Poloxamer 182: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Poloxamer 182?

Poloxamer 182 is a man-made ingredient that belongs to a family of block copolymers built from polyethylene glycol and polypropylene glycol. These two parts are repeated in a set pattern, giving the material both water-loving and oil-loving sections which make it very useful in skin and hair care.

The compound is created through controlled polymerization. First, propylene oxide is turned into a polypropylene glycol core. Ethylene oxide is then added to each end of that core to form the final block structure. The numbers in its name point to the average length of each block. Because the process takes place in closed reactors and uses food-grade raw materials, the final product is high in purity and very stable.

Poloxamers began to appear in personal care during the 1970s when formulators were searching for surfactants that were mild, easy to rinse and able to work in a wide pH range. Over the years they have gained a solid place in face washes, baby shampoos and sensitive skin products.

You will most often spot Poloxamer 182 in liquid or gel cleansers, micellar waters, makeup removers, exfoliating pads, sheet mask serums, body washes and even some lightweight moisturizers where it helps keep oil and water mixed.

Poloxamer 182’s Cosmetic Benefits/Uses

Here is how Poloxamer 182 helps a formula perform at its best:

  • Cleansing: Its dual-nature structure surrounds dirt and excess oil so they can be lifted from the skin or hair and rinsed away with water. Because it is nonionic it tends to be gentle and less likely to strip the skin barrier.
  • Emulsifying: It stabilizes blends that contain both oil and water, preventing them from separating while sitting on the shelf or during use. This keeps creams, gels and serums smooth and consistent so every application feels the same.

Who Can Use Poloxamer 182

Poloxamer 182 is generally considered suitable for all skin types, including dry, oily, combination and sensitive skin, because its nonionic nature makes it mild and unlikely to disturb the skin’s natural barrier. People with very compromised or highly reactive skin should still watch how their skin responds, simply because any new ingredient can behave differently on a damaged barrier.

The ingredient is synthesized entirely from petrochemical feedstocks and contains no animal-derived components, so products using Poloxamer 182 are typically vegan and vegetarian friendly. That said, always look at the complete formula to be sure no other animal ingredients are present.

Current safety data show no specific risks for women who are pregnant or breastfeeding when Poloxamer 182 is applied topically. It is widely used in baby products and medical rinses, which supports its gentle reputation. This is not medical advice and anyone who is expecting or nursing should run their whole skincare lineup past a qualified healthcare provider just to be safe.

Poloxamer 182 does not make skin more sensitive to sunlight, so there is no added concern about photosensitivity when using it. It is also odorless and has no known interaction with common skincare actives like vitamin C, niacinamide or retinoids, which makes it easy to slot into almost any routine.

Potential Side Effects/Adverse Reactions

Side effects from topical Poloxamer 182 can vary from one person to another. The points below are only potential reactions and are not the norm. When used at the levels typically found in cosmetics most users will not notice any negative effect.

  • Mild skin irritation: A small number of people may experience temporary redness or stinging, usually if the product also contains other strong actives
  • Allergic contact dermatitis: Extremely rare but possible if someone is specifically sensitized to the polymer or a trace impurity
  • Eye irritation: High concentrations splashed directly into the eyes can cause watering or discomfort though rinse-off products greatly reduce this risk

If irritation or any unexpected reaction occurs stop using the product and seek advice from a medical professional if symptoms persist.

Comedogenic Rating

Rating: 0/5 (non-comedogenic)

Poloxamer 182 is fully water soluble and does not leave an oily film on the skin, so it is highly unlikely to block pores or trap sebum. Its cleansing action actually helps lift away residue that could otherwise contribute to breakouts.

Because of this low risk of clogging, Poloxamer 182 is generally considered safe for acne-prone or breakout-prone skin.

The ingredient also rinses off easily, which further limits the chance of it lingering on the skin and causing congestion.

Summary

Poloxamer 182 acts mainly as a cleanser and emulsifier. Its block copolymer structure has one part that loves water and another that loves oil, letting it surround dirt and makeup then suspend them in water so they wash away without harsh rubbing. The same structure keeps oil and water mixed in lotions, gels and micellar waters so the texture stays smooth from the first pump to the last.

While not as famous as hyaluronic acid or glycerin, Poloxamer 182 has a solid place in many gentle face washes, baby shampoos and makeup removers because it is mild, versatile and easy to formulate with.

Current data show it is very safe for topical use, with a low risk of irritation or allergy and practically no comedogenic potential. As with any new product, a quick patch test is still a smart step before adding it to your daily routine.

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