Peg-40 Glyceryl Triisostearate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Peg-40 Glyceryl Triisostearate?

Peg-40 Glyceryl Triisostearate is a plant- or vegetable-derived compound that marries glycerin, isostearic acid and ethylene oxide. Chemists start with natural fats rich in isostearic acid, react them with glycerin to form glyceryl triisostearate then add about 40 units of ethylene oxide. The end result is a waxy fluid that loves both oil and water, making it a useful helper in modern skin care.

The ingredient first appeared in cosmetic labs in the late twentieth century when formulators were looking for milder alternatives to harsh surfactants. Because Peg-based materials dissolve well in water, they quickly became favorites for creams and lotions that need a smooth, non-greasy feel.

Production involves three main steps: esterification of glycerin with isostearic acid, purification of the resulting triester and controlled ethoxylation to graft polyethylene glycol chains onto the molecule. The polyethylene glycol portion pulls in water while the fatty tails anchor into oils, giving the finished ingredient excellent balancing skills.

You will most often spot Peg-40 Glyceryl Triisostearate in facial cleansers, makeup removers, micellar waters, moisturizers, creamy body washes, sunscreens, hydrating masks and anti-aging serums. Its multitasking nature lets brands simplify formulas while still delivering a pleasant texture.

Peg-40 Glyceryl Triisostearate’s Cosmetic Benefits/Uses

This ingredient brings two key talents to a formula

  • Emollient: Softens and smooths skin by filling in tiny gaps on the surface so skin feels silky instead of rough
  • Emulsifying: Helps water and oil mix evenly which keeps creams stable, prevents separation in cleansing oils and creates that luxurious lotion texture consumers enjoy

Who Can Use Peg-40 Glyceryl Triisostearate

This ingredient is generally friendly to all skin types including dry, normal, combination, oily or sensitive skin because it is lightweight and non-greasy. People with very sensitive or compromised skin should still pay attention to how their skin feels, as with any new product, since individual tolerances differ.

Peg-40 Glyceryl Triisostearate is normally produced from plant oils and does not include any animal-derived materials, so it fits most vegan and vegetarian standards. Always check the full product label though, since other ingredients in the same formula could come from animal sources.

Current safety data show no known issues for women who are pregnant or breastfeeding when the ingredient is used as directed in rinse-off or leave-on products. This is not medical advice and anyone who is expecting or nursing should review new skincare items with a doctor first to stay on the safe side.

The ingredient does not make skin more sensitive to sunlight, so it will not increase the risk of sunburn. Standard daily sun protection is still wise for overall skin health.

Potential Side Effects/Adverse Reactions

Responses to topical Peg-40 Glyceryl Triisostearate vary from person to person. The effects listed below are uncommon and most users will not notice any problems when the ingredient is used in well-formulated products.

  • Mild skin irritation such as redness or itching
  • Stinging if applied to broken or freshly shaved skin
  • Allergic contact dermatitis in people who are sensitive to polyethylene glycol compounds
  • Temporary eye discomfort if the product accidentally gets into the eyes
  • Clogged pores or small breakouts in very acne-prone skin, especially if the overall formula is rich or occlusive

If you experience any of these reactions stop using the product and seek medical advice if symptoms persist or worsen.

Comedogenic Rating

Rating: 1 out of 5

Peg-40 Glyceryl Triisostearate carries a low risk of clogging pores because the large PEG portion keeps the molecule water-friendly and easily rinsed while the isostearic acid chains are branched, which makes them less likely to pack tightly inside pores. Most lab and user reports show little to no increase in blackheads or pimples when the ingredient is used at typical levels of 1-5% in finished products.

With a rating of 1 this ingredient is generally fine for people who break out easily, although the overall richness of the final formula still matters.

If used in very heavy balms or layered with other oily actives the risk could inch higher, so those with severe acne should still keep an eye on how their skin responds.

Summary

Peg-40 Glyceryl Triisostearate acts as a two-in-one helper: it softens skin as an emollient and keeps water and oil blended as an emulsifier. It does this by using its fatty isostearate tails to hug oils while its PEG side loves water, creating stable creams that feel smooth and light.

You will spot it in a fair share of cleansers, creams and makeup removers but it is not as famous as ingredients like glycerin or shea butter. Brands choose it when they need a gentle workhorse that is vegan-friendly and easy to formulate with.

Current research and decades of use show it is safe for most skin types with only rare irritation or allergy reports. As with any new skincare product a quick patch test is a smart move to make sure your skin stays happy.

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