Perfluorononylethyl Carboxydecyl Hexacosyl Dimethicone: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Perfluorononylethyl Carboxydecyl Hexacosyl Dimethicone?

Perfluorononylethyl Carboxydecyl Hexacosyl Dimethicone is a specialty silicone made by joining traditional dimethicone with a short chain of fluorinated carbon atoms. The silicone part gives it a smooth feel while the fluorinated tail adds a light, water-repelling twist. Manufacturers usually start with standard silicone oils, then attach the fluorinated group through controlled chemical steps in a lab. The finished material is a clear fluid that spreads easily on skin and forms a breathable film.

The idea of blending silicones with fluorinated groups took off in the early 2000s when formulators looked for new ways to boost the staying power of skincare and makeup. By pairing two well-known chemistries they created an ingredient that feels silky yet resists sweat and humidity. Since then it has appeared in a growing number of beauty products.

You will most often spot Perfluorononylethyl Carboxydecyl Hexacosyl Dimethicone in lightweight moisturizers, anti-aging serums, primers, long-wear foundations, sheet masks and leave-on treatments that promise a soft finish without heaviness.

Perfluorononylethyl Carboxydecyl Hexacosyl Dimethicone’s Cosmetic Benefits/Uses

Its key role in skincare and makeup comes from its official function of skin conditioning.

As a skin-conditioning agent it coats the surface in a thin uniform layer that feels silky, reduces rough patches and helps other active ingredients spread evenly. The breathable film locks in moisture, boosts a product’s wear time and leaves skin looking smooth with a soft touch finish.

Who Can Use Perfluorononylethyl Carboxydecyl Hexacosyl Dimethicone

This lightweight silicone suits nearly all skin types. Dry and normal complexions appreciate the soft film that slows water loss while oily and combination skin benefit from its non-greasy slip that will not add shine. Even sensitive skin generally tolerates it well because the large silicone molecule stays on the surface rather than penetrating. Extremely acne-prone users may want to monitor how their skin responds since any film-forming ingredient can occasionally trap sebum, though this is uncommon.

The compound is fully synthetic, produced without animal materials so it is considered suitable for vegans and vegetarians. Cruelty status, however, rests on each brand’s overall testing policy.

No specific warnings exist for pregnancy or breastfeeding because the molecule is too big to reach the bloodstream in meaningful amounts. This is not medical advice and anyone who is pregnant or nursing should still clear all skincare choices with a qualified healthcare professional to be safe.

The ingredient does not cause photosensitivity and can be worn day or night. It layers well with sunscreens, retinoids, acids and other common actives without known incompatibilities.

Potential Side Effects/Adverse Reactions

Reactions to topical Perfluorononylethyl Carboxydecyl Hexacosyl Dimethicone vary from person to person. The points below list potential side effects yet most users will not experience them when the ingredient is used at normal levels in a properly formulated product.

  • Mild redness or stinging in very sensitive skin
  • Rare cases of allergic contact dermatitis resulting in itching or small bumps
  • Occlusive breakouts if the product is layered too heavily on pores already prone to congestion
  • Product pilling when combined with high levels of certain powders or waxes

If any of these issues occur stop using the product and consult a healthcare professional if symptoms persist or worsen.

Comedogenic Rating

Rating: 1 / 5

This low score reflects the ingredient’s large silicone structure which stays on the surface rather than sinking into pores. It creates a thin breathable film that is unlikely to block follicles though, like most film formers, it can trap excess oil if applied very heavily on skin already congested.

Generally considered safe for acne-prone users but those who break out easily may prefer lightweight formulas and moderate application.

The rating can vary slightly depending on the full formula: heavy waxes, butters or high pigment loads added to the same product may raise the overall clogging potential even if this silicone itself is mild.

Summary

Perfluorononylethyl Carboxydecyl Hexacosyl Dimethicone is a specialty silicone that conditions skin by laying down a silky water-resistant film. This film smooths rough spots, locks in moisture, improves spreadability of other actives and helps makeup last longer without feeling greasy.

While not as famous as plain dimethicone it is gaining steady traction in long-wear foundations, primers and lightweight serums thanks to its balanced mix of slip and humidity resistance.

Safety data points to very low irritation risk with only occasional reports of mild redness or clogged pores in sensitive users. As with any new cosmetic ingredient it is wise to patch test a small area first and watch how your skin responds before full use.

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