What Is Pichia/Glycerin/Methyl Alcohol/Ammonium Hydroxide Ferment Extract Filtrate?
Pichia/Glycerin/Methyl Alcohol/Ammonium Hydroxide Ferment Extract Filtrate is a liquid ingredient obtained by fermenting a blend of glycerin, methyl alcohol and ammonium hydroxide with the yeast Pichia. After fermentation the mixture is filtered to remove solid matter, leaving a clear nutrient rich filtrate. The resulting liquid contains a mix of amino acids, peptides, vitamins and sugars produced by the yeast along with humectant glycerin, giving it useful skin friendly properties.
Yeast derived ingredients have been part of skin care since the 1970s when Japanese researchers noticed workers in sake breweries had unusually smooth youthful hands. Since then different species of yeast, including Pichia, have been explored for their ability to create bioactive compounds during fermentation. Pichia/Glycerin/Methyl Alcohol/Ammonium Hydroxide Ferment Extract Filtrate grew out of that trend as formulators looked for new ways to combine fermentation science with familiar moisturizers like glycerin.
The production process is similar to brewing. A sterile solution containing glycerin, a small amount of methyl alcohol and ammonium hydroxide is inoculated with Pichia cells and kept at controlled temperature and pH so the yeast can metabolize the mixture. Over several days the yeast secretes skin conditioning molecules. The broth is then filtered, sometimes further refined, and preserved for use in cosmetics.
You will most often find this filtrate in hydrating serums, anti aging creams, sheet masks, soothing lotions, essence type products and post exfoliation treatments that aim to replenish moisture and support the skin barrier.
Pichia/Glycerin/Methyl Alcohol/Ammonium Hydroxide Ferment Extract Filtrate’s Cosmetic Benefits/Uses
This ingredient is valued mainly for one clear role in skin care. As a skin conditioning agent it helps keep the outer layer of skin soft, smooth and well hydrated. The naturally occurring amino acids and sugars act as humectants that draw water to the surface, while fermented peptides can support a healthier looking skin barrier. Formulators add the filtrate to give products a light, refreshing feel and to boost overall moisturization without heaviness.
Who Can Use Pichia/Glycerin/Methyl Alcohol/Ammonium Hydroxide Ferment Extract Filtrate
This ferment filtrate is gentle enough for most skin types including dry, normal, combination and sensitive skin thanks to its lightweight humectant profile. Oily or acne prone users can also benefit because the ingredient is water based and non greasy though those highly reactive to yeast derived actives may wish to proceed slowly.
The material contains no animal derived components and the fermentation process relies on yeast, so it is usually considered suitable for both vegans and vegetarians. Always check the full product label for any added non vegan ingredients.
Based on current safety data the filtrate is not known to pose specific risks for women who are pregnant or breastfeeding when used topically in cosmetic amounts. This is not medical advice and anyone who is pregnant or nursing should run any skincare product they plan to use past a qualified doctor just to be on the safe side.
The ingredient does not increase photosensitivity so there is no special need to avoid sunlight beyond the usual daily SPF recommendation.
Potential Side Effects/Adverse Reactions
Side effects and reactions to topical Pichia/Glycerin/Methyl Alcohol/Ammonium Hydroxide Ferment Extract Filtrate can vary from person to person. The points below list potential issues but most users will not experience them when the ingredient is formulated and used correctly.
- Mild redness or stinging on very sensitive skin
- Temporary itching or tingling when applied to freshly exfoliated or compromised skin
- Allergic response to yeast proteins leading to rash or swelling
- Contact dermatitis triggered by individual sensitivity to fermentation by products
- Rare cross reaction with other strong actives in the same routine that can amplify irritation
If any adverse reaction occurs discontinue use immediately and seek advice from a healthcare professional or dermatologist.
Comedogenic Rating
Rating: 0 / 5
Pichia/Glycerin/Methyl Alcohol/Ammonium Hydroxide Ferment Extract Filtrate is a water based ingredient with small molecule humectants and low residue levels of the original ferment medium. It leaves no oily film, does not contain fatty acids or waxes that can clog pores and is readily rinsed from the skin. For these reasons it earns a solid 0, indicating virtually no risk of blocking follicles.
Suitable for acne-prone and breakout-prone skin.
Formulations that pair the filtrate with heavy occlusives, rich butters or high levels of silicones may raise the overall comedogenic potential of a finished product, so always judge the formula as a whole.
Summary
Pichia/Glycerin/Methyl Alcohol/Ammonium Hydroxide Ferment Extract Filtrate is a skin conditioning ferment that hydrates by drawing moisture to the surface and supplies amino acids and peptides that help keep the barrier smooth and supple. Thanks to its lightweight water like texture it boosts moisture without greasiness, making it easy to slot into serums, essences and creams.
The ingredient sits in the niche category of fermentation actives: not as famous as classic hydrators like hyaluronic acid yet steadily gaining interest among brands that lean on K-beauty or J-beauty trends.
Current data show it to be low risk for topical use with very rare reports of irritation or allergy. As with any new skincare addition it is smart to perform a quick patch test before full application just to be safe.