What Is Oligopeptide-107?
Oligopeptide-107 is a lab crafted chain of 14 amino acids that include alanine, asparagine, glycine, histidine, isoleucine, leucine, serine and threonine. Because it is made synthetically, chemists can control its purity and performance from batch to batch, which is one reason brands like to use it. Peptide research took off in the late 1990s when scientists began looking for small protein fragments that could signal the skin to look and feel healthier. Oligopeptide-107 is one of the newer lab designed options to come out of that work, and it has steadily made its way into premium skincare lines.
To create it, manufacturers link the selected amino acids together in a specific order using solid phase peptide synthesis, a common method in cosmetic chemistry. After the chain is built, it is cleansed of by-products, tested for quality then blended into water based solutions so it can mix smoothly with creams and serums.
You are most likely to see Oligopeptide-107 in anti aging moisturizers, firming face masks, eye creams, lightweight serums and leave-on treatments that focus on improving skin texture.
Oligopeptide-107’s Cosmetic Benefits/Uses
In skincare formulas Oligopeptide-107 is prized for one key job.
As a skin conditioning ingredient it helps the surface of the skin feel soft and supple while supporting a smoother appearance over time. Brands often include it to give products an extra boost of hydration friendly comfort and to help the skin look more refined with consistent use.
Who Can Use Oligopeptide-107
Oligopeptide-107 is generally suitable for all skin types including dry, normal, combination and oily skin because it conditions the surface without leaving a heavy or greasy residue. Sensitive skin can usually tolerate it as well since peptides are small and tend to be gentle, though anyone extremely reactive to new ingredients should still proceed slowly. There are no known concerns for acne-prone skin because the molecule is lightweight and water soluble so it will not clog pores.
The peptide is made entirely in the lab from individual amino acids, not from animal tissue, which makes it appropriate for vegans and vegetarians. Its synthetic origin also means the purity can be tightly controlled, reducing the chance of trace animal by-products.
Current research has not flagged Oligopeptide-107 as a risk for women who are pregnant or breastfeeding. That said this is not medical advice and anyone expecting or nursing should always get personal guidance from a healthcare professional before adding new skincare to their routine.
The ingredient does not make skin more sensitive to sunlight, so it is not considered photosensitizing. Normal daily sun protection is still important to maintain overall skin health. No special storage or application cautions beyond standard clean, dry hands and avoiding the eye itself are required.
Potential Side Effects/Adverse Reactions
Responses to topical Oligopeptide-107 can differ from one person to another. The following list covers potential side effects that could occur, yet most users will not experience them when the ingredient is formulated and used correctly.
- Mild redness or warmth at the application site
- Temporary itching or tingling
- Localized dryness if the formula lacks adequate moisturizers
- Rare allergic reaction leading to swelling or hives
- Contact dermatitis in individuals with a specific peptide sensitivity
If any uncomfortable reaction develops discontinue use and consult a healthcare professional for advice.
Comedogenic Rating
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Oligopeptide-107 is a small, water-soluble molecule that leaves no oily film behind, so it does not block pores or trap debris. Its clean, lightweight profile keeps it firmly in the non-comedogenic category.
This makes it a safe pick for people who are prone to acne or frequent breakouts.
Since the peptide is usually blended into hydrating serums and creams rather than heavy balms, the finished products that use it also tend to remain low on the comedogenic scale.
Summary
Oligopeptide-107 is mainly valued as a skin-conditioning peptide that softens, smooths and supports a healthier-looking surface. It does this by pairing a carefully sequenced chain of amino acids with a water-friendly structure that can sit comfortably on the skin and boost formula performance.
While not yet as famous as collagen-boosting peptides like Matrixyl or Argireline, it is quietly gaining traction in mid to high-end skincare lines that focus on texture refinement and gentle anti-aging benefits.
Current data shows it is low risk for irritation, non-comedogenic and vegan friendly. Even so it is smart to patch test any new product that contains Oligopeptide-107 so you can make sure it plays well with your unique skin.