is a small, water-dispersible flavonoid that does not clog pores or leave an occlusive film, so it is unlikely to trap oil or debris that could trigger breakouts. It is therefore considered suitable for acne-prone or congestion-prone skin. As with any ingredient, the overall formula matters; if myricetin is delivered in a heavy butter or wax the finished product could still feel pore-clogging even though the antioxidant itself is not.
Summary
Myricetin acts mainly as an antioxidant and a skin-conditioning agent. It scavenges free radicals created by sun exposure and pollution which helps keep collagen intact and supports a brighter even tone. At the same time it forms a light protective layer that leaves skin feeling softer and better hydrated without heaviness.
While it is not yet a household name like vitamin C or retinol, interest in plant-based antioxidants keeps growing and myricetin is steadily appearing in more serums eye creams and after-sun gels. Most users tolerate it well with few reports of irritation or sensitivity.
Overall myricetin is considered safe for topical use across skin types. Still, everyone’s skin is unique so it is wise to perform a quick patch test when trying any new product that contains this ingredient just to be sure your skin agrees with it.