Poloxamer 105: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Poloxamer 105?

Poloxamer 105 is a synthetic, non-ionic surfactant made by linking blocks of propylene oxide and ethylene oxide in a specific pattern. The result is a wax-like solid that dissolves easily in water and oil, letting it interact with both. First introduced in the 1950s under the trade name Pluronic, this family of ingredients found its way into cosmetic labs in the early 1970s when formulators noticed how gently these molecules lift away dirt and oil. Manufacturing starts with a small propylene glycol core; propylene oxide is added to build the central hydrophobic block, then ethylene oxide is added to create two hydrophilic end blocks. By adjusting the length of each block, chemists fine-tune the balance between oil-loving and water-loving parts, giving Poloxamer 105 its mild cleansing power. Today you will spot it in facial cleansers, micellar waters, makeup removers, shower gels, shampoos, sheet masks, lightweight moisturizers and after-sun gels where a gentle yet effective surfactant or stabilizer is needed.

Poloxamer 105’s Cosmetic Benefits/Uses

Formulators choose Poloxamer 105 for two key reasons

  • Cleansing: Its amphiphilic structure surrounds oil, sunscreen residue and makeup so they can be rinsed off with water. Because it is non-ionic it cleans without stripping, making it suitable for sensitive skin and daily use.
  • Emulsifying: It stabilizes blends of oil and water, preventing separation and helping products stay smooth and uniform. This keeps lotions, gels and micellar waters looking clear and feeling silky throughout their shelf life.

Who Can Use Poloxamer 105

Thanks to its gentle, non-ionic nature Poloxamer 105 suits almost every skin type, from oily and combination to dry and sensitive. People with extremely dry or compromised skin should still watch for any extra tightness because all surfactants can remove some natural oils. The ingredient is made entirely in the lab without animal by-products so it is generally considered appropriate for vegans and vegetarians, though cruelty-free status depends on the brand’s overall testing policy. Current safety data show no special concerns for women who are pregnant or breastfeeding; still, this is not medical advice and anyone expecting or nursing should run new skincare past a doctor to be safe. Poloxamer 105 does not make skin more prone to sunburn and it can even be found in some contact lens solutions, underscoring its mild profile.

Potential Side Effects/Adverse Reactions

Reactions to topical Poloxamer 105 differ from person to person. The points below list potential side effects but most users will not encounter them when the ingredient is properly formulated.

  • Mild skin irritation such as redness stinging or a warm feeling right after use
  • Dryness or tightness if the product is left on the skin too long or used very frequently
  • Allergic contact dermatitis in rare cases for individuals who develop a specific sensitivity
  • Transient eye irritation if the cleanser accidentally gets into the eyes

If any of these issues arise stop using the product and consult a healthcare professional or dermatologist for guidance.

Comedogenic Rating

Rating: 0 / 5. Poloxamer 105 is highly water soluble and does not leave a greasy film on the skin. Its molecules rinse away cleanly rather than lingering inside pores, so it does not create the kind of plug that can lead to blackheads or pimples. For these reasons it is considered safe for people who are prone to acne or frequent breakouts. Because it is often used at low concentrations and typically in rinse-off formulas, the likelihood of clogging pores is extremely low.

Summary

Poloxamer 105 works as a mild cleanser and emulsifier, lifting oil and debris while keeping water-and-oil mixes stable. It does this through its unique block-copolymer structure, which has both water-loving and oil-loving segments that surround dirt so it can be washed away without harshness.

The ingredient is not a household name like hyaluronic acid or glycerin but it enjoys steady use behind the scenes in micellar waters, gentle face washes and even contact lens solutions because formulators trust its reliability and skin friendliness.

Current research and decades of practical use show that Poloxamer 105 is low risk for irritation or pore clogging when formulated correctly. As with any new skincare product it is wise to perform a simple patch test first to make sure your skin agrees with the full formula.

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