What Is Oligopeptide-167?
Oligopeptide-167 is a lab made chain of 22 amino acids that include familiar building blocks such as alanine, arginine, glycine and serine. Because it is synthesized rather than taken from animals or plants, it offers a consistent purity level and avoids supply issues tied to natural extracts. Chemists assemble the peptide through solid-phase synthesis, adding one amino acid at a time until the full sequence is complete, then purifying and stabilizing the final powder so it can be blended into skin care bases.
The beauty industry began exploring short peptides in the early 2000s for their ability to signal skin cells the way naturally occurring proteins do. Oligopeptide-167 entered cosmetic labs as researchers looked for options that could help guard skin from daily oxidative stress without relying on vitamins, which can be fragile or irritating. Today you will most often spot it in serums, lightweight moisturizers, anti-aging concentrates, sheet masks and eye treatments where a small dosage delivers antioxidant care without adding heaviness or scent.
Oligopeptide-167’s Cosmetic Benefits/Uses
In formulas Oligopeptide-167 serves a single, clear role.
As an antioxidant it helps neutralize free radicals produced by UV light, pollution and normal metabolism. By curbing these unstable molecules it supports a smoother, brighter complexion and may slow the appearance of fine lines that oxidative stress can speed up. Because the peptide is water soluble and effective at low levels, it fits easily into day or night products and pairs well with sunscreens and moisturizers to round out an everyday defense routine.
Who Can Use Oligopeptide-167
Because it is water based, lightweight and non comedogenic, Oligopeptide-167 suits dry, oily, combination and sensitive skin alike. It delivers antioxidant support without heavy oils or alcohol so even reactive complexions usually tolerate it. There are no specific skin types that must avoid the peptide, although anyone with a history of allergies to cosmetic peptides should approach with caution.
The peptide is produced entirely by chemical synthesis and contains no animal derived materials, making it suitable for both vegans and vegetarians.
Current research has not flagged Oligopeptide-167 as a concern for women who are pregnant or breastfeeding. That said, safety data is still limited, so this information is not medical advice. Expectant or nursing mothers should show the full ingredient list of any product to their doctor before use to be certain it is appropriate for their personal situation.
Oligopeptide-167 is not known to trigger photosensitivity, meaning it will not make skin more prone to sunburn. Standard daytime SPF use is still recommended to guard against general UV damage.
Potential Side Effects/Adverse Reactions
Responses to topical Oligopeptide-167 vary from person to person. The effects listed below are possible but uncommon when the ingredient is formulated and used correctly.
- Mild redness or warmth at the application site
- Temporary stinging or itching, especially on very sensitive skin
- Localized rash or hives indicating an allergic response
- Swelling around the eyes if the product migrates into the ocular area
- Contact dermatitis in individuals with a peptide specific sensitivity
If any adverse reaction occurs, stop using the product immediately and consult a healthcare professional for guidance.
Comedogenic Rating
Rating: 0/5. Oligopeptide-167 is water soluble, oil free and used at very low concentrations so it does not linger in pores or form a film that could trap sebum. Because it lacks fatty acids and waxes it is unlikely to block follicles. This makes it a suitable choice for people who are prone to acne or frequent breakouts. Only the surrounding formula, such as rich butters or occlusive silicones, would change a product’s overall pore-clogging potential so always check the full ingredient list.
Summary
Oligopeptide-167 is a lab crafted 22-amino-acid peptide that serves mainly as an antioxidant, neutralising free radicals generated by UV light, pollution and normal skin metabolism. By lessening oxidative stress it helps support a smoother brighter look and can complement sunscreen in a daily routine.
It is still a niche ingredient compared with headline actives like vitamin C or niacinamide, yet its stability and gentle profile are earning it spots in more serums and eye gels each year.
Overall safety data show a low risk of irritation or allergy and its non comedogenic nature suits all skin types. As with any new skincare ingredient it is smart to patch test a product first to confirm personal tolerance.