Piceatannol: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Piceatannol?

Piceatannol is a plant-derived compound that belongs to the stilbene family, the same group that includes the better-known resveratrol. It occurs naturally in passion fruit seeds, red grapes, blueberries and some types of peanuts. Chemically it is a small molecule with four hydroxyl groups, which makes it highly active against free radicals.

The compound was first isolated in the 1970s during studies on tropical fruits. As research on antioxidants grew, skincare scientists took note of piceatannol’s stability and stronger radical-scavenging ability compared with resveratrol. Over time it moved from laboratory curiosity to a valued cosmetic ingredient, especially in products focused on early signs of aging.

Commercially, piceatannol is made in two main ways. One is gentle solvent extraction from passion fruit seeds followed by purification. The other is a controlled conversion of resveratrol using food-grade catalysts. Both methods yield a purified powder that blends easily into water- or oil-based formulas.

You will most often see piceatannol in lightweight anti aging serums, revitalizing sheet masks, brightening eye creams, daily moisturizers and leave-on treatments meant to defend skin against pollution and other environmental stressors.

Piceatannol’s Cosmetic Benefits/Uses

In topical products piceatannol serves a single yet important role: antioxidant. By mopping up free radicals it helps shield skin from damage caused by UV light, urban pollution and normal metabolic processes. This protection can soften the look of fine lines, keep tone more even and support a smoother texture over time. Within the formula itself the antioxidant action also helps keep delicate oils and vitamins from breaking down, which means the product stays effective for longer.

Who Can Use Piceatannol

Piceatannol is gentle enough for most skin types, including dry, oily, combination and even sensitive skin, because it works as an antioxidant rather than an aggressive exfoliant or peel. Those with highly reactive or compromised skin should still introduce it gradually, as any new ingredient can trigger discomfort if the barrier is already inflamed.

The compound is either extracted from plant sources or produced through a plant based conversion of resveratrol, so it is suitable for vegans and vegetarians. No animal derived intermediates or animal testing are required for its manufacture in compliant supply chains.

Current data shows no known issues for pregnant or breastfeeding women when piceatannol is used topically in normal cosmetic concentrations. That said, this is not medical advice and anyone who is pregnant or nursing should run all skincare products past a doctor just to be on the safe side.

Piceatannol is not known to cause photosensitivity, so it does not increase the chance of sunburn. Daily sunscreen is still recommended for overall skin health.

Potential Side Effects/Adverse Reactions

Responses to topical piceatannol can vary from person to person. The following list covers potential side effects yet these are uncommon when the ingredient is formulated correctly in a finished product.

  • Mild redness or warmth shortly after application
  • Transient itching or tingling in very sensitive skin
  • Contact dermatitis in individuals allergic to stilbene related compounds
  • Possible interaction with highly acidic or strong exfoliating products, which may heighten overall skin sensitivity

If any persistent or severe reaction occurs stop using the product immediately and seek guidance from a healthcare professional.

Comedogenic Rating

Rating: 0 / 5

Piceatannol is a very small molecule that stays mainly in the watery part of a formula and does not leave an oily film on skin. It has no known tendency to clog pores because it is not an oil, butter or wax and it is used at low concentrations. For these reasons it earns a solid zero on the comedogenic scale.

That makes it suitable for people who are prone to acne or frequent breakouts.

Formulators sometimes pair piceatannol with lightweight humectants and quick-drying emulsions, which keeps finished products friendly to oily or congested skin types.

Summary

Piceatannol works mainly as a high-strength antioxidant, neutralising free radicals before they can chip away at collagen or trigger uneven tone. By cutting down this daily oxidative stress it helps skin look smoother and stay resilient while also protecting other delicate ingredients inside the bottle.

Although it is not as famous as vitamin C or resveratrol, interest in piceatannol is rising among indie brands looking for fresh yet proven antioxidants. Its plant origin, stability and gentle profile make it an attractive addition to modern anti aging or pollution defense lines.

Current research and cosmetic use data show piceatannol to be safe for topical use across most skin types with very low risk of irritation. As with any new skincare ingredient it is smart to do a small patch test before fully adding it to your routine just to be sure your skin agrees.

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