Pentaclethra Macroloba Seed Oil Octyldodecyl Esters: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Pentaclethra Macroloba Seed Oil Octyldodecyl Esters?

Pentaclethra Macroloba Seed Oil Octyldodecyl Esters is a plant-derived ingredient that starts with the rich, butter-like oil pressed from the seeds of the pracaxi tree, a tall legume native to the Amazon. Chemists combine this seed oil with octyldodecanol, a silky fatty alcohol, through a process called transesterification. The result is a lighter, more stable ester that keeps many of the seed oil’s conditioning traits while gaining a smoother feel and longer shelf life.

The pracaxi tree has long been valued by local communities for its oil, used on hair and skin for softness and shine. As global interest in natural actives grew, formulators looked for ways to refine the raw oil so it could blend well with modern creams and serums. Partnering the oil with octyldodecanol produced an ester that resists oxidation, spreads easily and leaves no greasy residue, making it attractive to cosmetic brands seeking botanical alternatives to mineral oils and silicones.

Today you will find Pentaclethra Macroloba Seed Oil Octyldodecyl Esters in moisturizers, hair masks, leave-in conditioners, anti-aging creams, body butters and treatment oils for dry or damaged skin and hair. Its pleasant glide and conditioning profile also make it a popular choice for natural make-up, beard balms and after-sun products.

Pentaclethra Macroloba Seed Oil Octyldodecyl Esters’s Cosmetic Benefits/Uses

This versatile ester brings several performance benefits to personal care formulas

  • Hair conditioning: Forms a lightweight film that smooths the cuticle, boosts shine and helps reduce frizz which leaves strands softer and easier to comb
  • Skin conditioning: Supplies fatty acids that reinforce the skin barrier, improving softness, suppleness and overall comfort without a heavy feel
  • Emollient: Adds slip and a satiny finish to creams and oils, helping to lock in moisture and improve spreadability so products feel elegant during application

Who Can Use Pentaclethra Macroloba Seed Oil Octyldodecyl Esters

This silky ester is generally well tolerated by all skin types. Dry, normal and combination skins tend to appreciate its barrier-supporting fatty acids, while sensitive skin often enjoys its gentle non-stripping feel. Most oily or acne-prone users can also use it comfortably thanks to its light texture, yet anyone who knows they react easily to richer oils may want to monitor their skin for congestion just in case.

The ingredient comes entirely from plant sources: pracaxi seed oil and a vegetable-derived fatty alcohol. No animal derivatives or by-products are introduced during manufacturing so it is suitable for vegans and vegetarians.

No data suggest specific risks for pregnant or breastfeeding women when the ester is used topically in cosmetic amounts. Still, this is not medical advice and anyone who is expecting or nursing should have their healthcare provider review the full ingredient list of any product they plan to use to stay on the safe side.

Pentaclethra Macroloba Seed Oil Octyldodecyl Esters does not increase photosensitivity and has no known interactions with sunscreen filters or light-based treatments. It is also free of common fragrance allergens and essential-oil constituents, making it a practical option for users avoiding those sensitizers.

Potential Side Effects/Adverse Reactions

Responses to any cosmetic ingredient vary from person to person. The effects listed below are only potentials and are unlikely to represent the average experience when a well-formulated product is used as directed.

  • Mild skin irritation
  • Redness or stinging in very sensitive individuals
  • Allergic contact dermatitis in people with a specific seed or legume allergy
  • Occasional clogged pores or breakouts in users highly prone to comedones

If you notice itching swelling rash or any persistent discomfort stop using the product and consult a healthcare professional

Comedogenic Rating

Rating: 2 out of 5. The ester is derived from pracaxi seed oil, which contains a mix of saturated and unsaturated fatty acids, and from octyldodecanol, a mid-weight fatty alcohol that can occlude pores when used at high levels. Once these two are combined into an ester the finished molecule spreads more easily and absorbs faster than the raw materials, so it is less likely to sit on the skin long enough to clog pores. Most users with acne-prone skin tolerate it well, but those who break out easily from richer oils may still prefer to patch test first. The likelihood of congestion also depends on the overall formula: light emulsions and serums pose less risk than thick balms with a high oil phase.

Summary

Pentaclethra Macroloba Seed Oil Octyldodecyl Esters works as a hair conditioner, skin conditioner and emollient by forming a soft, breathable film that smooths hair cuticles, reinforces the skin barrier and leaves a silky after-feel without heaviness. It appears in a growing number of natural-leaning moisturizers, leave-ins and body oils, though it is still less common than plant butters like shea or mainstream esters such as cetearyl ethylhexanoate.

Current safety data show low irritation potential, no phototoxicity and minimal risk of sensitization outside of rare seed allergies, so it is considered safe for regular topical use. As with any new cosmetic ingredient it is smart to patch test a product before full application to make sure your individual skin agrees with it.

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