What Is Pichia Sr-Cow Polypeptide-2 Ferment Lysate Filtrate?
Pichia Sr-Cow Polypeptide-2 Ferment Lysate Filtrate comes from Pichia pastoris, a type of yeast often used in biotechnology. Scientists tweak this yeast so it can produce sr-Cow Polypeptide-2, a small chain of amino acids. During production the yeast grows in large stainless-steel tanks filled with a nutrient-rich broth. Once the culture reaches the right stage the cells are broken apart, releasing their contents. The mixture is then filtered to remove cell debris, leaving a clear liquid known as the lysate filtrate. This liquid holds the peptide along with vitamins, sugars and minerals naturally present in yeast.
Yeast-derived ferments entered skin care in the late 1970s when brands noticed that workers in sake breweries had unusually smooth hands. Since then labs have explored different yeast strains for their antioxidant and skin-friendly properties. Pichia pastoris became popular because it grows fast, is easy to control and can be programmed to make specific peptides like sr-Cow Polypeptide-2.
Today Pichia Sr-Cow Polypeptide-2 Ferment Lysate Filtrate appears in lightweight serums, anti-aging creams, sheet masks, eye treatments, after-sun gels and daily moisturizers where brands want a biotech-driven boost without heavy oils.
Pichia Sr-Cow Polypeptide-2 Ferment Lysate Filtrate’s Cosmetic Benefits/Uses
This ferment brings two key actions to a formula
- Antioxidant – helps neutralize free radicals created by UV rays pollution and stress which can dull the skin and speed up the look of aging. By mopping up these unstable molecules the ingredient supports a brighter more even complexion and may help protect the integrity of collagen and elastin
- Skin conditioning – supplies amino acids and sugars that bind water to the skin surface improving softness and smoothness. Regular use can leave skin feeling hydrated cushioned and more resilient
Who Can Use Pichia Sr-Cow Polypeptide-2 Ferment Lysate Filtrate
This ferment suits most skin types including dry, normal, combination and oily because it is water-light and non-greasy. Sensitive skin usually tolerates it well thanks to its gentle antioxidant profile, though anyone with a known yeast allergy should be cautious as the ingredient is derived from Pichia pastoris.
The material is produced entirely in a lab using yeast and a synthesized cow-derived peptide sequence, without any animal tissue, milk or by-products. That makes it acceptable for vegans and vegetarians, though extremely strict lifestyles may prefer to avoid it due to the bovine gene origin.
No research links this ferment to hormonal disruption, so pregnant or breastfeeding women can generally use it. This is not medical advice and anyone expecting or nursing should run new products past a doctor first to be safe.
The filtrate does not increase sun sensitivity, so it can be applied morning or night. As with any skincare active it layers well with sunscreen and other antioxidants like vitamin C or niacinamide.
Potential Side Effects/Adverse Reactions
Responses to topical Pichia Sr-Cow Polypeptide-2 Ferment Lysate Filtrate vary from person to person. The following is a list of potential side effects that are unlikely for most users when the ingredient is correctly formulated and used as directed.
- Temporary redness or mild stinging
- Itchiness or a warm sensation
- Contact dermatitis in individuals sensitive to yeast extracts
- Localized swelling or hives indicating an allergic reaction
- Possible flare of fungal acne in those already prone to Malassezia issues
If any of these reactions occur stop using the product and consult a healthcare professional or dermatologist.
Comedogenic Rating
Rating: 0/5
Pichia Sr-Cow Polypeptide-2 Ferment Lysate Filtrate is water based, oil free and low in residue so it does not clog pores or sit heavily on the skin. The molecules it contains are mostly small peptides, sugars and minerals that rinse or absorb cleanly without leaving a waxy film. Because it lacks fatty acids or thick emollients it earns the lowest possible comedogenic score.
Suitable for acne-prone or breakout-prone skin.
Formulators often pair this ferment with lightweight hydrators so finished products usually stay non comedogenic, though the full formula still decides the final pore-clogging risk.
Summary
Pichia Sr-Cow Polypeptide-2 Ferment Lysate Filtrate works as an antioxidant and skin-conditioning agent. Its yeast-derived peptides help neutralize everyday free radicals while the natural amino acids and sugars draw moisture to the surface leaving skin softer brighter and more resilient.
The ingredient shows up in a modest number of innovative serums masks and creams, especially from brands that highlight biotech actives. It is not yet mainstream like hyaluronic acid but is gaining traction as formulators look for gentle lab grown alternatives to plant extracts.
Overall safety data are reassuring with low irritation and no known systemic concerns. As with any new skincare active do a quick patch test when trying a product that includes this ferment to make sure your skin agrees with it.