Ozonized Glycerin: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Ozonized Glycerin?

Ozonized Glycerin is glycerin that has been exposed to ozone, a form of oxygen, to create a blend of glycerol and oxygen-rich compounds called ozonides. The base glycerin usually comes from plant oils such as coconut or soybean, making the final ingredient largely plant derived. Ozone treatment was first explored more than a century ago for its cleansing power, and spa practitioners later used ozonated oils on the skin for a refreshed feel. As formulators looked for milder ways to tone and balance skin, they began applying the same idea to glycerin, which offers excellent skin compatibility.

Manufacturing is straightforward: highly purified glycerin is placed in a sealed reactor while a controlled stream of ozone gas bubbles through. Temperature, time and ozone concentration are carefully managed to reach a target level of ozonides without breaking down the glycerin backbone. The result is a clear, slightly thicker liquid with a faintly sharp scent that blends easily into water based or anhydrous products.

You will most often see Ozonized Glycerin in toners, balancing lotions, sheet masks, anti‐aging serums, after-shave splashes, deodorizing sprays and targeted treatments for oily or breakout-prone skin. It is prized for giving formulas a clean, tightened finish without the stinging associated with traditional alcohol heavy astringents.

Ozonized Glycerin’s Cosmetic Benefits/Uses

In skin care formulas the main value of Ozonized Glycerin is its role as a gentle astringent.

As an astringent it helps tighten the look of pores, remove excess surface oil and leave skin feeling smooth and refreshed. This action can give a matte finish, improve the appearance of fine lines caused by temporary swelling and prepare skin to better absorb follow-up products such as serums or moisturizers.

Who Can Use Ozonized Glycerin

Because it tones without harsh alcohol, Ozonized Glycerin works well for oily, combination and normal skin. Dry skin can also tolerate it when the final formula includes extra moisturizers, though very dehydrated or eczema-prone skin may find repeated use a little tight or itchy since the astringent action can pull water from the surface. Highly reactive or sensitized skin should proceed with care for the same reason.

Most suppliers make Ozonized Glycerin from vegetable glycerin and generate ozone on site, so no animal material or by-products are involved. This makes it a vegan and vegetarian friendly option as long as the finished product is cruelty free.

No specific warnings exist for pregnancy or breastfeeding. The ingredient does not enter deep circulation in any meaningful amount when used on intact skin. Even so this is not medical advice, and anyone who is pregnant or nursing should show the full product label to a health professional before starting a new routine.

Ozonized Glycerin does not increase photosensitivity, and it can be worn day or night without affecting sun protection needs.

Potential Side Effects/Adverse Reactions

Each person’s skin tolerance is different. The following points outline potential side effects that are possible yet uncommon when Ozonized Glycerin is used at appropriate levels in finished products.

  • Temporary stinging or warmth right after application
  • Dryness or tight feeling if the formula lacks added humectants
  • Redness or mild irritation on very sensitive skin
  • Allergic contact dermatitis in rare cases where a user is sensitive to glycerin derivatives
  • Increased irritation when layered with strong exfoliating acids or retinoids in the same routine

If any of these reactions occur stop using the product and consult a qualified healthcare provider or dermatologist.

Comedogenic Rating

Rating: 0 out of 5

Ozonized Glycerin is still based on glycerin, which is a small, water-loving molecule that easily dissolves in the skin’s surface moisture rather than collecting inside pores. The extra oxygen bonds formed during ozonation do not create heavier or oilier residues, so the ingredient remains unlikely to clog follicles. For these reasons it earns the lowest score possible on the comedogenic scale.

This makes Ozonized Glycerin generally suitable for people prone to acne or frequent breakouts.

As with any low-viscosity raw material, the final formula matters. If Ozonized Glycerin is blended into a very rich cream packed with waxes or butters, the product’s overall pore-clogging potential could rise even though the glycerin portion stays non-comedogenic.

Summary

Ozonized Glycerin acts mainly as a gentle astringent that helps tighten the look of pores, reduce surface oil and leave skin feeling smooth. It achieves these effects through the mild oxidative action of its ozonides combined with glycerin’s natural affinity for water, giving skin a refreshed matte finish without the sting of alcohol.

The ingredient is still something of a niche player compared with classic actives like niacinamide or hyaluronic acid, yet formulators who want a plant-derived toner component appreciate its versatility and mildness. You will see it most often in K-beauty style toners, refreshing mists and specialty serums aimed at balancing skin.

Overall safety is considered high at the low percentages typically used in cosmetics, with irritation or allergy remaining uncommon. Still, everyone’s skin is unique so it is wise to test a small area first any time you introduce a new product containing Ozonized Glycerin.

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