Peg-40 Glyceryl Isostearate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Peg-40 Glyceryl Isostearate?

Peg-40 Glyceryl Isostearate is a plant-derived ingredient created by linking glycerin, isostearic acid and about forty units of ethylene oxide. Glycerin usually comes from vegetable oils, while isostearic acid is a branched fatty acid also sourced from plants such as soybean or rapeseed. When chemists join these pieces they get a mild, water-loving yet oil-friendly molecule that can sit at the border of oil and water.

Polyethylene glycol esters like this started appearing in skin care and hair care in the 1950s when formulators needed safer alternatives to harsh soaps. Over time Peg-40 Glyceryl Isostearate became popular because it pairs well with many other ingredients and keeps formulas stable even when stored for months.

The making process begins with the esterification of glycerin and isostearic acid to form glyceryl isostearate. That ester is then reacted with ethylene oxide so that about forty oxyethylene units are added, giving the final PEG-40 grade its good solubility in water.

You will most often spot Peg-40 Glyceryl Isostearate in facial cleansers, micellar waters, makeup removers, body washes, shampoos, lotions, light creams, sheet masks and baby care washes. Its gentle nature and versatility let brands use it in both rinse-off and leave-on products.

Peg-40 Glyceryl Isostearate’s Cosmetic Benefits/Uses

This multitasker brings two main benefits to personal care formulas

  • Cleansing: Its surfactant action loosens dirt, excess oil and makeup so they can be rinsed away without stripping the skin or hair
  • Emulsifying: It binds oil and water into a uniform blend which keeps creams and lotions from separating, makes clear cleansers stay clear and improves the feel of the final product

Who Can Use Peg-40 Glyceryl Isostearate

Peg-40 Glyceryl Isostearate is generally well tolerated by all skin types including dry, oily, combination and sensitive skin because it is mild and non-stripping. Those with extremely reactive or allergy-prone skin should still watch for any personal sensitivities to PEGs but most users find it gentle enough for daily use.

The ingredient is usually sourced from plant oils and contains no animal-derived components so it is broadly considered suitable for vegans and vegetarians. If a product carries a vegan claim it should confirm that every raw material, including this one, comes from non-animal sources.

Current safety data show no known risks for pregnant or breastfeeding women when Peg-40 Glyceryl Isostearate is applied to intact skin in cosmetic amounts. This is not medical advice and anyone who is pregnant or nursing should review any skincare routine with their physician to be on the safe side.

The molecule does not make skin more sensitive to sunlight and has no reported issues with photosensitivity. It is also odorless so it will not interfere with fragranced or fragrance-free formulations.

Potential Side Effects/Adverse Reactions

Reactions to topical Peg-40 Glyceryl Isostearate vary from person to person. The effects listed below are possible but not expected for the average user as long as the product is formulated correctly and used as directed.

  • Mild skin irritation such as redness or stinging in very sensitive individuals
  • Allergic contact dermatitis if someone is specifically allergic to PEG compounds
  • Eye irritation or temporary tearing if a cleanser containing it gets into the eyes
  • Dryness or tightness if used in high concentrations without enough moisturizers in the formula

If you experience any persistent discomfort while using a product with Peg-40 Glyceryl Isostearate stop using it and seek advice from a healthcare professional.

Comedogenic Rating

Rating: 1 out of 5. Peg-40 Glyceryl Isostearate is highly water soluble thanks to its long PEG chain so it rinses clean without leaving an oily film that could clog pores. The isostearic acid portion is branched which further reduces the chance of it packing tightly into pores. For most users it poses little risk of triggering blackheads or whiteheads.

Because of this low score the ingredient is generally considered suitable for acne-prone or breakout-prone skin. Only those who notice specific sensitivities to PEGs or fatty esters might need to avoid it.

Formulas that pair this surfactant with heavier occlusives or if used in very high amounts could alter the overall pore-clogging potential of the finished product so always look at the full ingredient list.

Summary

Peg-40 Glyceryl Isostearate acts mainly as a gentle cleanser and an emulsifier. Its PEG side makes it grab onto water while the fatty isostearate end anchors into oils so it lifts away dirt and makeup and keeps oil-water mixtures stable.

It shows up in a wide range of modern skincare and haircare though it is not the flashiest ingredient on the label. Brands like it because it plays well with actives fragrances and preservatives and it keeps formulas clear and consistent on the shelf.

Safety reviews rate it as low risk for irritation or sensitization when used at the levels found in cosmetics. Still individual skin can react differently so it is smart to patch test any new product containing Peg-40 Glyceryl Isostearate before adding it to your daily routine.

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