Nonyl Nonoxynol-15 Phosphate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Nonyl Nonoxynol-15 Phosphate?

Nonyl Nonoxynol-15 Phosphate is a lab made surfactant created by attaching about 15 units of ethylene oxide and a phosphate group to a dinonylphenol backbone. The result is an ingredient with a balanced mix of oil loving and water loving parts, which is what makes it useful in personal care formulas. It originated in the late twentieth century when chemists searched for gentler alternatives to soap based cleansers that could also stay stable in a wide range of products. Production begins with nonylphenol, which is reacted with ethylene oxide to build the polyoxyethylene chain. This intermediate is then treated with phosphoric acid to form the phosphate ester that improves rinsability and compatibility with skin friendly pH levels. Today you will spot Nonyl Nonoxynol-15 Phosphate in facial cleansers, micellar waters, makeup removers, body washes and some exfoliating masks where its mild yet effective cleansing power is prized.

Nonyl Nonoxynol-15 Phosphate’s Cosmetic Benefits/Uses

Formulators rely on this ingredient mainly for its cleansing ability.

As a cleansing agent, Nonyl Nonoxynol-15 Phosphate helps lift dirt, excess oil and makeup from the skin so they can be rinsed away with water. Its phosphate group makes it less harsh than traditional detergents, which helps maintain the skin’s natural moisture balance and reduces the chance of tightness after washing.

Who Can Use Nonyl Nonoxynol-15 Phosphate

This ingredient is generally well tolerated by normal, oily, combination and even dry or sensitive skin because its phosphate modification makes it milder than traditional detergents, though people with extremely reactive or allergy-prone skin may still prefer to avoid complex surfactant blends.

It is produced through a fully synthetic process that does not rely on animal derived raw materials, making it suitable for vegans and vegetarians who also verify the finished product’s cruelty free status.

Available data shows no specific risks for pregnant or breastfeeding women when the ingredient is used in rinse off amounts. This is not medical advice and anyone who is expecting or nursing should run their skincare routine past a doctor to stay on the safe side.

Nonyl Nonoxynol-15 Phosphate does not cause photosensitivity so it will not make skin more prone to sunburn.

The ingredient plays nicely with most actives, preservatives and fragrances so formulators can pair it with exfoliating acids, niacinamide or antioxidants without stability issues.

Potential Side Effects/Adverse Reactions

Reactions to topical Nonyl Nonoxynol-15 Phosphate can differ among individuals. The points below list potential but uncommon side effects, and most users will not experience them when the ingredient is correctly formulated in a product.

  • Mild skin irritation including redness, stinging or itching especially on sensitive skin
  • Transient dryness or a tight sensation if the formula is not rinsed off thoroughly
  • Eye irritation if the cleanser accidentally gets into the eyes
  • Rare cases of allergic contact dermatitis

If you experience any adverse reaction discontinue use and consult a healthcare professional if symptoms persist.

Comedogenic Rating

Rating: 1 / 5. Nonyl Nonoxynol-15 Phosphate is a water soluble surfactant that rinses off completely and leaves little to no residue, so it is highly unlikely to clog pores. The molecule is large and hydrophilic, meaning it prefers to stay in the water phase rather than settle into sebum-filled follicles where blackheads form. For these reasons it is generally suitable for acne-prone skin. Unless a formula is overloaded with heavy oils or waxes, the presence of this ingredient should not increase the risk of breakouts.

Summary

Nonyl Nonoxynol-15 Phosphate is a mild synthetic surfactant that loosens dirt, oil and makeup then helps them rinse away with water. Its phosphate group softens the cleansing action so skin feels fresh rather than stripped. You will mostly find it in face washes, micellar waters and makeup removers, though it has not reached superstar status and remains a niche choice compared with ubiquitous ingredients like sodium laureth sulfate.

Current research and decades of use point to a low risk profile with only rare irritation or allergy reports. As with any new skincare product it is wise to patch test first to confirm your skin is happy before applying it more widely.

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