Peg-50 Glyceryl Trioleate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Peg-50 Glyceryl Trioleate?

Peg-50 Glyceryl Trioleate is a plant-derived ingredient created by attaching about fifty units of ethylene oxide to glyceryl trioleate, the triglyceride form of oleic acid that naturally occurs in vegetable oils such as olive or sunflower oil. The resulting material looks like a pale, viscous liquid that dissolves easily in water and oil, making it a versatile helper in personal care formulas.

The idea of combining natural oils with polyethylene glycol (PEG) dates back to the mid-20th century when chemists were searching for gentler alternatives to harsh soaps. By turning an oily molecule into a partly water-loving one, they discovered a way to keep skin-friendly lipids in modern cleansers and creams without leaving a greasy film. Peg-50 Glyceryl Trioleate quickly found favor because its high PEG content improves rinse-off while the trioleate portion still feeds the skin a comforting dose of lipids.

Manufacturing starts with food-grade vegetable oil that is split into glycerin and oleic acid. The oleic acid is re-esterified with glycerin to rebuild glyceryl trioleate, which is then reacted with ethylene oxide under controlled heat and pressure. This step-wise process allows chemists to reach an average of fifty PEG units per molecule, a balance that gives both softness and solubility.

You will normally spot Peg-50 Glyceryl Trioleate in rinse-off cleansers, facial masks, creamy body washes, lightweight moisturizers, baby care lotions, makeup removers and leave-on conditioners. Formulators like it for products aimed at dry or sensitive skin because it helps formulas feel rich yet still wash away cleanly.

Peg-50 Glyceryl Trioleate’s Cosmetic Benefits/Uses

In skin and hair care, Peg-50 Glyceryl Trioleate plays more than one supportive role that improves how a product looks, feels and performs.

  • Emollient – Smooths and softens the surface of skin or hair by filling in microscopic gaps, which helps reduce roughness and boosts a silky after-feel
  • Emulsifying – Binds oil and water into a stable cream or lotion so the formula stays uniform, resists separation and spreads evenly during use

Who Can Use Peg-50 Glyceryl Trioleate

This gentle emollient suits most skin types, particularly dry, normal and sensitive complexions that crave extra cushioning. Its light texture rinses clean which keeps it comfortable even for combination or mildly oily skin, though those with very acne-prone skin may prefer humectants or lightweight esters instead.

The ingredient is synthesized from vegetable oils and petroleum-free ethylene oxide so it is suitable for vegetarians and vegans. No animal-derived starter materials are involved in standard production.

Pregnant or breastfeeding users can generally use products containing Peg-50 Glyceryl Trioleate because it stays on the outer layers of skin and has no known hormone activity. This is not medical advice and anyone expecting or nursing should review their routine with a healthcare professional to be safe.

Peg-50 Glyceryl Trioleate does not make skin more sensitive to sunlight and it has no known interactions with common UV filters. It is also mild enough for children and appears frequently in baby wash formulas.

Potential Side Effects/Adverse Reactions

Responses to topical Peg-50 Glyceryl Trioleate differ from person to person. The points below outline potential reactions that are possible yet uncommon when the ingredient is used at the typical levels found in finished cosmetics.

  • Contact irritation – transient redness stinging or warmth can occur on very reactive skin
  • Allergic dermatitis – rare sensitization may lead to itching hives or a rash
  • Eye irritation – may cause watering or burning if a cleanser or cream accidentally enters the eyes
  • Worsening breakouts – occlusive film can occasionally trap sebum on acne-prone areas leading to clogged pores
  • Increased penetration of other actives – its surfactant character can enhance the absorption of potent ingredients applied at the same time which could heighten their irritation potential

If any of these issues appear stop using the product and consult a qualified medical professional for guidance.

Comedogenic Rating

Rating: 2 / 5. While glyceryl trioleate on its own can block pores, the attachment of about fifty PEG units makes the molecule far more water dispersible and less likely to linger in follicular openings. The finished ingredient forms a light, rinse-friendly film so only a small portion stays on skin after cleansing or conditioning. At typical use levels it poses a low to moderate risk of clogging pores, though very blemish-prone users might still prefer oil-free textures.

In leave-on creams that sit on skin for many hours the chance of congestion rises slightly, especially if the formula also contains heavy butters or waxes. Concentration, overall product composition and how thoroughly the product is removed all influence the real-world comedogenicity of Peg-50 Glyceryl Trioleate.

Summary

Peg-50 Glyceryl Trioleate acts chiefly as an emollient and emulsifier. The oleic triglyceride portion slips into surface cracks to soften and smooth while the long PEG chain pulls the molecule toward water, letting it bridge oil and water so creams stay stable and rinse off cleanly. This dual nature is why formulators reach for it in gentle cleansers, baby washes and light lotions.

It is moderately popular: not as ubiquitous as classic fatty alcohols but valued in niche formulas that need a rich feel without greasy residue. Safety profiles and cosmetic regulations rate it as low risk with minimal irritation or toxicity data concerns, though extremely sensitive or acne-prone users may notice rare issues. As with any new skincare ingredient, perform a small patch test before regular use to make sure your skin agrees.

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