Pig Platelet-Rich Plasma: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Pig Platelet-Rich Plasma?

Pig Platelet-Rich Plasma is a skincare ingredient created by concentrating the platelets found in pig blood. These platelets are tiny cell fragments rich in growth factors and proteins that naturally help repair tissue and maintain moisture. Interest in animal-derived platelet products began in medical wound care, and formulators soon explored their potential in beauty products for improved hydration and skin resilience. To make Pig Platelet-Rich Plasma, fresh pig blood is drawn under strict veterinary and hygienic controls, then spun in a centrifuge to separate red cells from a clear plasma layer packed with platelets. The resulting fluid is filtered, stabilized and blended into cosmetic bases. You will mainly find it in sheet masks, restorative serums, intensive moisturizers, anti-aging creams and post-treatment soothing gels.

Pig Platelet-Rich Plasma’s Cosmetic Benefits/Uses

Below are the key ways this ingredient can improve a formulation and the skin on which it is applied.

  • Humectant: The plasma holds water-binding proteins that pull moisture from the environment into the upper skin layers, helping keep the complexion plump and comfortable.
  • Skin Protecting: Its growth factors and antioxidants form a lightweight shield that supports the skin’s natural barrier, reducing the impact of daily stress like dry air and pollution while encouraging a smoother surface.

Who Can Use Pig Platelet-Rich Plasma

Pig Platelet-Rich Plasma is generally well tolerated by most skin types including dry, normal, oily and combination skin because its main roles are adding moisture and supporting the skin barrier. Very sensitive or highly reactive skin may still prefer a simpler formula since any animal protein can rarely trigger redness or itching in those who are prone.

Because the ingredient comes directly from pigs it is not suitable for vegans or vegetarians who avoid animal-derived products. People who keep a plant-based lifestyle will want to pick a different humectant such as glycerin or hyaluronic acid.

Current research does not point to any specific risks for pregnant or breastfeeding women when Pig Platelet-Rich Plasma is used topically in a properly made cosmetic. Still this is not medical advice and anyone who is expecting or nursing should show the product to a doctor first to be safe.

The ingredient does not make skin more sensitive to sunlight so routine use does not require extra sun precautions beyond a daily broad-spectrum sunscreen.

Potential Side Effects/Adverse Reactions

Responses to topical Pig Platelet-Rich Plasma differ from person to person. The points below outline potential but uncommon effects assuming the product is manufactured and stored correctly and used as directed.

  • Allergic reaction – itching, hives or swelling in users who are sensitive to animal proteins
  • Skin irritation – temporary redness or stinging, usually in very sensitive or compromised skin
  • Breakouts – clogged pores in acne-prone skin if the finished formula is rich or occlusive
  • Odor changes – a slight metallic or meaty smell that some users find unpleasant even when the product is fresh
  • Contamination risk – infection or folliculitis if the plasma is not properly sterilized before being added to the cosmetic base

If you notice any of the above reactions stop using the product and seek advice from a healthcare professional.

Comedogenic Rating

Rating: 1/5

Pig Platelet-Rich Plasma is mainly made of water soluble proteins and growth factors with very little residual fat so it has a low tendency to block pores. The rating sits at 1 rather than 0 because trace lipids or stabilizers that come with the plasma could, in rare cases, contribute to mild congestion.

Overall it is considered suitable for people who are prone to acne or breakouts, provided the finished product is light and non-occlusive.

Keep in mind that the final formula matters; heavy creams or balms using this ingredient may still cause issues even though the plasma itself is nearly non-comedogenic.

Summary

Pig Platelet-Rich Plasma works as a humectant by drawing water into the upper skin layers, keeping the surface hydrated and supple. It also serves a skin protecting role because its growth factors and antioxidants reinforce the barrier and help the skin cope with daily stress.

The ingredient has a niche following in beauty circles that enjoy novel animal derived actives, but its popularity is limited by ethical concerns, sourcing challenges and the availability of plant based alternatives.

When sourced and processed correctly Pig Platelet-Rich Plasma is generally safe for topical use with low irritation potential. As with any new skincare addition it is smart to perform a small patch test first to check for personal sensitivity.

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