Peg/Ppg-28/21 Acetate Dimethicone: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Peg/Ppg-28/21 Acetate Dimethicone?

Peg/Ppg-28/21 Acetate Dimethicone is a silicone-based ingredient that carries both water-loving (PEG/PPG) and oil-loving (dimethicone) parts in the same molecule. The PEG/PPG numbers tell you how many units of polyethylene glycol and polypropylene glycol are linked to the silicone, while the acetate part comes from a mild acetic acid treatment that helps the whole blend spread easily on skin and hair. Chemists first explored these hybrid silicones in the late 1990s when brands wanted lighter silky textures that rinsed off without buildup. Today the ingredient is made by reacting a hydrogen-terminated silicone fluid with a blend of PEG/PPG allyl ethers, then capping the ends with acetate groups. This controlled reaction gives a clear liquid that is soluble in many surfactants and oils, making it handy for modern formulas.

You will find Peg/Ppg-28/21 Acetate Dimethicone in rinse-off and leave-on hair care such as shampoos, conditioners and styling creams. It also appears in facial cleansers, lightweight moisturizers, primers, masks and body washes where a soft touch and easy glide are desired.

Peg/Ppg-28/21 Acetate Dimethicone’s Cosmetic Benefits/Uses

This multi-tasking silicone improves how products feel and perform in several ways:

  • Hair Conditioning – coats strands in a thin flexible film that smooths cuticles, boosts shine and reduces frizz without weighing hair down
  • Skin Conditioning – leaves a breathable silky layer that softens rough patches, enhances slip and gives an instant smooth look on the surface of the skin
  • Cleansing – works with surfactants to lift away dirt and makeup while cushioning the skin or hair so the wash feels gentle not stripping

Who Can Use Peg/Ppg-28/21 Acetate Dimethicone

This ingredient is generally well tolerated by all skin types including dry, normal, combination and oily skin because it forms a breathable film that does not trap sweat or sebum. Very sensitive or highly reactive skin may still prefer to proceed with caution since any new synthetic polymer carries a small chance of irritation.

Peg/Ppg-28/21 Acetate Dimethicone is synthetic and produced without animal-derived raw materials so it suits both vegans and vegetarians.

No specific warnings exist for pregnancy or breastfeeding. The molecule is too large to penetrate deeply and is not known to interfere with hormones. Still this is not medical advice and anyone pregnant or nursing should have a doctor review any product they plan to use just to be safe.

The ingredient is non-photosensitizing and will not make skin more sensitive to sunlight. It is also odorless non-volatile and compatible with most other cosmetic actives so there are no special daytime or layering precautions.

Potential Side Effects/Adverse Reactions

Responses to topical Peg/Ppg-28/21 Acetate Dimethicone differ from person to person. The effects listed below are only potential issues and are unlikely for the average user when the product has been formulated correctly.

  • Mild skin irritation – very rare stinging or redness in people with compromised skin barriers
  • Allergic contact dermatitis – uncommon sensitization that can cause rash or itching
  • Follicular buildup on hair – overuse in leave-on hair products may leave a dull film that needs clarifying shampoo
  • Eye irritation – accidental contact can cause temporary tearing or blurred vision until rinsed out
  • Slippery surfaces – spillages of concentrated raw material can make bathroom floors slick increasing fall risk

If you experience any persistent discomfort or adverse change in skin or scalp condition stop using the product and seek advice from a qualified healthcare professional.

Comedogenic Rating

Rating: 1 / 5 – Peg/Ppg-28/21 Acetate Dimethicone sits on the surface in a thin breathable film and its water-dispersible PEG/PPG side makes it easier to rinse than heavier silicones. The molecule is too large to slip into pores and contains no fatty acids that typically trigger clogs, so the risk of blackheads is very low.

Suitable for acne-prone or breakout-prone skin in most cases.

Because it helps reduce friction, the ingredient can indirectly lessen rubbing-related pimples that some people experience from harsh cleansers or tight hairstyles.

Summary

Peg/Ppg-28/21 Acetate Dimethicone conditions hair, conditions skin and aids gentle cleansing. It does this by forming a lightweight silky film that smooths cuticles, softens rough skin and cushions surfactant action while still rinsing clean thanks to its PEG/PPG segments.

The ingredient is moderately popular, turning up in many mid to high-end shampoos, conditioners, face washes and primers where brands want the softness of silicone without heavy buildup.

Safety data show it is non-toxic, non-irritating for most users and unlikely to clog pores. As with any new cosmetic, give products containing this ingredient a quick patch test first to make sure your individual skin agrees with it.

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