Nicotinyl Tartrate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Nicotinyl Tartrate?

Nicotinyl Tartrate is a synthetic compound formed by combining nicotinic acid derivatives with tartaric acid, resulting in the salt known chemically as 3-Hydroxypyridinium hydrogen [R-(R*,R*)]-tartrate. The nicotinyl part comes from vitamin B3’s pyridine ring while the tartrate portion is naturally present in many fruits such as grapes. First explored in the mid-20th century for its potential to improve skin feel, it gained traction when formulators noticed its ability to support a smoother complexion without the irritation sometimes linked to plain niacin.

Production starts with fermenting or chemically synthesizing nicotinic acid, which is then reacted with purified tartaric acid under controlled pH and temperature. The resulting crystalline salt is filtered, dried and milled to a fine powder that dissolves easily in water-based cosmetic bases.

Today you can spot Nicotinyl Tartrate in lightweight moisturizers, anti-aging serums, sheet masks and brightening essences. Its compatibility with other common actives makes it a flexible choice for leave-on and rinse-off products aimed at boosting skin softness and radiance.

Nicotinyl Tartrate’s Cosmetic Benefits/Uses

In skincare formulas Nicotinyl Tartrate is valued for one key role

Skin conditioning: This ingredient helps the skin surface feel smoother and more supple by supporting the natural moisture barrier. Regular use can make the complexion look fresher and better hydrated which is why it often features in products that promise a healthy glow.

Who Can Use Nicotinyl Tartrate

Nicotinyl Tartrate is generally well tolerated by most skin types including dry, normal and combination skin. Oily and breakout-prone users can also benefit because the ingredient itself is lightweight and water soluble so it will not leave a greasy film that might clog pores. Those with very sensitive or highly reactive skin should proceed with a bit more caution since any niacin-based material can sometimes trigger temporary warmth or redness.

The compound is made entirely from synthetic or plant-derived sources so it is suitable for both vegans and vegetarians. No animal-derived raw materials or by-products are used during its manufacture.

Available safety data suggest that topical Nicotinyl Tartrate poses minimal risk during pregnancy or while breastfeeding. Still, this is not medical advice and anyone who is pregnant or nursing should check with a healthcare provider before adding new skincare products that contain this ingredient.

Nicotinyl Tartrate does not increase photosensitivity, meaning it will not make skin more prone to sunburn. Standard daytime sun protection is still recommended as part of any routine. No other special usage restrictions are known at typical cosmetic concentrations.

Potential Side Effects/Adverse Reactions

Side effects from topical Nicotinyl Tartrate differ from person to person. The points below outline potential reactions, though most users will not experience them when the ingredient is used correctly in a well-formulated product.

  • Transient flushing or warmth brief pinkness or a warming sensation, usually subsides within minutes
  • Mild tingling or stinging especially on freshly exfoliated skin or around delicate areas
  • Temporary redness more noticeable on fair complexions but generally short lived
  • Dryness or tightness if used in a high-strength formula without enough accompanying moisturizers
  • Irritation when layered with strong actives such as high-percentage acids or retinoids
  • Allergic contact dermatitis rare itching, swelling or rash in individuals sensitive to either niacin or tartrate components

Discontinue use and seek advice from a qualified healthcare professional if any of these effects occur or persist.

Comedogenic Rating

Rating: 0 / 5

Nicotinyl Tartrate is fully water soluble and leaves no oily residue so it does not have the fatty acids or waxes that typically block pores. Current literature and anecdotal reports show no pore clogging tendency which is why it earns a zero on the comedogenic scale.

This makes the ingredient suitable for people who are prone to acne or frequent breakouts.

Only if the final product pairs Nicotinyl Tartrate with heavy butters or occlusive silicones could pore clogging become a concern, in which case the overall formula rather than this single ingredient would be the culprit.

Summary

Nicotinyl Tartrate acts mainly as a skin-conditioning agent that helps the surface feel smoother and better hydrated by supporting the moisture barrier and enhancing overall suppleness. Its lightweight water-friendly profile lets it perform these tasks without greasiness so it fits well in serums, lotions and masks.

The ingredient is still a bit of a niche pick compared with big names like hyaluronic acid or niacinamide yet formulators appreciate its gentler take on niacin chemistry which is slowly boosting its presence in modern skincare lines.

Overall safety data are favorable with only mild transient flushing reported in a small percentage of users. While the risk of irritation is low it is always wise to patch test any new product to make sure your skin agrees with the full formula.

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