Polyglyceryl-10 Dodecacaprylate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Polyglyceryl-10 Dodecacaprylate?

Polyglyceryl-10 Dodecacaprylate is a plant-derived ingredient made by joining ten glycerin units with twelve molecules of caprylic acid, which comes from coconut or palm oil. This reaction creates a mild ester that carries the balancing traits of both water-loving glycerin and oil-loving fatty acids. Cosmetic chemists began turning to this material in the early 2000s when brands looked for gentler alternatives to traditional PEG-based emulsifiers. To produce it, manufacturers first create polyglyceryl-10 from renewable glycerin, then slowly react it with purified caprylic acid under heat and vacuum until the lightweight ester forms. The final material is biodegradable, free of ethylene oxide and well suited for modern “clean” formulations.

You will most often spot Polyglyceryl-10 Dodecacaprylate in moisturizers, lotions, face masks, sunscreens, baby care, sensitive skin products and lightweight serums where a soft non-greasy feel is important.

Polyglyceryl-10 Dodecacaprylate’s Cosmetic Benefits/Uses

Its key job in a formula is to act as an emulsifying agent. By sitting at the boundary between oil and water it helps the two phases stay blended, so the product stays smooth from the first pump to the last drop. A stable emulsion gives creams and lotions a pleasing texture, spreads evenly on the skin and keeps active ingredients distributed for consistent performance.

Who Can Use Polyglyceryl-10 Dodecacaprylate

This emulsifier is gentle enough for every skin type. Dry and mature skin appreciate the soft feel it brings, oily or acne-prone skin like that it is lightweight and does not add a greasy film, and sensitive skin benefits from its mild nature and lack of common irritants.

The ingredient is made from plant glycerin and coconut or palm sourced caprylic acid, so it is suitable for vegans and vegetarians. No animal-derived raw materials or by-products are used during production.

Current research shows no issues for women who are pregnant or breastfeeding because the molecule sits on the skin’s surface and is not expected to reach the bloodstream. Still, this is not medical advice and anyone who is pregnant or nursing should run all skincare choices past a healthcare professional just to be safe.

Polyglyceryl-10 Dodecacaprylate does not make skin more sensitive to sunlight and can be worn morning or night without extra sun precautions beyond a normal SPF routine.

Potential Side Effects/Adverse Reactions

Reactions to the topical use of Polyglyceryl-10 Dodecacaprylate can vary from person to person. The effects listed below are only potential outcomes and are unlikely to occur for the average user when the ingredient is formulated correctly.

  • Mild skin irritation such as temporary redness or itching
  • Rare allergic contact dermatitis in people sensitive to glycerin derivatives or coconut fractions
  • Eye stinging if a product is rubbed directly into the eye area before it sets
  • Breakouts in extremely acne-prone users if the rest of the formula is very rich

If you notice any of these effects stop using the product and seek advice from a healthcare professional.

Comedogenic Rating

Rating: 1 out of 5. Polyglyceryl-10 Dodecacaprylate is a large ester molecule that sits on the surface, spreads thinly and is easily removed with normal cleansing, so it has little tendency to block pores. Its light slip and low oiliness mean it is generally safe for those prone to acne or breakouts.

The only time it might contribute to congestion is if it is paired with heavy butters or high levels of waxes in the same formula, in which case the overall product richness, not the emulsifier itself, could be the issue.

Summary

Polyglyceryl-10 Dodecacaprylate is a plant-based emulsifier that keeps oil and water blended, improves texture and helps actives spread evenly. It does this by anchoring its water-loving glycerin backbone to its oil-friendly caprylic tails, forming a bridge between the two phases so the formula stays smooth and stable.

The ingredient has gained modest popularity in clean beauty, baby care and sensitive skin lines thanks to its renewable source, biodegradability and PEG-free label appeal, though it is still less common than older emulsifiers.

Current data shows it to be low risk for irritation, allergy or pore clogging, making it safe for routine use. As with any new skincare product, patch test first to be sure your skin agrees.

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