Octyldodeceth-25: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Octyldodeceth-25?

Octyldodeceth-25 is a nonionic surfactant created by attaching about 25 units of ethylene oxide to octyldodecanol, a fatty alcohol that can come from coconut, palm or laboratory synthesis. The result is a clear liquid that mixes easily with both water and oil.

Cosmetic chemists began using this ingredient in the 1980s when they were looking for gentler alternatives to older sulfate surfactants. Ethoxylated fatty alcohols like Octyldodeceth-25 offered the right balance of mildness and performance, so the material quickly found its way into skin and hair formulas.

The manufacturing process is straightforward: purified octyldodecanol is placed in a reactor, then ethylene oxide gas is added under pressure and heat. Each round of ethoxylation links another “peg” of ethylene oxide to the fatty alcohol until the desired chain length—about 25 units—is reached. After neutralization and filtration the product is ready for blending into cosmetic bases.

You will most often spot Octyldodeceth-25 in face washes, micellar waters, cream cleansers, sheet masks, moisturizers, lightweight serums, sunscreens, hair conditioners and color-depositing treatments. Its ability to clean gently while stabilizing emulsions lets formulators streamline their ingredient lists without sacrificing quality.

Octyldodeceth-25’s Cosmetic Benefits/Uses

In a formula Octyldodeceth-25 offers a couple of practical perks that improve both product feel and performance

  • Cleansing: Lowers the surface tension of water so it can spread across the skin or hair, grab onto dirt, excess oil and makeup then rinse them away without leaving a tight or squeaky after-feel
  • Emulsifying: Keeps water and oil phases blended into a uniform cream, lotion or gel which means the product stays smooth stable and pleasant to apply throughout its shelf life

Who Can Use Octyldodeceth-25

Because it is mild and nonionic Octyldodeceth-25 suits most skin types including dry, oily, combination and normal skin. Sensitive skin usually tolerates it well since it cleans without stripping natural oils, though anyone with a known surfactant allergy should be cautious.

The raw material can be sourced from plants like coconut or palm or made fully in the lab, so brands can offer a vegan and vegetarian friendly grade. If animal by-products matter to you check the label or the company’s sourcing statement for confirmation.

Current safety data show no issues for women who are pregnant or breastfeeding when the ingredient is used in rinse-off or leave-on cosmetics. This is not medical advice and anyone expecting or nursing should still let a health professional review their routine.

Octyldodeceth-25 does not increase photosensitivity, so it will not make skin more prone to sunburn.

Potential Side Effects/Adverse Reactions

Reactions to any cosmetic ingredient vary from person to person. The points below list potential side effects of topical Octyldodeceth-25 that most users will not experience when the product is formulated and used as intended.

  • Mild irritation or itching in very sensitive skin
  • Transient redness if applied to broken or compromised skin
  • Eye stinging if a cleanser containing the ingredient is not rinsed out fully
  • Rare allergic contact dermatitis in individuals already sensitized to ethoxylated compounds

If you notice persistent discomfort stop using the product and consult a healthcare professional

Comedogenic Rating

Octyldodeceth-25 has a comedogenic rating of 1 out of 5. The long polyethylene glycol chains make the molecule highly water friendly so it rinses off easily and does not form a heavy film inside pores. Although it starts from a fatty alcohol the ethoxylation step strips away most of the pore-clogging potential.

With such a low score it is generally fine for acne-prone skin though formulas that pair it with thick butters or waxes could still feel occlusive on very reactive complexions.

No studies link it to fungal acne flare ups so users managing malassezia concerns usually tolerate it.

Summary

Octyldodeceth-25 acts as a gentle cleanser and a dependable emulsifier. Its surfactant end grabs onto dirt and oil while water pulls everything away leaving skin comfortable. When blended into creams the same split personality keeps oil and water locked together so the texture stays smooth from the first pump to the last.

It is not the star of marketing campaigns yet you will find it quietly supporting countless cleansers moisturizers and sunscreens because chemists trust its mildness and reliability.

Decades of safe use and published data show a very low risk of irritation or toxicity. Still every skin is unique so patch test any new product that contains this ingredient to be sure it suits you.

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