Nonyl Nonoxynol-8 Phosphate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Nonyl Nonoxynol-8 Phosphate?

Nonyl Nonoxynol-8 Phosphate is a synthetic ingredient made by joining a nonylphenol base with about eight units of ethylene oxide, then attaching a phosphate group. This gives it a partly oily chain and a water-loving head so it can mix oil and water. It first appeared in industrial cleaners in the 1970s, and formulators later saw its gentle yet effective cleansing power as useful for personal care. Production starts with petrochemical feedstocks that are reacted to create nonylphenol, followed by controlled ethoxylation to add the eight oxyethylene units. The final step is phosphorylation, which improves water solubility and skin feel. Today you will find Nonyl Nonoxynol-8 Phosphate in facial cleansers, micellar waters, makeup-removing wipes, body washes, exfoliating masks and some shampoo formulas where a mild but thorough cleanse is needed without stripping skin or hair.

Nonyl Nonoxynol-8 Phosphate’s Cosmetic Benefits/Uses

This ingredient serves a single purpose in cosmetics: cleansing. Its balanced structure lifts dirt, oil and makeup while rinsing away easily, leaving skin comfortable rather than tight. Formulators like it because it works in both low and high water content products, tolerates a wide pH range and pairs well with other surfactants to boost overall performance.

Who Can Use Nonyl Nonoxynol-8 Phosphate

This mild cleanser suits most skin types including oily, combination, normal and even dry or mature skin thanks to its balanced oil-lifting yet non-stripping nature. Sensitive skin usually tolerates it well because it is less harsh than many sulfates, though anyone with a known allergy to nonylphenol ethoxylates should steer clear.

The ingredient is synthesized entirely from petrochemical feedstocks with no animal-derived components so it is considered vegan and vegetarian friendly.

No data link this surfactant to problems during pregnancy or while breastfeeding. Still, this is not medical advice and pregnant or nursing women should discuss any skincare product with their doctor for peace of mind.

Nonyl Nonoxynol-8 Phosphate does not make skin more prone to sunburn so it is not regarded as photosensitizing. It also rinses clean without leaving a residue that might interfere with other actives or cosmetics.

Potential Side Effects/Adverse Reactions

Reactions to topical Nonyl Nonoxynol-8 Phosphate differ from one person to another. The points below list potential issues yet they are uncommon when the ingredient is used at the low levels found in finished products.

  • Mild skin irritation
  • Transient redness or stinging on very sensitive skin
  • Eye irritation if product accidentally gets into the eyes
  • Allergic contact dermatitis in individuals already sensitized to related surfactants

If any discomfort or visible reaction occurs stop using the product and seek medical advice if symptoms persist or worsen.

Comedogenic Rating

Rating: 1 out of 5. Nonyl Nonoxynol-8 Phosphate is a rinse-off surfactant that breaks up oil then leaves the skin with minimal residue, so it rarely blocks pores. Its molecular size and high water solubility further lower the chance of buildup. Suitable for acne-prone and breakout-prone skin.

Because formulas may pair this ingredient with heavier emulsifiers or oils, the overall product could still vary in pore-clogging potential so always consider the full ingredient list.

Summary

Nonyl Nonoxynol-8 Phosphate is a synthetic cleansing agent that uses its oil-loving tail and water-loving phosphate head to lift dirt, makeup and excess sebum then rinse clean. It works across a wide pH range and blends well with other surfactants, giving formulators flexibility while keeping skin comfortable.

You will mostly see it in niche facial cleansers, micellar waters and makeup removers rather than in every drugstore wash, but brands that value mild non-sulfate options appreciate its performance.

Safety data show a low risk of irritation or sensitization at typical use levels, and there is no evidence of comedogenicity or photosensitivity. Still, skin is personal, so it is wise to patch test any new product that contains this ingredient before full use.

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