Palmitamine: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Palmitamine?

Palmitamine, also known by its chemical name hexadecylamine, is a fatty amine that comes from long-chain fatty acids found in palm oil or occasionally animal fats. Manufacturers obtain it by first splitting palm oil into its individual fatty acids, then reacting the C16 portion with ammonia and hydrogen in a high-pressure process that turns the acid into an amine. The result is a waxy, pale-yellow solid that melts easily into cosmetic formulas.

Fatty amines like palmitamine have been used since the 1950s to tame static in fabrics and soon found their way into personal care. Their ability to neutralize static charges made them ideal for hair products, especially as blow-drying and synthetic brushes gained popularity. Today you will most often see palmitamine in rinse-off and leave-in conditioners, anti-frizz creams, styling sprays, detangling mists, as well as some lotions and makeup where a smoother feel is desired.

Palmitamine’s Cosmetic Benefits/Uses

In formulas palmitamine serves one main role:

As an antistatic agent palmitamine helps reduce the build-up of electrical charges on hair strands. This keeps flyaways under control, makes combing easier and leaves hair looking smoother and better aligned. In creams and makeup it can also improve spreadability, giving the product a softer glide across the skin.

Who Can Use Palmitamine

Palmitamine is generally mild enough for all skin and hair types. Dry and frizz-prone hair in particular can benefit from its antistatic effect while oily or acne-prone skin is unlikely to be bothered because the ingredient is usually present at low levels and gets rinsed off in most formulations.

The raw material often comes from palm oil so it can be suitable for vegans and vegetarians when the manufacturer confirms a plant source. Some suppliers still process it from animal fats, so anyone following a strict vegan or vegetarian lifestyle should check with the brand to be sure.

No studies flag palmitamine as unsafe for pregnant or breastfeeding women when used in rinse-off or leave-on cosmetics at typical amounts. This is not medical advice and anyone who is pregnant or nursing should ask a healthcare professional before adding new products, just to be safe.

Palmitamine does not cause photosensitivity, meaning it will not make your skin or scalp more likely to burn in the sun. It also plays well with most other common beauty ingredients, so there are no special layering rules to follow.

Potential Side Effects/Adverse Reactions

Side effects from topical palmitamine can vary from person to person. The points below cover potential reactions, but most users will not experience them when the ingredient is properly formulated and used as directed.

  • Skin irritation – mild redness, itching or stinging on very sensitive skin
  • Contact allergy – rare cases of rash or swelling in individuals allergic to fatty amines
  • Eye irritation – burning or watering if the product accidentally gets into the eyes
  • Build-up on hair – a heavy or greasy feel if used in high-load leave-in formulas without regular washing

If you notice any of these reactions stop using the product and consult a healthcare professional for advice.

Comedogenic Rating

Rating: 1 / 5 — Palmitamine is classed as a very low-comedogenic ingredient because it is typically used at small percentages, has a cationic structure that rinses away easily and does not behave like greasy plant oils that can clog pores. Most products containing it are conditioners or sprays that either wash off or sit on the hair shaft rather than the skin surface, further lowering breakout risk. In short, it is generally considered safe for those prone to acne or congestion.

As with any ingredient, the full formula matters. Heavy leave-in creams packed with occlusive butters could still trigger breakouts even if palmitamine itself is low on the scale.

Summary

Palmitamine’s main job in cosmetics is to act as an antistatic agent that smooths flyaways, makes hair easier to comb and gives creams a softer glide. It does this by carrying a positive charge that neutralises the negative charges responsible for static electricity while its long fatty tail lays a light, conditioning film on hair or skin.

The ingredient is something of a quiet workhorse rather than a trending superstar. It shows up mostly in haircare where formulators need reliable, cost-effective static control but it rarely gets called out on front labels.

Overall safety is high when used at standard levels, with only rare reports of irritation or allergy. Still, everyone’s skin is different so it is wise to do a quick patch test whenever you try a new product that includes palmitamine.

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