Placental Lipids: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Placental Lipids?

Placental lipids are the oily components extracted from the placenta, the temporary organ that supports a developing fetus during pregnancy. These lipids include fatty acids, phospholipids, sphingolipids and cholesterol, all of which are naturally present in human skin. Traditionally the cosmetic industry has relied on ovine or porcine placentas collected after birth from inspected sources, though some brands now turn to bio-identical or plant-mimicking versions to address ethical concerns. Interest in placenta-based beauty dates back to the mid-20th century when salons in Europe and Japan promoted placental extracts for their rejuvenating feel. To obtain placental lipids, the tissue is cleaned, enzymatically or mechanically broken down, then subjected to food-grade solvents that separate the lipid fraction. The raw extract is filtered, deodorised and standardised into an odour-controlled, cream-coloured paste or liquid suitable for skincare. Formulators add placental lipids to moisturisers, anti-aging creams, nourishing face masks, rich night balms, eye treatments and even conditioning hair serums where a cushiony skin feel or soft finish is desired.

Placental Lipids’s Cosmetic Benefits/Uses

In topical products placental lipids serve one primary role.

As an emollient they fill in microscopic cracks on the skin surface, creating a smooth even feel that reduces roughness, boosts suppleness and helps limit water loss. This leaves skin looking softer and more radiant while enhancing the spreadability and luxury texture of the final formula.

Who Can Use Placental Lipids

Because placental lipids closely resemble the skin’s own fats they are generally well tolerated by most skin types, especially normal dry mature or sensitised complexions craving extra nourishment. The ingredient can feel heavy on very oily acne-prone skin so those users may prefer lighter alternatives or formulas where the concentration of placental lipids is low.

Traditional placental lipids are sourced from animal tissue, making them unsuitable for vegans or strict vegetarians. Some brands offer bio-identical or plant-mimicking versions advertised as “placental-like lipids” yet anyone following a plant-based lifestyle should double-check sourcing with the manufacturer.

Current research shows no specific safety concerns for pregnant or breastfeeding women when the ingredient is used topically, but data are limited. This is not medical advice and expectant or nursing mothers should run any skincare product past a qualified healthcare professional before use.

Placental lipids are not known to cause photosensitivity and do not require daytime users to take special sun protection measures beyond routine sunscreen.

Potential Side Effects/Adverse Reactions

Reactions to topical placental lipids vary from person to person. The points below outline potential though uncommon side effects when the ingredient is included in a properly formulated cosmetic product. Most users will not experience these issues.

  • Allergic contact dermatitis presenting as redness itching or small bumps
  • Breakouts or congestion in individuals prone to acne due to the lipid-rich texture
  • Skin irritation from residual proteins or processing solvents if purification is inadequate
  • Unpleasant odor or product spoilage if the lipids oxidise over time

If any adverse reaction develops discontinue use immediately and seek guidance from a healthcare professional or dermatologist.

Comedogenic Rating

Rating: 3 out of 5. Placental lipids are rich in fatty acids and cholesterol that can soften skin, but this same richness can sit heavily on pores, especially when used in high concentrations or layered with other occlusive ingredients. While their molecular profile is similar to the skin’s own fats and they do absorb better than some heavier plant butters, they still have a moderate likelihood of clogging pores in oil-rich or breakout-prone complexions. Acne-prone users should therefore approach with caution and look for low-percentage formulas or lighter textures. Formulation quality, antioxidants and proper storage also influence whether the lipids oxidise and become more pore-clogging over time.

Summary

Placental lipids act primarily as an emollient, smoothing the skin surface, filling micro cracks and helping to slow water loss so skin feels soft, supple and comfortable. They achieve this thanks to their mix of fatty acids, phospholipids, sphingolipids and cholesterol which mirror the lipids found naturally in our own skin barrier.

Although placenta-based beauty had its heyday decades ago it now occupies a niche spot in modern skincare, appearing mostly in heritage European creams, select K-beauty formulas and a handful of boutique serums. Ethical sourcing questions and the rise of plant alternatives have limited its mainstream popularity yet fans still praise its cushiony feel.

Topically applied placental lipids are considered safe for most skin types with few documented risks when properly purified, though animal sourcing can be a concern for vegans. As with any new skincare ingredient do a simple patch test before full use to make sure your skin agrees with it.

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